Bruno Melillo Selected Research

Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)

5/2024	Bicyclic Pyrrolidine Inhibitors of Toxoplasma gondii Phenylalanine t-RNA Synthetase with Antiparasitic Potency In Vitro and Brain Exposure.
2/2024	Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure.
12/2021	Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.

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Bruno Melillo Research Topics

Disease

6	Infections 05/2024 - 10/2016
3	Neoplasms (Cancer) 04/2024 - 11/2023
2	Toxoplasmosis 02/2024 - 01/2022
2	Malaria 02/2024 - 12/2021
2	AIDS-Related Complex (ARC) 01/2016 - 05/2013
1	Prostatic Neoplasms (Prostate Cancer) 03/2024
1	Cryptosporidiosis 02/2024
1	Parasitic Diseases (Parasitic Disease) 02/2024
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Communicable Diseases (Infectious Diseases) 01/2020
1	HIV Infections (HIV Infection) 01/2017

Drug/Important Bio-Agent (IBA)

4	AzetidinesIBA 05/2024 - 01/2020
3	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 05/2024 - 12/2021
3	Phenylalanine (L-Phenylalanine)FDA Link 05/2024 - 12/2021
2	AcrylamidesIBA 04/2024 - 12/2023
2	Proteins (Proteins, Gene)FDA Link 02/2024 - 11/2023
2	azetidineIBA 12/2023 - 01/2022
2	Glycoproteins (Glycoprotein)IBA 02/2017 - 10/2016
2	AnionsIBA 01/2016 - 05/2013
1	Cysteine (L-Cysteine)FDA Link 04/2024
1	ChromatinIBA 03/2024
1	A-Form DNA (A-DNA)IBA 03/2024
1	LigandsIBA 03/2024
1	Transfer RNA (tRNA)IBA 12/2023
1	HydrolasesIBA 01/2022
1	NAD (NADH)IBA 01/2022
1	Interleukin Receptors (Interleukin Receptor)IBA 01/2022
1	NAD+ Nucleosidase (NAD(P) Nucleosidase)IBA 01/2022
1	PF 68742IBA 11/2019
1	Antiviral Agents (Antivirals)IBA 01/2018
1	AntibodiesIBA 02/2017
1	EpitopesIBA 02/2017
1	VaccinesIBA 01/2017