Alexander Martens Selected Research

Biomarkers (Surrogate Marker)

1/2023	Early decrease of blood myeloid-derived suppressor cells during checkpoint inhibition is a favorable biomarker in metastatic melanoma.
1/2017	Establishing High Dimensional Immune Signatures from Peripheral Blood via Mass Cytometry in a Discovery Cohort of Stage IV Melanoma Patients.
12/2016	High GDF-15 Serum Levels Independently Correlate with Poorer Overall Survival of Patients with Tumor-Free Stage III and Unresectable Stage IV Melanoma.
11/2016	Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab.
10/2016	Increases in Absolute Lymphocytes and Circulating CD4+ and CD8+ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab.
1/2016	Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab.
1/2016	Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab.

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Alexander Martens Research Topics

Disease

15	Melanoma (Melanoma, Malignant) 01/2023 - 01/2014
5	Neoplasm Metastasis (Metastasis) 04/2017 - 03/2014
2	Infections 01/2022 - 01/2021
1	Central Nervous System Infections (Central Nervous System Infection) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Bacterial Meningitis 01/2021
1	Bacteremia 01/2020
1	Neoplasms (Cancer) 12/2016

Drug/Important Bio-Agent (IBA)

7	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2016
5	IpilimumabIBA 04/2017 - 01/2016
3	AntigensIBA 01/2015 - 01/2014
3	MART-1 AntigenIBA 01/2015 - 03/2014
2	Oxygen (Dioxygen)IBA 01/2022 - 01/2021
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2019 - 12/2016
2	Interleukin-2 (IL2)IBA 04/2017 - 07/2014
2	HLA-DR Antigens (HLA-DR)IBA 03/2014 - 01/2014
1	Immune Checkpoint InhibitorsIBA 01/2023
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Immunoglobulin M (IgM)IBA 01/2020
1	AntibodiesIBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 05/2019
1	Growth Differentiation Factor 15IBA 12/2016
1	pembrolizumabIBA 11/2016
1	Interleukin-4 (Interleukin 4)IBA 08/2014
1	Neoplasm Antigens (Tumor Antigens)IBA 03/2014

Therapy/Procedure

1	Therapeutics 05/2019
1	Injections 07/2014
1	Intralesional Injections 07/2014