Ichiro Manabe Selected Research

Therapeutics

7/2019	Cell Cycle Perturbation Induces Collagen Production in Fibroblasts.
1/2019	Editorial: New Trends in Vascular Inflammation Research: From Biology to Therapy.
10/2016	Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.
12/2014	Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.

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Ichiro Manabe Research Topics

Disease

15	Inflammation (Inflammations) 04/2020 - 02/2004
11	Fibrosis (Cirrhosis) 11/2022 - 01/2003
10	Atherosclerosis 11/2022 - 02/2004
9	Neoplasms (Cancer) 01/2018 - 08/2009
6	Insulin Resistance 09/2014 - 02/2004
6	Cardiovascular Diseases (Cardiovascular Disease) 11/2013 - 01/2005
6	Neointima 11/2013 - 01/2003
5	Obesity 12/2019 - 06/2007
4	Heart Failure 01/2020 - 01/2010
4	Hypoxia (Hypoxemia) 01/2019 - 07/2004
4	Hypertension (High Blood Pressure) 11/2016 - 06/2010
3	Vascular Diseases (Vascular Disease) 01/2012 - 05/2007
3	Hypertrophy 05/2011 - 01/2003
3	Vascular System Injuries 05/2007 - 01/2003
2	Atrophy 01/2022 - 01/2021
2	Hematologic Neoplasms (Hematological Malignancy) 12/2018 - 10/2017
2	Breast Neoplasms (Breast Cancer) 11/2017 - 03/2015
2	Lymphedema (Milroy Disease) 11/2017 - 03/2016
2	Choroidal Neovascularization 01/2016 - 10/2015
2	Carcinogenesis 12/2014 - 05/2014
2	Colorectal Neoplasms (Colorectal Cancer) 12/2014 - 05/2014
2	Neoplasm Metastasis (Metastasis) 12/2014 - 01/2014
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2014 - 08/2009
2	Thrombosis (Thrombus) 02/2012 - 01/2010
2	Coronary Artery Disease (Coronary Atherosclerosis) 02/2011 - 03/2007
2	Myocardial Infarction 02/2011 - 12/2009
2	Cardiomegaly (Heart Hypertrophy) 06/2010 - 01/2003
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2022
1	Meibomian Gland Dysfunction 01/2022
1	Muscular Atrophy (Muscle Atrophy) 01/2021
1	Sarcopenia 01/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 12/2019
1	Cardiomyopathies (Cardiomyopathy) 09/2019
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2018
1	Burns 01/2017
1	Vascular Remodeling 11/2016

Drug/Important Bio-Agent (IBA)

11	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2003
7	LipidsIBA 04/2020 - 05/2006
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2009
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2013 - 07/2004
4	CholesterolIBA 11/2022 - 05/2007
4	tamibaroteneIBA 01/2021 - 01/2003
4	Factor V (Coagulation Factor V)IBA 01/2021 - 01/2005
4	oxidized low density lipoproteinIBA 04/2020 - 05/2006
4	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2012
4	Angiotensin IIIBA 09/2015 - 01/2003
3	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2019 - 06/2010
3	Small Interfering RNA (siRNA)IBA 01/2018 - 11/2005
3	Angiopoietin-Like Protein 2IBA 03/2015 - 01/2014
3	IntegrinsIBA 01/2014 - 01/2010
3	AdipokinesIBA 01/2014 - 02/2004
3	Messenger RNA (mRNA)IBA 08/2009 - 01/2003
2	UbiquitinIBA 01/2022 - 01/2021
2	Ligases (Synthetase)IBA 01/2022 - 01/2021
2	ChromatinIBA 01/2021 - 06/2013
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 05/2006
2	RNA (Ribonucleic Acid)IBA 12/2019 - 01/2018
2	Acetylcysteine (Siran)FDA LinkGeneric 09/2019 - 02/2012
2	Co-Repressor ProteinsIBA 12/2018 - 10/2017
2	Antineoplastic Agents (Antineoplastics)IBA 05/2016 - 12/2014
2	Atorvastatin (Lipitor)FDA Link 03/2016 - 06/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2016 - 05/2006
2	CytokinesIBA 10/2015 - 08/2009
2	CateninsIBA 02/2015 - 05/2014
2	Matrix Metalloproteinases (MMPs)IBA 01/2014 - 11/2013
2	p38 Mitogen-Activated Protein KinasesIBA 01/2014 - 06/2010
2	Eicosapentaenoic AcidIBA 01/2014 - 12/2009
2	Nonesterified Fatty Acids (NEFA)IBA 01/2014 - 11/2013
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2014 - 12/2009
2	Interleukin-10 (Interleukin 10)IBA 11/2013 - 05/2006
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 11/2013 - 11/2010
2	Differentiation AntigensIBA 11/2013 - 11/2005
2	ApolipoproteinsIBA 06/2010 - 05/2006
2	AdiponectinIBA 03/2007 - 02/2004
2	RetinoidsIBA 05/2006 - 11/2005
1	FollistatinIBA 11/2022
1	NAD (NADH)IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	Coenzymes (Enzyme Cofactors)IBA 01/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2021
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2020
1	Long Noncoding RNAIBA 01/2020
1	CalciumIBA 01/2020
1	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 12/2019
1	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2019
1	Metformin (Glucophage)FDA LinkGeneric 09/2019
1	AntioxidantsIBA 09/2019
1	Oncostatin MIBA 01/2019
1	dihydropyrimidinaseIBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	Semaphorin-3AIBA 01/2018
1	Indocyanine Green (Cardio-Green)FDA LinkGeneric 11/2017
1	PeriostinIBA 11/2016
1	Desoxycorticosterone Acetate (DOCA)FDA Link 11/2016

Therapy/Procedure

4	Therapeutics 07/2019 - 12/2014
2	Lasers (Laser) 01/2016 - 01/2010
2	Stents 12/2012 - 11/2005
1	Conservative Treatment 11/2017