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Gerardo Morfini Selected Research

Microtubule-Associated Proteins (Microtubule-Associated Protein 2)

1/2019Tau and Axonal Transport Misregulation in Tauopathies.
1/2017Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.
4/2012Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.
11/2011Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.
2/2009The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.
1/2002Fast axonal transport misregulation and Alzheimer's disease.

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Gerardo Morfini Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
10/2023 - 01/2002
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021 - 01/2002
5Tauopathies
01/2017 - 02/2009
3Hereditary Spastic Paraplegia
08/2021 - 02/2008
2Cognitive Dysfunction
01/2016 - 11/2011
2Neoplasms (Cancer)
07/2013 - 09/2011
1Multiple Sclerosis
01/2023
1Virus Diseases (Viral Diseases)
01/2021
1Pathologic Processes
01/2019
1Polyneuropathies (Polyneuropathy)
01/2015
1Peripheral Nervous System Diseases (PNS Diseases)
07/2013
1Demyelinating Diseases (Demyelinating Disease)
06/2013
1Globoid Cell Leukodystrophy (Krabbe Disease)
06/2013
1Astrocytoma (Pilocytic Astrocytoma)
09/2011
1Glioblastoma (Glioblastoma Multiforme)
09/2011
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
11/2010
1Parkinson Disease (Parkinson's Disease)
02/2007
1X-Linked Bulbo-Spinal Atrophy
07/2006
1Frontotemporal Dementia (Semantic Dementia)
01/2002
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2002

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
10/2023 - 07/2006
6Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
01/2019 - 01/2002
4SpastinIBA
08/2021 - 02/2008
2Amyloid (Amyloid Fibrils)IBA
10/2023 - 11/2013
2EnzymesIBA
08/2021 - 09/2011
2Phosphotransferases (Kinase)IBA
01/2021 - 01/2017
2tau Proteins (tau Protein)IBA
11/2016 - 01/2016
2KinesinsIBA
01/2016 - 06/2013
2Peptides (Polypeptides)IBA
11/2013 - 11/2009
2polyglutamineIBA
07/2006 - 02/2005
1JNK Mitogen-Activated Protein KinasesIBA
01/2023
1Protein Isoforms (Isoforms)IBA
11/2016
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2016
1Glycoproteins (Glycoprotein)IBA
01/2015
1ixabepilone (BMS 247550)FDA Link
07/2013
1eribulinFDA Link
07/2013
1Paclitaxel (Taxol)FDA LinkGeneric
07/2013
1Vincristine (Oncovin)FDA LinkGeneric
07/2013
1GalactosylceramidaseIBA
06/2013
1Psychosine (Galactosylsphingosine)IBA
06/2013
1SphingolipidsIBA
06/2013
1Adenosine Triphosphatases (ATPase)IBA
09/2011
1CopperIBA
11/2010
1ZincIBA
11/2010
1Superoxide Dismutase-1IBA
11/2010
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
11/2009
1Amyloid beta-PeptidesIBA
11/2009
11-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA
02/2007
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
02/2007
1Androgen Receptors (Androgen Receptor)IBA
07/2006

Therapy/Procedure

1Drug Therapy (Chemotherapy)
07/2013