Maurizio Margaglione Selected Research

Thrombosis (Thrombus)

3/2024	Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type.
6/2021	Severe systemic thrombosis in a young COVID-19 patient with a rare homozygous prothrombin G20210A mutation.
10/2020	Anemone study: prevalence of risk factors for superficial vein thrombosis in a large Italian population of blood donors.
8/2016	Pharmacogenetics of dabigatran etexilate interindividual variability.
4/2012	Hereditary protein C deficiency and thrombosis risk: genotype and phenotype relation in a large Italian family.
1/2012	Fatal pulmonary thromboembolism. A retrospective autopsy study: searching for genetic thrombophilias (Factor V Leiden (G1691A) and FII (G20210A) gene variants) and dating the thrombus.
6/2011	Increased warfarin consumption and residual fibrin turnover in thrombotic patients with primary antiphospholipid syndrome.
4/2008	Antithrombotic prophylaxis during pregnancy in women with deficiency of natural anticoagulants.
11/2007	Prognostic factors in noncirrhotic patients with splanchnic vein thromboses.
6/2006	Inherited abnormalities of fibrinogen: 10-year clinical experience of an Italian group.

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Maurizio Margaglione Research Topics

Disease

13	Thrombosis (Thrombus) 03/2024 - 01/2002
10	Hemorrhage 01/2023 - 06/2006
10	Thrombophilia 01/2021 - 08/2002
9	Venous Thromboembolism 10/2022 - 06/2003
7	Hemophilia A (Haemophilia) 01/2022 - 03/2007
6	Venous Thrombosis (Deep-Vein Thrombosis) 06/2024 - 04/2003
6	Hereditary Angioedemas 05/2021 - 03/2014
4	COVID-19 02/2022 - 06/2021
4	Myocardial Infarction 12/2004 - 06/2003
3	Activated Protein C Resistance (APC Resistance) 01/2018 - 03/2003
3	Pre-Eclampsia (Preeclampsia) 10/2009 - 01/2003
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 02/2024 - 03/2019
2	Neoplasms (Cancer) 06/2022 - 01/2013
2	Hypertension (High Blood Pressure) 09/2021 - 01/2003
2	Angioedema 05/2021 - 01/2020
2	Deafness (Deaf Mutism) 12/2020 - 10/2002
2	Stroke (Strokes) 01/2018 - 01/2003
2	Atrial Fibrillation 01/2018 - 08/2016
2	Protein S Deficiency (Deficiency, Protein S) 01/2018 - 04/2003
2	Phenylketonurias (Phenylketonuria) 02/2014 - 12/2013
2	Insulin Resistance 12/2012 - 02/2002
2	Atherosclerosis 06/2011 - 10/2009
2	Chronic Kidney Failure (Chronic Renal Failure) 12/2009 - 06/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2009 - 02/2005
2	Hyperhomocysteinemia 10/2009 - 07/2004
2	Fetal Growth Retardation (Intrauterine Growth Retardation) 10/2009 - 03/2009
2	Birth Weight (Birth Weights) 04/2006 - 02/2002
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 02/2024
1	Dmd-Associated Dilated Cardiomyopathy 02/2024
1	Muscular Diseases (Myopathy) 02/2024
1	Hemophilia B (Haemophilia B) 01/2023
1	Sepsis (Septicemia) 01/2023
1	Heart Failure 01/2022
1	Chronic Disease (Chronic Diseases) 01/2021
1	Asymptomatic Infections 12/2020
1	Thrombocytopenia (Thrombopenia) 12/2020
1	Menorrhagia 12/2020
1	Epistaxis (Nosebleed) 12/2020
1	Varicose Veins (Varicose Vein) 10/2020
1	Homocystinuria 08/2019
1	Methylmalonic acidemia 08/2019
1	Congenital Heart Defects (Congenital Heart Defect) 03/2019
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 03/2019
1	Syncope (Fainting) 03/2019
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 05/2018
1	Afibrinogenemia (Fibrinogen Deficiency) 05/2018

Drug/Important Bio-Agent (IBA)

10	Prothrombin (Factor II)IBA 03/2024 - 02/2002
9	factor V LeidenIBA 01/2021 - 01/2002
8	AnticoagulantsIBA 10/2021 - 11/2007
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2003
5	HomocysteineIBA 03/2024 - 01/2006
5	Factor V (Coagulation Factor V)IBA 01/2021 - 01/2002
5	Fibrinogen (Factor I)FDA Link 05/2018 - 12/2004
4	Factor VIII (Coagulation Factor VIII)IBA 01/2022 - 04/2008
4	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 10/2021 - 03/2012
4	Protein CIBA 01/2021 - 01/2002
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 08/2002
3	Protein SIBA 01/2021 - 04/2003
3	Immunoglobulin G (IgG)IBA 12/2020 - 04/2005
3	Angiopoietin-1IBA 01/2020 - 01/2018
3	Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA 12/2016 - 12/2013
3	DNA (Deoxyribonucleic Acid)IBA 03/2014 - 12/2002
3	Antiphospholipid AntibodiesIBA 06/2011 - 07/2004
2	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 03/2024 - 11/2003
2	Oral ContraceptivesIBA 01/2023 - 03/2008
2	ThrombomodulinIBA 10/2022 - 03/2004
2	von Willebrand FactorIBA 02/2022 - 01/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 11/2004
2	EnzymesIBA 09/2021 - 05/2021
2	BradykininIBA 05/2021 - 11/2019
2	AntithrombinsIBA 01/2021 - 04/2008
2	Factor XII (Hageman Factor)IBA 01/2020 - 01/2018
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 08/2019 - 01/2006
2	Vitamin K FDA Link 01/2018 - 09/2009
2	Dabigatran FDA Link 01/2018 - 08/2016
2	Factor VII (Proconvertin)IBA 01/2017 - 12/2002
2	InterferonsIBA 10/2014 - 01/2014
2	Ribavirin (Virazole)FDA LinkGeneric 10/2014 - 01/2014
2	plasma protein Z (protein Z)IBA 12/2011 - 04/2009
2	Annexin A5IBA 11/2010 - 03/2009
2	Amino Acids FDA Link 10/2009 - 10/2008
2	Plasminogen Activator Inhibitor 1IBA 06/2003 - 02/2002
1	Factor XI (Plasma Thromboplastin Antecedent)IBA 06/2024
1	DystrophinIBA 02/2024
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 01/2023
1	AlbuminsIBA 01/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2023
1	Fumigant 93 (D-D)IBA 06/2022
1	CytokinesIBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 09/2021
1	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 05/2021
1	CoagulantsIBA 01/2021
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 12/2020
1	Kininogens (Kininogen)IBA 01/2020
1	Adenosine Diphosphate (ADP)IBA 01/2020
1	PlasminogenIBA 01/2020

Therapy/Procedure

8	Therapeutics 01/2023 - 11/2007
1	Blood Transfusion (Blood Transfusions) 01/2021
1	Bed Rest (Bedrest) 10/2020
1	Surgical Casts (Plaster Cast) 10/2020