Monique C Minnema Selected Research

Multiple Myeloma

2/2024	Identifying clinical response to daratumumab therapy in relapsed/refractory multiple myeloma using a patient-derived in vitro model.
11/2023	Wnt inhibitors reduce the unfolded protein response and enhance bortezomib-induced cell death in multiple myeloma.
10/2023	Treatment of primary plasma cell leukaemia with carfilzomib and lenalidomide-based therapy (EMN12/HOVON-129): final analysis of a non-randomised, multicentre, phase 2 study.
5/2023	NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma.
12/2022	Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma.
11/2022	Iberdomide plus dexamethasone in heavily pretreated late-line relapsed or refractory multiple myeloma (CC-220-MM-001): a multicentre, multicohort, open-label, phase 1/2 trial.
10/2022	Carfilzomib, Pomalidomide, and Dexamethasone As Second-line Therapy for Lenalidomide-refractory Multiple Myeloma.
1/2022	Targeting B-cell maturation antigen increases sensitivity of multiple myeloma cells to MCL-1 inhibition.
12/2021	Efficacy and safety of daratumumab combined with all-trans retinoic acid in relapsed/refractory multiple myeloma.
11/2021	Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma.

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Monique C Minnema Research Topics

Disease

35	Multiple Myeloma 02/2024 - 02/2010
13	Lymphoma (Lymphomas) 12/2023 - 03/2016
11	Waldenstrom Macroglobulinemia (Macroglobulinemia) 02/2024 - 01/2016
10	B-Cell Lymphoma (Lymphoma, B Cell) 01/2024 - 11/2020
10	Neoplasms (Cancer) 01/2023 - 11/2008
8	Immunoglobulin Light-chain Amyloidosis 01/2023 - 12/2018
7	Amyloidosis 01/2024 - 05/2013
7	Infections 10/2023 - 11/2011
5	Paraproteinemias (Monoclonal Gammopathy) 09/2023 - 06/2020
4	Cytokine Release Syndrome 01/2024 - 01/2021
4	Neutropenia 11/2023 - 01/2019
4	Peripheral Nervous System Diseases (PNS Diseases) 07/2022 - 04/2017
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 01/2019
3	Diarrhea 11/2023 - 10/2020
3	Pneumonia (Pneumonitis) 11/2023 - 10/2020
3	Monoclonal Gammopathy of Undetermined Significance 01/2023 - 01/2022
3	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2021 - 10/2016
3	Leukemia 01/2021 - 11/2011
3	Hematologic Neoplasms (Hematological Malignancy) 01/2017 - 11/2008
2	Atrial Fibrillation 11/2023 - 10/2020
2	Spasm (Spasms) 11/2023 - 10/2020
2	Glomerulonephritis 09/2023 - 06/2020
2	Polyneuropathies (Polyneuropathy) 08/2023 - 01/2022
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2023 - 12/2022
2	Body Weight (Weight, Body) 12/2022 - 09/2015
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2022 - 01/2019
2	Disease Progression 12/2021 - 02/2020
2	Cardiomyopathies (Cardiomyopathy) 01/2021 - 10/2018
2	Thrombocytopenia (Thrombopenia) 10/2020 - 10/2018
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2020 - 01/2019
2	Fatigue 10/2018 - 01/2017
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 04/2017 - 12/2011
1	Amyloid Plaque 01/2024
1	AIDS-Related Complex (ARC) 01/2024
1	Multiple Sclerosis 01/2024
1	Burkitt Lymphoma (Burkitt's Lymphoma) 12/2023
1	Hypertension (High Blood Pressure) 11/2023
1	Cryofibrinogenemia 09/2023
1	Neurologic Manifestations (Neurological Manifestations) 08/2023
1	Aspergillosis 02/2023
1	Drug-Related Side Effects and Adverse Reactions 02/2023
1	Transthyretin-Related Hereditary Amyloidosis 01/2023
1	Melanoma (Melanoma, Malignant) 01/2023
1	Plasma Cell Leukemia 01/2023
1	Sepsis (Septicemia) 11/2022
1	Schnitzler Syndrome 01/2022
1	Cryoglobulinemia 01/2022

Drug/Important Bio-Agent (IBA)

13	daratumumabIBA 02/2024 - 09/2015
13	Dexamethasone (Maxidex)FDA LinkGeneric 11/2022 - 02/2010
10	Lenalidomide (CC 5013)FDA Link 11/2022 - 04/2010
9	Bortezomib (Velcade)FDA Link 11/2023 - 10/2013
9	Proteins (Proteins, Gene)FDA Link 09/2023 - 12/2014
8	Immunoglobulin M (IgM)IBA 08/2023 - 11/2016
7	Chimeric Antigen ReceptorsIBA 08/2023 - 11/2021
5	Biomarkers (Surrogate Marker)IBA 02/2024 - 07/2022
5	axicabtagene ciloleucelIBA 01/2024 - 01/2021
5	Rituximab (Mabthera)FDA Link 12/2023 - 01/2019
5	Monoclonal AntibodiesIBA 01/2023 - 01/2016
5	Proteasome InhibitorsIBA 11/2022 - 01/2017
5	Thalidomide (Thalomid)FDA Link 10/2020 - 02/2010
4	ibrutinibIBA 02/2024 - 01/2018
4	Amyloid (Amyloid Fibrils)IBA 01/2023 - 01/2021
4	Melphalan (Alkeran)FDA LinkGeneric 11/2019 - 02/2010
3	zanubrutinibIBA 02/2024 - 10/2020
3	Agammaglobulinaemia Tyrosine KinaseIBA 02/2024 - 02/2020
3	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2024 - 12/2018
3	tocilizumab (atlizumab)FDA Link 01/2024 - 01/2021
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2024 - 01/2021
3	ParaproteinsIBA 07/2022 - 01/2018
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2020
2	Carmustine (FIVB)FDA Link 01/2024 - 01/2019
2	Methotrexate (Mexate)FDA LinkGeneric 01/2024 - 01/2019
2	Teniposide (VM 26)FDA Link 01/2024 - 01/2019
2	brexucabtagene autoleucelIBA 01/2023 - 12/2022
2	pomalidomideIBA 11/2022 - 10/2022
2	Immunomodulating AgentsIBA 11/2022 - 10/2018
2	carfilzomibIBA 10/2022 - 08/2020
2	ixazomibIBA 01/2022 - 01/2017
2	B-Cell Maturation AntigenIBA 01/2022 - 01/2018
2	Immunoglobulins (Immunoglobulin)IBA 06/2020 - 10/2016
2	Minor Histocompatibility AntigensIBA 12/2014 - 11/2008
1	Immunoglobulin A (IgA)IBA 01/2024
1	Immunoglobulin lambda-ChainsIBA 01/2024
1	Prednisolone (Predate)FDA LinkGeneric 01/2024
1	CryoglobulinsIBA 09/2023
1	Blood Coagulation Factors (Coagulation Factor)IBA 09/2023
1	Voriconazole (Vfend)FDA LinkGeneric 02/2023
1	SerpinsIBA 01/2023
1	Bendamustine Hydrochloride FDA Link 01/2023
1	iberdomideIBA 11/2022
1	Myelin-Associated GlycoproteinIBA 07/2022

Therapy/Procedure

26	Therapeutics 02/2024 - 12/2014
10	Stem Cell Transplantation 07/2023 - 11/2008
7	Drug Therapy (Chemotherapy) 12/2023 - 11/2011
4	Immunotherapy 10/2023 - 11/2008
4	Aftercare (After-Treatment) 10/2023 - 10/2018
2	Radiotherapy 01/2024 - 12/2019
2	Transplantation 01/2023 - 10/2016
2	Cell Transplantation 01/2023 - 04/2017
2	Hematopoietic Stem Cell Transplantation 12/2021 - 10/2016