Louise D McCullough Selected Research

Sirtuin 1

1/2019	Inhibition of calcium/calmodulin-dependent protein kinase kinase (CaMKK) exacerbates impairment of endothelial cell and blood-brain barrier after stroke.
1/2019	Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke.

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Louise D McCullough Research Topics

Disease

114	Stroke (Strokes) 01/2024 - 07/2003
42	Ischemic Stroke 01/2024 - 01/2007
31	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2024 - 09/2003
21	Infarction (Infarctions) 10/2023 - 09/2007
17	Inflammation (Inflammations) 04/2024 - 12/2012
14	Brain Injuries (Brain Injury) 12/2023 - 06/2008
14	Brain Ischemia (Cerebral Ischemia) 01/2023 - 04/2005
14	Ischemia 03/2021 - 01/2004
8	Neuroinflammatory Diseases 12/2023 - 12/2017
7	Cerebral Hemorrhage 06/2019 - 11/2013
6	COVID-19 01/2023 - 10/2020
5	Hypertension (High Blood Pressure) 01/2022 - 11/2013
4	Dysbiosis 04/2024 - 12/2020
4	Hemorrhage 01/2023 - 12/2013
3	Hemorrhagic Stroke 02/2024 - 01/2018
3	Neoplasms (Cancer) 10/2023 - 07/2022
3	Fibrosis (Cirrhosis) 01/2023 - 01/2018
3	Obesity 01/2022 - 05/2014
3	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2022 - 12/2018
3	Infections 01/2021 - 07/2011
3	Cognitive Dysfunction 11/2020 - 11/2016
3	Alzheimer Disease (Alzheimer's Disease) 10/2020 - 12/2017
3	Hypoxia (Hypoxemia) 04/2019 - 01/2012
3	Hypothermia 08/2013 - 07/2011
2	Nervous System Diseases (Neurological Disorders) 11/2023 - 01/2021
2	Sepsis (Septicemia) 01/2023 - 01/2021
2	Embolic Stroke 01/2023 - 01/2019
2	Frailty 01/2022 - 12/2018
2	Glioma (Gliomas) 12/2020 - 01/2020
2	Pre-Eclampsia (Preeclampsia) 01/2020 - 05/2014
2	Thrombosis (Thrombus) 10/2018 - 09/2014
2	Hyponatremia 10/2015 - 05/2014

Drug/Important Bio-Agent (IBA)

17	Estrogens (Estrogen)FDA Link 01/2023 - 01/2004
16	CytokinesIBA 10/2023 - 06/2013
14	salicylhydroxamic acid (SHAM)IBA 01/2021 - 05/2004
12	Biomarkers (Surrogate Marker)IBA 07/2022 - 01/2016
10	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2020 - 11/2005
9	Hormones (Hormone)IBA 03/2021 - 06/2008
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2010
8	Estradiol (Delestrogen)FDA LinkGeneric 12/2023 - 01/2004
8	Neuroprotective AgentsIBA 01/2021 - 05/2004
7	MicroRNAs (MicroRNA)IBA 01/2023 - 07/2011
6	Messenger RNA (mRNA)IBA 01/2023 - 02/2005
6	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 03/2014
6	Gonadal HormonesIBA 01/2016 - 08/2005
5	Adenosine Monophosphate (AMP)IBA 12/2023 - 11/2007
5	Interleukin-6 (Interleukin 6)IBA 11/2020 - 09/2012
5	Phosphotransferases (Kinase)IBA 01/2019 - 09/2012
5	Protein Isoforms (Isoforms)IBA 09/2013 - 11/2007
4	Complement System Proteins (Complement)IBA 10/2023 - 02/2015
4	ChemokinesIBA 01/2023 - 09/2013
4	RNA (Ribonucleic Acid)IBA 12/2021 - 12/2019
4	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021 - 01/2010
4	SteroidsIBA 01/2021 - 01/2004
4	Protein Kinases (Protein Kinase)IBA 08/2013 - 11/2007
4	AMP-Activated Protein KinasesIBA 02/2012 - 05/2005
3	Volatile Fatty AcidsIBA 04/2024 - 01/2020
3	Amyloid (Amyloid Fibrils)IBA 01/2022 - 12/2018
3	rac1 GTP-Binding ProteinIBA 01/2021 - 10/2018
3	Aromatase (CYP19)IBA 01/2021 - 09/2003
3	Glial Fibrillary Acidic ProteinIBA 01/2021 - 10/2018
3	Testosterone (Sustanon)FDA Link 01/2021 - 02/2011
3	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 01/2018
3	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2019 - 09/2012
3	Calcium-Calmodulin-Dependent Protein Kinase KinaseIBA 04/2019 - 09/2013
3	CaspasesIBA 07/2011 - 05/2009
2	Factor VIIa (Activated Factor VII)IBA 02/2024 - 09/2023
2	AntigensIBA 12/2023 - 01/2022
2	MucinsIBA 12/2023 - 05/2020
2	Neurotransmitter Agents (Neurotransmitter)IBA 10/2023 - 01/2020
2	Histamine (Histamine Dihydrochloride)FDA Link 10/2023 - 05/2020
2	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 01/2023
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 12/2020
2	Warfarin (Coumadin)FDA LinkGeneric 01/2023 - 04/2009
2	Interferon Regulatory FactorsIBA 01/2023 - 01/2021
2	Interleukin-10 (Interleukin 10)IBA 11/2021 - 01/2015
2	Histones (Histone)IBA 03/2021 - 01/2021
2	Myelin Basic ProteinIBA 01/2021 - 11/2016
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2021 - 10/2018
2	Cytidine Triphosphate (CTP)IBA 01/2021 - 10/2020
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 10/2018
2	Temozolomide (Temodar)FDA LinkGeneric 12/2020 - 01/2020
2	Immunoglobulin G (IgG)IBA 01/2020 - 02/2014
2	Bromodeoxyuridine (BrdU)IBA 01/2020 - 05/2015
2	Glucose (Dextrose)FDA LinkGeneric 12/2019 - 05/2005
2	Oxygen (Dioxygen)IBA 12/2019 - 05/2005
2	Fibronectins (Fibronectin)IBA 10/2019 - 12/2018
2	triphenyltetrazoliumIBA 04/2019 - 04/2009
2	Sirtuin 1IBA 01/2019 - 01/2019
2	Adenosine Triphosphate (ATP)IBA 11/2017 - 05/2005
2	Oral ContraceptivesIBA 04/2015 - 05/2014

Therapy/Procedure

37	Therapeutics 01/2024 - 11/2005
4	Ovariectomy (Oophorectomy) 12/2023 - 04/2009
4	Thrombectomy 01/2023 - 10/2018
2	Fecal Microbiota Transplantation 04/2024 - 01/2020
2	Induced Hypothermia 08/2023 - 07/2011
2	Secondary Prevention 01/2023 - 07/2003
2	Length of Stay 01/2019 - 01/2018
2	Contraindications 04/2017 - 12/2013
2	Treatment Delay 11/2016 - 09/2012