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Mark J McKeage Selected Research

Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)

1/2020Screening for anaplastic lymphoma kinase (ALK) gene rearrangements in non-small-cell lung cancer in New Zealand.
12/2018Incomplete uptake of EGFR mutation testing and its impact on estimation of mutation prevalence in patients with non-squamous NSCLC: A population-based study in New Zealand.
11/2017Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test.
8/2011Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer.
5/2011Clinical trials of vascular disrupting agents in advanced non--small-cell lung cancer.
12/2010Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) - retrospective analysis of pooled data.
4/2010Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer.
8/2009Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer.

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Mark J McKeage Research Topics

Disease

22Neoplasms (Cancer)
08/2018 - 10/2004
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 08/2009
3Lung Neoplasms (Lung Cancer)
01/2020 - 05/2011
3Colorectal Neoplasms (Colorectal Cancer)
12/2017 - 10/2013
3Necrosis
05/2011 - 04/2007
3Prostatic Neoplasms (Prostate Cancer)
01/2008 - 08/2005
2Atrophy
12/2015 - 11/2009
2Neutropenia
10/2011 - 08/2011
2Melanoma (Melanoma, Malignant)
10/2011 - 04/2011
2Fatigue
10/2011 - 04/2011
2Ovarian Neoplasms (Ovarian Cancer)
02/2008 - 01/2007
1Heart Failure
01/2018
1Hypertension (High Blood Pressure)
01/2018
1Pulmonary Hypertension
01/2018
1Carcinoma (Carcinomatosis)
07/2014
1Breast Neoplasms (Breast Cancer)
01/2014
1Hypoxia (Hypoxemia)
10/2012
1Drug-Related Side Effects and Adverse Reactions
10/2012
1Glioblastoma (Glioblastoma Multiforme)
10/2011
1Fever (Fevers)
10/2011
1Sarcoma (Soft Tissue Sarcoma)
10/2011
1Infections
10/2011
1Thrombocytopenia (Thrombopenia)
10/2011
1Anus Neoplasms (Anal Cancer)
10/2011
1Pain (Aches)
08/2011
1Disease Progression
05/2011
1Renal Cell Carcinoma (Grawitz Tumor)
04/2011
1Hemoptysis
12/2010
1Hemorrhage
12/2010
1Peripheral Nervous System Diseases (PNS Diseases)
11/2009
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2007
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
08/2005
1Body Weight (Weight, Body)
01/2003

Drug/Important Bio-Agent (IBA)

9vadimezanIBA
08/2011 - 03/2006
7PlatinumIBA
12/2017 - 08/2005
6Carboplatin (JM8)FDA LinkGeneric
01/2018 - 01/2007
6Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2017 - 11/2009
4Paclitaxel (Taxol)FDA LinkGeneric
08/2011 - 08/2009
4Cisplatin (Platino)FDA LinkGeneric
08/2010 - 08/2005
3Hormones (Hormone)IBA
01/2014 - 01/2007
3FlavonoidsIBA
05/2011 - 04/2010
3CytokinesIBA
04/2011 - 04/2007
2ErbB Receptors (EGF Receptor)IBA
12/2018 - 11/2017
2Proteins (Proteins, Gene)FDA Link
12/2017 - 04/2011
2CopperIBA
12/2017 - 11/2014
2DNA (Deoxyribonucleic Acid)IBA
11/2017 - 07/2014
2CalciumIBA
01/2017 - 10/2013
2MagnesiumIBA
01/2017 - 10/2013
2Biomarkers (Surrogate Marker)IBA
12/2015 - 04/2011
2PoisonsIBA
07/2014 - 02/2008
2TubulinIBA
05/2011 - 04/2010
2flavone acetic acidIBA
10/2010 - 04/2010
1Anaplastic Lymphoma KinaseIBA
01/2020
1Tyrosine Kinase InhibitorsIBA
01/2020
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
08/2018
1demcizumabIBA
01/2018
1Brain Natriuretic Peptide (Natrecor)FDA Link
01/2018
1LigandsIBA
01/2018
1Pemetrexed (MTA)FDA Link
01/2018
1Copper Transport ProteinsIBA
12/2017
1ChloridesIBA
12/2017
1Copper Transporter 1IBA
12/2017
1Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric
01/2017
1Calcium Gluconate (CBG)IBA
01/2017
1Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2015
1Gefitinib (Iressa)FDA Link
12/2015
1ArsenicIBA
11/2014
1MetalsIBA
11/2014
1IronIBA
11/2014
1CarcinogensIBA
11/2014
1ZincIBA
11/2014
1GadoliniumIBA
11/2014
1IonsIBA
11/2014
1N- (2- (dimethylamino)ethyl)- 2,6- dimethyl- 1- oxo- 1,2- dihydroxybenzo(b)- 1,6- naphthyridine- 4- carboxamideIBA
07/2014
1Type II DNA Topoisomerases (Topoisomerase II)IBA
07/2014
1gluconic acid (gluconate)FDA LinkGeneric
10/2013
1fluoromisonidazoleIBA
10/2012
1Membrane Transport Proteins (Biological Pump)IBA
10/2012
1PR-104IBA
10/2011
1PR-104AIBA
10/2011
1combretastatinIBA
05/2011
1InterferonsIBA
04/2011
1Fibronectins (Fibronectin)IBA
04/2011
1Interleukin-12 (IL 12)IBA
04/2011
1Transaminases (Aminotransferases)IBA
04/2011
1Capecitabine (Xeloda)FDA Link
08/2010
1Antineoplastic Agents (Antineoplastics)IBA
04/2010
1Acetic Acid (Vinegar)FDA LinkGeneric
08/2009
1phosphine (phosphane)IBA
02/2008
1Docetaxel (Taxotere)FDA Link
01/2008
1Prostate-Specific Antigen (Semenogelase)IBA
01/2008
1taxaneIBA
01/2008
1Prednisone (Sone)FDA LinkGeneric
01/2007
1satraplatin (JM 216)IBA
01/2007
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2004

Therapy/Procedure

16Drug Therapy (Chemotherapy)
01/2018 - 01/2003
7Therapeutics
01/2020 - 01/2008
1Intravenous Infusions
10/2011
1Radiotherapy
10/2011