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Michael E Manning Selected Research

Angioedema

11/2023A phase 2 open-label extension study of prekallikrein inhibition with donidalorsen for hereditary angioedema.
1/2022Inhibition of Prekallikrein for Hereditary Angioedema.
10/2021Recognition and Management of Hereditary Angioedema: Best Practices for Dermatologists.
1/2020Long-Term Efficacy of Subcutaneous C1 Inhibitor in Pediatric Patients with Hereditary Angioedema.
9/2018Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema.
1/2014Escalating doses of C1 esterase inhibitor (CINRYZE) for prophylaxis in patients with hereditary angioedema.

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Michael E Manning Research Topics

Disease

9Hereditary Angioedemas
11/2023 - 05/2013
6Angioedema
11/2023 - 01/2014
1Inborn Genetic Diseases (Disease, Hereditary)
11/2020
1Hereditary Angioedema Types I and II
11/2018
1Injection Site Reaction
11/2018
1Dizziness (Lightheadedness)
11/2018
1Rare Diseases (Rare Disease)
01/2014

Drug/Important Bio-Agent (IBA)

4Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA
11/2020 - 05/2013
2PrekallikreinIBA
11/2023 - 01/2022
2donidalorsenIBA
11/2023 - 01/2022
2Monoclonal AntibodiesIBA
01/2023 - 11/2018
2human SERPING1 proteinIBA
01/2014 - 05/2013
1fibrin fragment D (D-dimer)IBA
11/2023
1Factor XIIa (Coagulation Factor XIIa)IBA
01/2023
1A-factor (Streptomyces)IBA
01/2023
1BradykininIBA
10/2021
1berotralstatIBA
01/2021
1Plasma KallikreinIBA
11/2018
1lanadelumabIBA
11/2018

Therapy/Procedure

5Therapeutics
01/2023 - 09/2018