Gunnar Mellgren Selected Research

Cytochrome P-450 CYP2C9

3/2024

Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort.

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Gunnar Mellgren Research Topics

Disease

32	Obesity 01/2024 - 06/2010
30	Breast Neoplasms (Breast Cancer) 03/2024 - 11/2005
20	Insulin Resistance 01/2024 - 06/2010
12	Neoplasms (Cancer) 01/2024 - 06/2012
11	Type 2 Diabetes Mellitus (MODY) 05/2023 - 01/2013
9	Overweight 01/2024 - 08/2014
7	Weight Loss (Weight Reduction) 04/2023 - 01/2013
6	Inflammation (Inflammations) 01/2022 - 06/2010
5	Cardiovascular Diseases (Cardiovascular Disease) 09/2021 - 02/2015
4	Body Weight (Weight, Body) 03/2024 - 12/2017
4	Morbid Obesity 01/2024 - 01/2018
4	Abdominal Obesity 01/2023 - 08/2011
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 08/2011
3	Hypertension (High Blood Pressure) 01/2024 - 01/2013
3	Coronary Disease (Coronary Heart Disease) 01/2023 - 06/2015
3	Myocardial Infarction 01/2023 - 02/2015
3	Addison Disease (Addison's Disease) 10/2015 - 01/2004
2	Fatty Liver 05/2023 - 01/2021
2	Weight Gain 10/2021 - 12/2017
2	Atherosclerosis 10/2021 - 02/2015
2	Cushing Syndrome 05/2021 - 06/2017
2	Glucose Intolerance 01/2019 - 01/2018
2	Coronary Artery Disease (Coronary Atherosclerosis) 09/2017 - 01/2017
2	Stable Angina 06/2015 - 02/2015
2	Primary Hyperparathyroidism 01/2013 - 01/2011
2	Hyperthyroidism 04/2002 - 01/2002
1	Left Ventricular Dysfunction 01/2024
1	Noninfiltrating Intraductal Carcinoma (DCIS) 12/2023
1	Heartburn (Pyrosis) 10/2023

Drug/Important Bio-Agent (IBA)

17	Tamoxifen FDA LinkGeneric 03/2024 - 11/2005
14	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 08/2011
12	Estrogens (Estrogen)FDA Link 01/2022 - 06/2010
11	Estrogen ReceptorsIBA 12/2023 - 04/2010
11	Messenger RNA (mRNA)IBA 05/2023 - 04/2010
11	LipidsIBA 01/2023 - 06/2010
10	Proteins (Proteins, Gene)FDA Link 01/2024 - 06/2012
9	Insulin (Novolin)FDA Link 01/2023 - 01/2013
6	Biomarkers (Surrogate Marker)IBA 01/2024 - 05/2016
5	Hormones (Hormone)IBA 03/2024 - 12/2013
5	4-hydroxy-N-desmethyltamoxifenIBA 03/2024 - 01/2015
5	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 03/2024 - 09/2013
5	Estradiol (Delestrogen)FDA LinkGeneric 01/2024 - 01/2013
4	SteroidsIBA 01/2024 - 08/2009
4	CarbohydratesIBA 09/2023 - 01/2017
4	Tryptophan (L-Tryptophan)FDA Link 01/2023 - 02/2015
4	C-PeptideIBA 01/2023 - 01/2013
4	Triglycerides (Triacylglycerol)IBA 01/2021 - 08/2011
4	Transcription Factors (Transcription Factor)IBA 11/2020 - 06/2010
4	Nuclear Receptor Coactivator 2IBA 01/2019 - 04/2010
4	EnzymesIBA 11/2017 - 01/2004
3	CytokinesIBA 01/2024 - 02/2015
3	AdipokinesIBA 01/2024 - 06/2010
3	exemestane (Aromasin)FDA Link 01/2024 - 01/2022
3	Valine (L-Valine)FDA Link 05/2023 - 05/2018
3	Amino Acids FDA Link 01/2023 - 01/2021
3	Aromatase InhibitorsIBA 01/2023 - 01/2017
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 05/2017
3	ApolipoproteinsIBA 01/2023 - 01/2017
3	HDL CholesterolIBA 12/2019 - 01/2016
3	KynurenineIBA 01/2018 - 02/2015
3	Steroid 21-Hydroxylase (21 Hydroxylase)IBA 10/2015 - 01/2004
3	AutoantibodiesIBA 10/2015 - 01/2004
3	Steroid Receptors (Steroid Receptor)IBA 01/2015 - 04/2010
2	CholesterolIBA 09/2023 - 06/2018
2	Phenobarbital (Luminal)FDA Link 07/2023 - 01/2019
2	Branched-Chain Amino AcidsIBA 05/2023 - 01/2020
2	CeramidesIBA 01/2023 - 05/2018
2	Lipoproteins (Lipoprotein)IBA 01/2023 - 01/2021
2	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2023 - 01/2021
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2023 - 01/2022
2	Blood Glucose (Blood Sugar)IBA 10/2021 - 01/2021
2	NeopterinIBA 09/2021 - 01/2018
2	Bile Acids and Salts (Bile Acids)IBA 06/2021 - 08/2011
2	Cortisone FDA Link 05/2021 - 12/2013
2	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2021 - 12/2013
2	Caseins (Casein)FDA Link 01/2021 - 04/2020
2	Dietary ProteinsIBA 01/2021 - 09/2015
2	Fish ProteinsIBA 01/2021 - 01/2018
2	TabletsIBA 04/2020 - 06/2018
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 06/2018 - 05/2017
2	Vitamin B 6IBA 01/2018 - 01/2017
2	LigandsIBA 01/2017 - 01/2013
2	Epidermal Growth Factor (EGF)IBA 01/2017 - 06/2012
2	Neuregulin-1 (Neuregulin 1)IBA 01/2017 - 01/2013
2	Growth Factor ReceptorsIBA 06/2012 - 04/2010
2	ElectrolytesIBA 04/2002 - 01/2002
1	Cytochrome P-450 CYP2C9IBA 03/2024
1	Cytochrome P-450 CYP2D6 InhibitorsIBA 03/2024
1	Metformin (Glucophage)FDA LinkGeneric 01/2024
1	C-Reactive ProteinIBA 01/2024
1	afimoxifene (hydroxytamoxifen)IBA 12/2023
1	Blood Proteins (Serum Proteins)IBA 12/2023
1	CI 22IBA 12/2023
1	AcidsIBA 10/2023

Therapy/Procedure

6	Bariatric Surgery 01/2024 - 01/2013
5	Therapeutics 08/2019 - 01/2013
4	Gastrectomy 10/2023 - 01/2013
2	Glycemic Control 01/2023 - 01/2021
2	Drug Therapy (Chemotherapy) 08/2019 - 10/2016
2	Operative Surgical Procedures 01/2013 - 01/2011