Thomas C Mettenleiter Selected Research

Hemagglutinins (Hemagglutinin)

10/2022	Exploring Prime-Boost Vaccination Regimens with Different H1N1 Swine Influenza A Virus Strains and Vaccine Platforms.
12/2021	The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo.
12/2020	Non-basic amino acids in the hemagglutinin proteolytic cleavage site of a European H9N2 avian influenza virus modulate virulence in turkeys.
12/2020	Protection of Chickens with Maternal Immunity Against Avian Influenza Virus (AIV) by Vaccination with a Novel Recombinant Newcastle Disease Virus Vector.
10/2020	Immunization with Plant-Derived Multimeric H5 Hemagglutinins Protect Chicken against Highly Pathogenic Avian Influenza Virus H5N1.
3/2020	Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)-Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV.
1/2019	Variable impact of the hemagglutinin polybasic cleavage site on virulence and pathogenesis of avian influenza H7N7 virus in chickens, turkeys and ducks.
1/2018	A Dual Motif in the Hemagglutinin of H5N1 Goose/Guangdong-Like Highly Pathogenic Avian Influenza Virus Strains Is Conserved from Their Early Evolution and Increases both Membrane Fusion pH and Virulence.
12/2016	Composition of the Hemagglutinin Polybasic Proteolytic Cleavage Motif Mediates Variable Virulence of H7N7 Avian Influenza Viruses.
1/2016	A Unique Multibasic Proteolytic Cleavage Site and Three Mutations in the HA2 Domain Confer High Virulence of H7N1 Avian Influenza Virus in Chickens.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Thomas C Mettenleiter Research Topics

Disease

58	Infections 09/2023 - 09/2002
38	Influenza in Birds (Avian Flu) 12/2021 - 12/2003
8	Virus Diseases (Viral Diseases) 01/2023 - 05/2008
6	Newcastle Disease 12/2020 - 05/2006
4	Pseudorabies 10/2022 - 10/2008
3	African Swine Fever 01/2022 - 01/2018
3	Coinfection 01/2017 - 01/2012
2	COVID-19 09/2023 - 01/2023
2	Human Influenza (Influenza) 04/2019 - 05/2008
2	Rabies (Hydrophobia) 01/2019 - 01/2015
2	Necrosis 11/2010 - 05/2003
1	Orthomyxoviridae Infections 10/2022
1	Disease Progression 01/2022
1	Pneumococcal Pneumonia 10/2021
1	Inflammation (Inflammations) 01/2021
1	Peste-des-Petits-Ruminants 04/2020
1	Meningoencephalitis 01/2020
1	Encephalitis (Encephalitis, Rasmussen) 01/2020
1	Rhinitis 01/2020
1	Herpesviridae Infections (Herpesvirus Infection) 01/2017
1	Communicable Diseases (Infectious Diseases) 10/2015
1	Reinfection 10/2014
1	Blister (Bulla) 12/2012
1	Scrapie 02/2011
1	Bovine Spongiform Encephalopathy (Mad Cow Disease) 02/2011
1	Lymphopenia (Lymphocytopenia) 11/2010
1	Pneumonia (Pneumonitis) 11/2010
1	Type 2 Diabetes Mellitus (MODY) 03/2006
1	Poultry Diseases (Poultry Disease) 03/2006
1	Infectious Bovine Rhinotracheitis 05/2003
1	Vulvovaginitis 05/2003

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2003
26	Hemagglutinins (Hemagglutinin)IBA 10/2022 - 03/2006
25	VaccinesIBA 10/2022 - 12/2003
9	Neuraminidase (Sialidase)IBA 01/2023 - 02/2007
8	AntibodiesIBA 01/2013 - 11/2003
4	RNA (Ribonucleic Acid)IBA 01/2023 - 08/2009
4	AntigensIBA 12/2020 - 04/2014
4	Glycoproteins (Glycoprotein)IBA 01/2019 - 04/2003
3	ProteomeIBA 01/2022 - 10/2008
3	Viral AntigensIBA 01/2021 - 01/2020
3	Marker VaccinesIBA 12/2012 - 05/2006
2	Drinking WaterIBA 12/2022 - 03/2008
2	CytokinesIBA 01/2022 - 10/2021
2	Viral RNAIBA 01/2022 - 08/2014
2	Antiviral Agents (Antivirals)IBA 11/2021 - 01/2017
2	Basic Amino Acids (Basic Amino Acid)IBA 12/2020 - 03/2020
2	Rabies Vaccines (Rabies Vaccine)FDA Link 01/2019 - 01/2015
2	DNA (Deoxyribonucleic Acid)IBA 11/2011 - 06/2009
2	dUTP pyrophosphataseIBA 06/2011 - 08/2009
2	Combined VaccinesIBA 06/2011 - 05/2006
2	Codon (Codons)IBA 02/2011 - 09/2006
2	PhosphoproteinsIBA 02/2011 - 06/2010
2	Amino Acids FDA Link 01/2011 - 10/2008
2	IsotopesIBA 06/2010 - 10/2008
2	NucleoproteinsIBA 09/2009 - 06/2009
2	avian influenza A virus hemagglutininIBA 01/2009 - 05/2006
2	Glucose (Dextrose)FDA LinkGeneric 03/2006 - 11/2002
1	AutoantibodiesIBA 09/2023
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2023
1	mRNA VaccinesIBA 01/2023
1	Archaeal ProteinsIBA 01/2023
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Interferon Type IIBA 11/2021
1	FlagellinIBA 10/2021
1	pseudorabies virus glycoprotein DIBA 01/2021
1	GlycosaminoglycansIBA 01/2021
1	Heparin (Liquaemin)FDA LinkGeneric 01/2021
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2021
1	phosphatidylcholine-ceramide phosphocholine transferaseIBA 01/2021
1	Nucleic AcidsIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	Neutralizing AntibodiesIBA 01/2019
1	asoxime chloride (H16)IBA 01/2019
1	AcidsIBA 01/2018
1	Phenobarbital (Luminal)FDA Link 10/2017
1	Amantadine (Aman)FDA LinkGeneric 01/2017
1	Serine (L-Serine)FDA Link 11/2014
1	Proline (L-Proline)FDA Link 11/2014
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 10/2014
1	Influenza Vaccines (Influenza Vaccine)FDA Link 04/2014
1	TrypsinIBA 01/2013
1	Pancreatic Elastase (Elastase)IBA 01/2013
1	hexamethylene bisacetamide (HMBA)IBA 01/2012
1	Beclin-1IBA 11/2011
1	PrionsIBA 02/2011
1	HN ProteinIBA 02/2011
1	Creatine Kinase (Creatine Phosphokinase)IBA 11/2010
1	Alanine Transaminase (SGPT)IBA 11/2010
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2010
1	heparin-sepharoseIBA 06/2010
1	Ribosomal Proteins (Ribosomal Protein)IBA 10/2008
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 10/2008
1	HSP27 Heat-Shock ProteinsIBA 10/2008
1	Histocompatibility Antigens Class IIBA 05/2008
1	Peptides (Polypeptides)IBA 05/2008
1	SynaptophysinIBA 07/2006
1	O,O-diisopropyl-S-benzylthiophosphate (IBP)IBA 05/2003

Therapy/Procedure

3	Therapeutics 01/2019 - 01/2018
1	Ganglionectomy 01/2022