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Mototsugu Muramaki Selected Research

O-(Chloroacetylcarbamoyl)fumagillol (TNP 470)

3/2005Synergistic inhibition of tumor growth and metastasis by combined treatment with TNP-470 and docetaxel in a human prostate cancer PC-3 model.
10/2004Synergistic inhibition of tumor growth and metastasis by combined treatment with TNP-470 and gemcitabine in a human bladder cancer KoTCC-1 model.
11/2003Introduction of midkine gene into human bladder cancer cells enhances their malignant phenotype but increases their sensitivity to antiangiogenic therapy.

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Mototsugu Muramaki Research Topics

Disease

28Neoplasms (Cancer)
11/2020 - 11/2003
22Prostatic Neoplasms (Prostate Cancer)
05/2016 - 02/2005
14Urinary Bladder Neoplasms (Bladder Cancer)
08/2010 - 11/2003
8Neoplasm Metastasis (Metastasis)
11/2020 - 10/2004
8Lymphatic Metastasis
12/2011 - 10/2004
7Renal Cell Carcinoma (Grawitz Tumor)
11/2020 - 10/2005
7Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
12/2014 - 09/2003
5Margins of Excision
11/2013 - 01/2006
4Nonseminomatous germ cell tumor
10/2010 - 09/2004
4Disease Progression
01/2006 - 05/2005
2Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
05/2022 - 01/2013
2Carcinoma (Carcinomatosis)
10/2020 - 12/2011
2Choriocarcinoma
12/2014 - 10/2010
2Extranodal Extension
07/2013 - 06/2010
2Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2013 - 02/2010
2Hyperplasia
09/2008 - 08/2003
2Testicular Neoplasms (Testicular Cancer)
07/2006 - 10/2004
2Transitional Cell Carcinoma
01/2006 - 05/2005
1Adrenocortical Carcinoma
05/2022
1Rheumatoid Arthritis
05/2022
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
05/2022
1Ureteral Obstruction
09/2020
1Hypertension (High Blood Pressure)
01/2016
1Postoperative Hemorrhage
06/2015
1Infections
01/2014
1Surgical Blood Loss
11/2013
1Chronic Renal Insufficiency
01/2013
1Non-Muscle Invasive Bladder Neoplasms
03/2012
1Cerebral Hemorrhage
04/2011
1Brain Neoplasms (Brain Tumor)
04/2011
1Thyroiditis
09/2010
1Hypothyroidism
09/2010

Drug/Important Bio-Agent (IBA)

8Cisplatin (Platino)FDA LinkGeneric
12/2014 - 09/2003
8ClusterinIBA
02/2010 - 02/2005
4Prostate-Specific Antigen (Semenogelase)IBA
06/2010 - 01/2006
4AndrogensIBA
09/2008 - 02/2005
3Methotrexate (Mexate)FDA LinkGeneric
05/2022 - 04/2008
3Paclitaxel (Taxol)FDA LinkGeneric
12/2014 - 01/2007
3Antisense OligonucleotidesIBA
06/2011 - 09/2008
3Therapeutic UsesIBA
03/2006 - 09/2005
3Proteins (Proteins, Gene)FDA Link
10/2005 - 11/2003
3OligodeoxyribonucleotidesIBA
05/2005 - 02/2005
3O-(Chloroacetylcarbamoyl)fumagillol (TNP 470)IBA
03/2005 - 11/2003
2Angiogenesis InhibitorsIBA
11/2020 - 11/2003
2OligonucleotidesIBA
05/2016 - 01/2007
2C-Reactive ProteinIBA
01/2014 - 05/2009
2Docetaxel (Taxotere)FDA Link
12/2012 - 03/2005
2Cadherins (E-Cadherin)IBA
03/2012 - 12/2011
2Etoposide (VP 16)FDA LinkGeneric
10/2010 - 12/2007
2Biomarkers (Surrogate Marker)IBA
02/2010 - 01/2006
2GemcitabineFDA Link
02/2009 - 10/2004
2Bleomycin (Blenoxane)FDA LinkGeneric
04/2008 - 12/2007
2Tumor Biomarkers (Tumor Markers)IBA
12/2007 - 09/2005
2HSP27 Heat-Shock ProteinsIBA
01/2007 - 03/2006
2Insulin-Like PeptidesIBA
05/2005 - 02/2005
1NivolumabIBA
11/2020
1CreatinineIBA
01/2015
1IfosfamideFDA LinkGeneric
12/2014
1ElementsIBA
12/2014
1Sunitinib (Sutent)FDA Link
04/2011
1Dactinomycin (Actinomycin)FDA LinkGeneric
10/2010
1Sorafenib (BAY 43-9006)FDA Link
09/2010
1Thyroid HormonesIBA
09/2010
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
09/2010
1Thyroxine (Levothyroxine)FDA LinkGeneric
09/2010
1Triiodothyronine (Liothyronine)FDA LinkGeneric
09/2010
1Pemetrexed (MTA)FDA Link
06/2010
1Interferon-alpha (Interferon Alfa)IBA
05/2009
1Interleukin-2 (IL2)IBA
05/2009
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
03/2009
1Plasminogen Activator Inhibitor 2IBA
03/2009
1Plasminogen Activator Inhibitor 1IBA
03/2009
1Urokinase Plasminogen Activator ReceptorsIBA
03/2009
1Plasminogen Activators (Plasminogen Activator)IBA
03/2009
1OGX-011IBA
02/2009

Therapy/Procedure

19Therapeutics
11/2020 - 11/2003
16Prostatectomy (Retropubic Prostatectomy)
12/2014 - 09/2005
9Drug Therapy (Chemotherapy)
12/2012 - 07/2004
8Nephrectomy
06/2015 - 05/2009
5Cystectomy
08/2010 - 05/2005
4Adrenalectomy
05/2022 - 08/2003
4Operative Time
06/2016 - 11/2013
4Neoadjuvant Therapy
11/2013 - 11/2005
3Warm Ischemia
06/2016 - 01/2015
3Castration
05/2016 - 06/2011
3Combination Drug Therapy (Combination Chemotherapy)
04/2008 - 09/2003
2Stents
09/2020 - 01/2006
2Induction Chemotherapy
12/2014 - 09/2004
2Nephroureterectomy
12/2011 - 01/2008
2Radiotherapy
04/2011 - 05/2005
2Lymph Node Excision (Lymph Node Dissection)
02/2010 - 09/2004
2Immunotherapy
05/2009 - 01/2004
2Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
07/2006 - 07/2004
1Metastasectomy
11/2020
1Transurethral Resection of Bladder
10/2020
1Duration of Therapy
01/2016
1Solid-State Lasers
03/2013
1Morcellation
03/2013
1Aftercare (After-Treatment)
04/2011
1MEA regimen
10/2010