Tetsuya Matoba Selected Research

Myocardial Ischemia (Ischemic Heart Diseases)

9/2022	Dietary 7-ketocholesterol exacerbates myocardial ischemia-reperfusion injury in mice through monocyte/macrophage-mediated inflammation.
1/2021	Nanoparticle-Mediated Simultaneous Targeting of Mitochondrial Injury and Inflammation Attenuates Myocardial Ischemia-Reperfusion Injury.
3/2019	Architecture of the Japan Ischemic Heart Disease Multimodal Prospective Data Acquisition for Precision Treatment (J-IMPACT) System.
1/2017	Anti-inflammatory Nanomedicine for Cardiovascular Disease.
11/2016	Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation.
5/2016	Quantification of coronary flow using dynamic angiography with 320-detector row CT and motion coherence image processing: Detection of ischemia for intermediate coronary stenosis.
2/2016	Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening.
1/2015	A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model.
2/2006	Extracorporeal cardiac shock wave therapy ameliorates myocardial ischemia in patients with severe coronary artery disease.
9/2004	Usefulness of fasudil, a Rho-kinase inhibitor, to treat intractable severe coronary spasm after coronary artery bypass surgery.

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Tetsuya Matoba Research Topics

Disease

22	Inflammation (Inflammations) 09/2022 - 03/2006
20	Coronary Artery Disease (Coronary Atherosclerosis) 04/2024 - 02/2006
18	Atrial Fibrillation 04/2024 - 08/2018
16	Myocardial Infarction 01/2023 - 01/2015
14	Hemorrhage 12/2023 - 08/2018
10	Myocardial Ischemia (Ischemic Heart Diseases) 09/2022 - 09/2004
9	Heart Failure 12/2023 - 10/2012
8	Cardiovascular Diseases (Cardiovascular Disease) 12/2023 - 07/2003
8	Reperfusion Injury 09/2022 - 01/2015
8	Rupture 03/2022 - 01/2012
7	Thrombosis (Thrombus) 04/2024 - 01/2011
7	Acute Coronary Syndrome 07/2023 - 04/2010
7	Ischemia 01/2021 - 06/2009
5	Coronary Disease (Coronary Heart Disease) 09/2023 - 01/2019
5	Infarction (Infarctions) 01/2019 - 01/2016
5	Atherosclerotic Plaque (Atheroma) 09/2017 - 01/2012
4	Diabetes Mellitus 07/2023 - 05/2005
4	Atherosclerosis 01/2022 - 03/2006
4	Ventricular Remodeling 08/2017 - 01/2016
4	Neointima 12/2011 - 04/2009
3	Unstable Angina 12/2023 - 11/2021
3	Dyslipidemias (Dyslipidemia) 06/2023 - 04/2010
3	Stroke (Strokes) 12/2022 - 01/2021
3	ST Elevation Myocardial Infarction 09/2022 - 03/2022
3	Pulmonary Arterial Hypertension 11/2018 - 05/2015
3	Pathologic Constriction (Stenosis) 08/2018 - 01/2011
2	Embolism (Embolus) 12/2022 - 11/2021
2	Heart Arrest (Cardiac Arrest) 08/2022 - 01/2021
2	Hypertension (High Blood Pressure) 01/2022 - 02/2011
2	Vascular System Injuries 01/2020 - 12/2011
2	Vascular Diseases (Vascular Disease) 07/2016 - 02/2002
2	Coronary Stenosis (Coronary Artery Stenosis) 05/2016 - 01/2009
2	Vascular Remodeling 02/2011 - 06/2008
2	Spasm (Spasms) 09/2004 - 02/2002
1	Thrombocytopenia (Thrombopenia) 10/2023
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 09/2023
1	Hyperglycemia 07/2023
1	Critical Illness (Critically Ill) 02/2023
1	Diabetic Retinopathy (Retinopathy, Diabetic) 12/2022
1	Overweight 12/2022
1	Macular Edema 12/2022

Drug/Important Bio-Agent (IBA)

16	RivaroxabanIBA 04/2024 - 08/2018
14	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2023 - 07/2003
12	pitavastatin (itavastatin)FDA Link 01/2022 - 08/2010
9	Therapeutic UsesIBA 01/2021 - 01/2012
7	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2023 - 08/2018
7	Angiotensin IIIBA 01/2022 - 09/2008
6	CholesterolIBA 12/2023 - 01/2012
5	Apolipoproteins E (ApoE)IBA 01/2022 - 01/2012
4	omega-Chloroacetophenone (Mace)IBA 12/2023 - 01/2022
4	Ezetimibe (Zetia)FDA Link 08/2023 - 01/2012
4	AnticoagulantsIBA 01/2023 - 08/2018
4	Pioglitazone (Actos)FDA Link 01/2019 - 10/2012
4	MonocrotalineIBA 11/2018 - 02/2011
3	Biomarkers (Surrogate Marker)IBA 12/2023 - 03/2016
3	OxysterolsIBA 06/2023 - 01/2012
3	CreatinineIBA 01/2023 - 01/2022
3	ApolipoproteinsIBA 01/2022 - 10/2013
3	Mitochondrial Permeability Transition PoreIBA 01/2021 - 02/2016
3	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2021 - 02/2016
3	SolutionsIBA 01/2019 - 11/2016
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 02/2014 - 12/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2009 - 03/2006
3	Cyclophilin AIBA 06/2009 - 03/2006
2	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2023 - 09/2023
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2022 - 04/2009
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2022 - 11/2021
2	Phosphotransferases (Kinase)IBA 09/2022 - 01/2011
2	Oxidoreductases (Dehydrogenase)IBA 09/2022 - 01/2017
2	glycolic acid (glycolate)IBA 01/2021 - 01/2016
2	LipidsIBA 01/2017 - 01/2012
2	Peptide Hydrolases (Proteases)FDA Link 07/2016 - 03/2016
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2016 - 10/2012
2	Matrix Metalloproteinases (MMPs)IBA 03/2016 - 01/2012
2	Imatinib Mesylate (Gleevec)FDA Link 05/2015 - 01/2011
2	Platelet-Derived Growth FactorIBA 05/2015 - 01/2011
2	Sirolimus (Rapamycin)FDA Link 01/2013 - 01/2009
2	Vasodilator Agents (Vasodilators)IBA 09/2004 - 07/2003
2	rho-Associated KinasesIBA 09/2004 - 02/2002
1	Streptokinase FDA Link 12/2023
1	LDL CholesterolIBA 09/2023
1	oxidized low density lipoproteinIBA 09/2023
1	lathosterolIBA 07/2023
1	campesterolIBA 07/2023
1	Nitroglycerin (Dynamite)FDA LinkGeneric 10/2022
1	RNA (Ribonucleic Acid)IBA 09/2022
1	Small Interfering RNA (siRNA)IBA 09/2022
1	Acetylcysteine (Siran)FDA LinkGeneric 09/2022
1	7-ketocholesterolIBA 09/2022
1	Oxygen (Dioxygen)IBA 08/2022

Therapy/Procedure

31	Therapeutics 04/2024 - 09/2004
12	Percutaneous Coronary Intervention 12/2023 - 02/2006
7	Stents 12/2023 - 01/2009
5	Intravenous Administration 01/2019 - 02/2014
4	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2019 - 09/2004
2	Ligation 01/2019 - 06/2008
2	Drug-Eluting Stents 01/2013 - 01/2011
2	Intramuscular Injections 10/2012 - 06/2009
1	Extracorporeal Membrane Oxygenation 02/2023
1	Resuscitation 01/2023