Ryo Matoba Selected Research

Lung Neoplasms (Lung Cancer)

1/2022	Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody.
3/2016	Identification of Individual Cancer-Specific Somatic Mutations for Neoantigen-Based Immunotherapy of Lung Cancer.
8/2015	High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients.

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Ryo Matoba Research Topics

Disease

12	Neoplasms (Cancer) 01/2023 - 09/2004
7	Epiretinal Membrane (Epiretinal Membranes) 01/2024 - 08/2021
4	Retinal Perforations 03/2024 - 12/2017
4	Retinal Detachment (Retinal Detachments) 10/2023 - 12/2020
4	Stomach Neoplasms (Stomach Cancer) 01/2023 - 07/2019
3	Hemorrhage 04/2024 - 04/2015
3	Polypoidal Choroidal Vasculopathy 04/2024 - 04/2015
3	Vision Disorders (Hemeralopia) 01/2024 - 01/2022
3	Lung Neoplasms (Lung Cancer) 01/2022 - 08/2015
3	Breast Neoplasms (Breast Cancer) 01/2012 - 01/2002
2	Macular Degeneration (Age-Related Maculopathy) 04/2024 - 04/2015
2	Blister (Bulla) 09/2023 - 10/2020
2	Colorectal Neoplasms (Colorectal Cancer) 06/2023 - 12/2009
2	Knee Osteoarthritis 12/2022 - 01/2019
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 03/2016
2	Proliferative Vitreoretinopathy 10/2020 - 01/2017
2	Rheumatoid Arthritis 01/2016 - 09/2009
1	Glaucoma 03/2024
1	Cataract (Cataracts) 03/2024
1	Ganglion Cysts (Ganglion) 03/2024
1	Polydactyly (Polydactylism) 12/2022
1	Adenocarcinoma 08/2022
1	Pleural Effusion (Pleural Effusions) 08/2022
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	Necrosis 09/2021
1	Retinal Diseases 08/2021
1	Metaplasia 08/2021
1	Psoas Abscess 04/2021
1	Abscess 04/2021
1	Knee Injuries (Knee Injury) 01/2019
1	Circulating Neoplastic Cells 01/2019
1	Osteoarthritis 01/2019
1	Scotoma (Scintillating Scotoma) 12/2017
1	Angioid Streaks 04/2015
1	Myopia 04/2015
1	Glioma (Gliomas) 03/2015
1	Carcinogenesis 03/2015
1	Glioblastoma (Glioblastoma Multiforme) 03/2015
1	Inflammation (Inflammations) 09/2009
1	AIDS-Related Complex (ARC) 09/2009
1	Hepatocellular Carcinoma (Hepatoma) 09/2004

Drug/Important Bio-Agent (IBA)

10	Retinaldehyde (Retinal)IBA 03/2024 - 04/2015
4	Tissue Plasminogen Activator (Alteplase)FDA Link 09/2021 - 03/2015
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 07/2019
3	NivolumabIBA 01/2023 - 07/2019
2	MicroRNAs (MicroRNA)IBA 03/2015 - 01/2012
2	Proteins (Proteins, Gene)FDA Link 01/2012 - 09/2009
1	afliberceptIBA 04/2024
1	A-factor (Streptomyces)IBA 07/2023
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2023
1	binimetinibIBA 06/2023
1	Irinotecan (Camptosar)FDA LinkGeneric 06/2023
1	encorafenibIBA 06/2023
1	Cetuximab (Erbitux)FDA Link 06/2023
1	LigandsIBA 01/2023
1	Nucleic AcidsIBA 08/2022
1	Stearoyl-CoA DesaturaseIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	CateninsIBA 01/2022
1	Therapeutic UsesIBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Nonesterified Fatty Acids (NEFA)IBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2022
1	Methicillin (Metin)FDA Link 04/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2021
1	Vancomycin FDA LinkGeneric 04/2021
1	FluorocarbonsIBA 10/2020
1	ParaffinIBA 11/2019
1	Formaldehyde (Formol)FDA Link 11/2019
1	Circulating Tumor DNAIBA 01/2019
1	nitinolIBA 12/2017
1	Retinal Pigments (Pigments, Visual)IBA 01/2017
1	VaccinesIBA 03/2016
1	Tumor Necrosis Factor InhibitorsIBA 01/2016
1	Abatacept (Orencia)FDA Link 01/2016
1	tocilizumab (atlizumab)FDA Link 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 08/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2012
1	Small Interfering RNA (siRNA)IBA 12/2009
1	Infliximab (Remicade)FDA Link 09/2009
1	C-Reactive ProteinIBA 09/2009
1	salicylhydroxamic acid (SHAM)IBA 09/2009
1	Docetaxel (Taxotere)FDA Link 01/2005
1	Interferon-alpha (Interferon Alfa)IBA 09/2004
1	Fluorouracil (Carac)FDA LinkGeneric 09/2004

Therapy/Procedure

10	Therapeutics 06/2023 - 01/2002
6	Vitrectomy 03/2024 - 04/2015
3	Traction 01/2024 - 09/2023
3	Transplantation 09/2023 - 01/2019
3	Immunotherapy 01/2022 - 03/2016
1	Surgical Instruments (Clip) 01/2024
1	Scleral Buckling 10/2023
1	Drug Therapy (Chemotherapy) 06/2023
1	Osteotomy 12/2022
1	Diathermy 10/2020
1	Gastrectomy 11/2019
1	Aftercare (After-Treatment) 07/2019
1	Lasers (Laser) 01/2019
1	Combination Drug Therapy (Combination Chemotherapy) 09/2004