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Guidalberto Manfioletti Selected Research

Breast Neoplasms (Breast Cancer)

12/2022HMGA1 Regulates the Expression of Replication-Dependent Histone Genes and Cell-Cycle in Breast Cancer Cells.
1/2022HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel.
10/2020Targeting the intrinsically disordered architectural High Mobility Group A (HMGA) oncoproteins in breast cancer: learning from the past to design future strategies.
6/2019The High Mobility Group A1 (HMGA1) Chromatin Architectural Factor Modulates Nuclear Stiffness in Breast Cancer Cells.
1/2019Editorial: Hormone Receptors and Breast Cancer.
4/2018High Mobility Group A (HMGA) proteins: Molecular instigators of breast cancer onset and progression.
1/2017HMGA1 regulates the Plasminogen activation system in the secretome of breast cancer cells.
1/2016Translating Proteomic Into Functional Data: An High Mobility Group A1 (HMGA1) Proteomic Signature Has Prognostic Value in Breast Cancer.
1/2016The Architectural Chromatin Factor High Mobility Group A1 Enhances DNA Ligase IV Activity Influencing DNA Repair.
8/2015A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness.
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Guidalberto Manfioletti Research Topics

Disease

32Neoplasms (Cancer)
09/2023 - 03/2002
12Breast Neoplasms (Breast Cancer)
12/2022 - 07/2006
3Neoplasm Metastasis (Metastasis)
01/2022 - 07/2006
3Triple Negative Breast Neoplasms
01/2022 - 08/2019
3Carcinoma (Carcinomatosis)
07/2006 - 03/2002
2Type 2 Diabetes Mellitus (MODY)
01/2012 - 07/2005
2Retinoblastoma (Glioblastoma, Retinal)
03/2009 - 05/2003
2Thyroid Neoplasms (Thyroid Cancer)
03/2006 - 03/2002
2Carcinogenesis
04/2003 - 07/2002
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2022
1Glioblastoma (Glioblastoma Multiforme)
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2013
1Ganglion Cysts (Ganglion)
12/2007
1Ganglioneuroma
12/2007
1Embryonal Rhabdomyosarcoma
12/2007
1Synovial Sarcoma (Synovioma)
11/2005
1Neurofibrosarcoma (MPNST)
11/2005
1Insulin Resistance
07/2005
1Prostatic Neoplasms (Prostate Cancer)
02/2005
1Benign Fibrous Histiocytoma (Dermatofibroma)
08/2004
1Dermatofibrosarcoma
08/2004
1Ovarian Epithelial Carcinoma
07/2003
1Ovarian Neoplasms (Ovarian Cancer)
07/2003
1Adenocarcinoma
07/2003
1Leiomyoma (Uterine Fibroids)
07/2002
1Tuberous Sclerosis (Bourneville's Disease)
07/2002
1Hamartoma
07/2002
1Lipoma (Lipomata)
07/2002
1Adenoma (Adenomas)
03/2002

Drug/Important Bio-Agent (IBA)

21Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2002
14HMGA ProteinsIBA
09/2023 - 07/2002
8ChromatinIBA
01/2022 - 09/2004
6Transcription Factors (Transcription Factor)IBA
01/2021 - 05/2003
4Histones (Histone)IBA
04/2023 - 06/2019
4DNA (Deoxyribonucleic Acid)IBA
01/2016 - 07/2002
4HMGA2 ProteinIBA
01/2013 - 07/2002
2Nuclear Proteins (Protein, Nuclear)IBA
12/2022 - 04/2003
2CyclinsIBA
01/2021 - 08/2015
2Insulin ReceptorIBA
01/2012 - 07/2005
1Antineoplastic Agents (Antineoplastics)IBA
09/2023
1Lactic Acid (Lactate)FDA LinkGeneric
04/2023
1EnzymesIBA
04/2023
1StathminIBA
01/2022
1Oncogene Proteins (Oncogene Protein)IBA
10/2020
1MicroRNAs (MicroRNA)IBA
01/2020
1CREB-Binding ProteinIBA
08/2019
1polypeptide 3 90kDa ribosomal protein S6 kinaseIBA
08/2019
1Hormones (Hormone)IBA
01/2019
1PlasminogenIBA
01/2017
1Plasminogen Activators (Plasminogen Activator)IBA
01/2017
1Biomarkers (Surrogate Marker)IBA
01/2013
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
07/2010
1ParaffinIBA
03/2009
1Genetic Markers (Genetic Marker)IBA
12/2007
1Transforming Growth Factor beta (TGF-beta)IBA
07/2006
1Small Interfering RNA (siRNA)IBA
03/2006
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2006
1Insulin (Novolin)FDA Link
07/2005
1PhosphoproteinsIBA
09/2004
1Factor XIIIaIBA
08/2004
1Staphylococcal Protein A (Protein A)IBA
05/2003
1High Mobility Group ProteinsIBA
04/2003
1HMGA1a ProteinIBA
04/2003
1Messenger RNA (mRNA)IBA
03/2002

Therapy/Procedure

2Therapeutics
08/2019 - 01/2019
2Drug Therapy (Chemotherapy)
12/2007 - 09/2004