Brian C Mansfield Selected Research

Carrier Proteins (Binding Protein)

11/2017	Liver-directed gene therapy for murine glycogen storage disease type Ib.
10/2003	Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter.

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Brian C Mansfield Research Topics

Disease

20	Hepatorenal form of glycogen storage disease 01/2024 - 09/2002
17	Glycogen Storage Disease (Glycogenosis) 01/2023 - 03/2002
14	Glycogen Storage Disease IB 01/2023 - 03/2002
12	Neutropenia 11/2018 - 03/2002
10	Liver Cell Adenoma (Hepatocellular Adenoma) 01/2023 - 11/2009
7	Hypoglycemia (Reactive Hypoglycemia) 01/2021 - 03/2002
6	Carcinoma (Carcinomatosis) 01/2023 - 01/2017
6	Neoplasms (Cancer) 01/2020 - 10/2008
5	Hepatomegaly 05/2017 - 03/2002
4	Hyperuricemia 11/2013 - 03/2002
4	Hyperlipidemias (Hyperlipidemia) 11/2013 - 03/2002
3	Seizures (Absence Seizure) 11/2023 - 06/2015
3	Obesity 11/2017 - 09/2015
3	Insulin Resistance 11/2017 - 09/2015
3	Ovarian Neoplasms (Ovarian Cancer) 01/2011 - 10/2008
2	Retinal Degeneration 04/2024 - 11/2023
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 04/2024 - 11/2023
2	Disease Progression 04/2024 - 11/2023
2	Fibrosis (Cirrhosis) 01/2024 - 04/2010
2	Autosomal Recessive 3 Severe Congenital Neutropenia 05/2015 - 10/2010
2	Ovarian Epithelial Carcinoma 01/2011 - 10/2008
2	Communicable Diseases (Infectious Diseases) 01/2009 - 10/2008
2	Inflammation (Inflammations) 09/2006 - 10/2003
2	Diabetes Mellitus 03/2004 - 11/2003
1	Acute Kidney Injury (Acute Renal Failure) 01/2024
1	Chronic Renal Insufficiency 01/2024
1	Ciliopathies 01/2023
1	Retinal Diseases 01/2023
1	Immune System Diseases (Immune Disorders) 11/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2018
1	Carcinogenesis 01/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Blindness (Hysterical Blindness) 01/2016
1	Autosomal Recessive 4 Severe Congenital Neutropenia 05/2015
1	Hypoxia (Hypoxemia) 05/2014
1	Glycogen Storage Disease Type I 12/2010

Drug/Important Bio-Agent (IBA)

32	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 09/2002
16	Glucose-6-PhosphateIBA 01/2023 - 03/2002
7	EnzymesIBA 01/2024 - 09/2002
5	Blood Glucose (Blood Sugar)IBA 11/2023 - 11/2003
5	Sirtuin 1IBA 01/2023 - 01/2017
3	Retinaldehyde (Retinal)IBA 04/2024 - 01/2016
3	GlycogenIBA 01/2024 - 11/2009
3	Hypoglycemic Agents (Hypoglycemics)IBA 11/2023 - 06/2015
3	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 05/2015 - 03/2002
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 04/2011 - 03/2002
3	ChemokinesIBA 03/2008 - 10/2003
3	CalciumIBA 03/2007 - 10/2003
2	Rhodopsin (Visual Purple)IBA 04/2024 - 11/2023
2	CateninsIBA 01/2024 - 01/2017
2	OligonucleotidesIBA 11/2023 - 01/2023
2	Carrier Proteins (Binding Protein)IBA 11/2017 - 10/2003
2	Caspase 3 (Caspase-3)IBA 04/2011 - 06/2008
2	Biomarkers (Surrogate Marker)IBA 01/2011 - 10/2008
2	C-Reactive ProteinIBA 01/2009 - 10/2008
2	AntigensIBA 01/2009 - 10/2008
2	Proteins (Proteins, Gene)FDA Link 03/2004 - 10/2003
1	CollagenIBA 01/2024
1	ICG 001IBA 01/2024
1	Extracellular Matrix ProteinsIBA 01/2024
1	ReninIBA 01/2024
1	FlavonoidsIBA 01/2023
1	eupatilinIBA 01/2023
1	Antisense RNA (Anti-Sense RNA)IBA 01/2023
1	Codon (Codons)IBA 01/2020
1	SirtuinsIBA 05/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Pyruvate KinaseIBA 01/2018
1	HexokinaseIBA 01/2018
1	CarbohydratesIBA 11/2017
1	Cadherins (E-Cadherin)IBA 01/2017
1	fibroblast growth factor 21IBA 01/2017
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Peroxisome ProliferatorsIBA 05/2014
1	phosphatidylinositol 3,4,5-triphosphateIBA 04/2011
1	tempolIBA 04/2010
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 04/2010
1	AngiotensinsIBA 04/2010
1	AntioxidantsIBA 04/2010
1	NitrogenIBA 04/2010
1	Urea (Carbamide)FDA LinkGeneric 04/2010
1	Liver GlycogenIBA 11/2009
1	TenascinIBA 01/2009
1	Epidermal Growth Factor (EGF)IBA 01/2009
1	MyoglobinIBA 01/2009
1	Interleukin-18 (Interleukin 18)IBA 01/2009
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2009
1	Interleukin-6 (Interleukin 6)IBA 01/2009
1	Chemokine CCL3IBA 01/2009
1	Apolipoprotein C-IIIIBA 01/2009
1	ErbB Receptors (EGF Receptor)IBA 10/2008
1	Interleukin-8 (Interleukin 8)IBA 10/2008
1	Interleukin-10 (Interleukin 10)IBA 10/2008
1	Tissue Inhibitor of Metalloproteinase-1IBA 10/2008
1	Connective Tissue Growth FactorIBA 10/2008
1	HaptoglobinsIBA 10/2008
1	Phosphates (Orthophosphate)IBA 07/2008
1	AntiportersIBA 07/2008

Therapy/Procedure

4	Therapeutics 04/2011 - 03/2002