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Hiroshi Mabuchi Selected Research

pitavastatin (itavastatin)

7/2002Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, of patients with heterozygous familial hypercholesterolemia.
6/2002A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia.
1/2002Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison.

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Hiroshi Mabuchi Research Topics

Disease

31Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
12/2018 - 05/2002
22Atherosclerosis
09/2018 - 01/2002
21Hypercholesterolemia
07/2016 - 01/2002
20Coronary Artery Disease (Coronary Atherosclerosis)
01/2023 - 05/2002
17Coronary Disease (Coronary Heart Disease)
03/2017 - 01/2002
13Venous Thromboembolism
05/2024 - 01/2018
13Neoplasms (Cancer)
05/2024 - 11/2016
12Hemorrhage
05/2024 - 01/2018
12Hypertension (High Blood Pressure)
07/2018 - 01/2002
10Cardiovascular Diseases (Cardiovascular Disease)
03/2019 - 08/2003
8Xanthomatosis (Xanthoma)
09/2018 - 06/2005
7Aortic Valve Stenosis (Aortic Stenosis)
01/2023 - 12/2006
7Hyperlipidemias (Hyperlipidemia)
10/2017 - 01/2002
7Dyslipidemias (Dyslipidemia)
08/2016 - 08/2002
7Type 2 Diabetes Mellitus (MODY)
07/2011 - 08/2002
7Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2006 - 02/2002
6Hypertriglyceridemia
12/2023 - 01/2002
6Hyperlipoproteinemia Type III (Broad Beta Disease)
01/2015 - 10/2004
5Metabolic Syndrome (Dysmetabolic Syndrome X)
08/2016 - 01/2003
4Thromboembolism
04/2024 - 01/2019
4Body Weight (Weight, Body)
01/2022 - 02/2002
4Diabetes Mellitus
08/2020 - 01/2002
4Chronic Renal Insufficiency
04/2019 - 01/2016
4Cholesteryl Ester Transfer Protein Deficiency
11/2014 - 03/2004
4Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
02/2005 - 01/2002
3Sitosterolemia
12/2018 - 12/2017
3Stroke (Strokes)
07/2018 - 11/2005
3Fatty Liver
07/2015 - 01/2009
3Homozygous Familial Hypercholesterolemia
01/2015 - 02/2012
3Adenoma (Adenomas)
10/2010 - 04/2005
3Obesity
03/2010 - 01/2003
3Insulin Resistance
12/2007 - 08/2002
3Long QT Syndrome
07/2006 - 06/2003
3Sudden Death
01/2006 - 04/2005
3Heart Diseases (Heart Disease)
09/2005 - 04/2005
3Myocardial Infarction
09/2005 - 01/2002
3Nephrogenic Diabetes Insipidus
06/2004 - 01/2002
2Acute Coronary Syndrome
01/2023 - 01/2002
2Atrial Fibrillation
01/2023 - 01/2023
2Thrombophilia
01/2022 - 04/2019
2ST Elevation Myocardial Infarction
01/2022 - 07/2018
2Carotid Artery Diseases
12/2017 - 02/2007
2Abdominal Obesity
08/2016 - 08/2006
2Arthritis (Polyarthritis)
07/2016 - 09/2003
2Pancreatitis
07/2015 - 12/2005

Drug/Important Bio-Agent (IBA)

29LipidsIBA
12/2017 - 01/2002
25oxidized low density lipoproteinIBA
03/2019 - 12/2002
25CholesterolIBA
01/2016 - 01/2002
24LDL CholesterolIBA
12/2018 - 01/2002
18Triglycerides (Triacylglycerol)IBA
01/2018 - 01/2002
14LDL Lipoproteins (beta Lipoproteins)IBA
03/2019 - 12/2002
11Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2024 - 01/2002
11Lipoproteins (Lipoprotein)IBA
03/2019 - 10/2004
10HDL CholesterolIBA
07/2018 - 01/2003
10LDL Receptors (LDL Receptor)IBA
01/2016 - 12/2002
10Simvastatin (Zocor)FDA LinkGeneric
03/2010 - 05/2002
9Glucose (Dextrose)FDA LinkGeneric
08/2016 - 11/2004
7ApolipoproteinsIBA
12/2015 - 03/2004
6Proteins (Proteins, Gene)FDA Link
01/2015 - 01/2002
6Cholesterol Ester Transfer ProteinsIBA
11/2014 - 12/2002
5AnticoagulantsIBA
05/2024 - 11/2022
5Proprotein Convertase 9IBA
09/2018 - 07/2011
5Lipoprotein Lipase (Diacylglycerol Lipase)IBA
01/2018 - 12/2005
4vinyltriethoxysilane (VTES)IBA
04/2024 - 01/2019
4HDL LipoproteinsIBA
12/2023 - 01/2002
4Heparin (Liquaemin)FDA LinkGeneric
02/2022 - 03/2007
4colestimideIBA
09/2018 - 05/2005
4AldosteroneIBA
10/2010 - 02/2002
4Apolipoproteins E (ApoE)IBA
11/2009 - 03/2004
4Insulin (Novolin)FDA Link
05/2005 - 08/2002
3Ezetimibe (Zetia)FDA Link
09/2018 - 02/2012
3Adrenal Cortex Hormones (Corticosteroids)IBA
07/2015 - 09/2003
3Rosuvastatin Calcium (Crestor)FDA Link
02/2012 - 01/2002
3ReninIBA
04/2006 - 07/2003
3Sodium Channels (Sodium Channel)IBA
05/2005 - 06/2003
3Pravastatin (Pravachol)FDA LinkGeneric
03/2005 - 01/2002
3Oxidoreductases (Dehydrogenase)IBA
10/2004 - 01/2002
3Lysine (L-Lysine)FDA Link
07/2002 - 02/2002
3pitavastatin (itavastatin)FDA Link
07/2002 - 01/2002
3Troponin IIBA
07/2002 - 02/2002
2Brain Natriuretic Peptide (Natrecor)FDA Link
01/2019 - 07/2016
2SterolsIBA
12/2018 - 01/2010
2gamma-sitosterol (beta-sitosterol)IBA
09/2018 - 01/2015
2omega-Chloroacetophenone (Mace)IBA
07/2018 - 03/2015
2CalciumIBA
07/2018 - 02/2002
2Lipoprotein(a)IBA
07/2018 - 01/2016
2Apolipoproteins B (ApoB)IBA
05/2017 - 01/2009
2DNA (Deoxyribonucleic Acid)IBA
03/2017 - 12/2002
2Lipase (Acid Lipase)FDA Link
04/2016 - 11/2006
2IsotopesIBA
01/2015 - 02/2012

Therapy/Procedure

30Therapeutics
12/2022 - 05/2002
7Percutaneous Coronary Intervention
01/2023 - 07/2018
7Blood Component Removal (Apheresis)
09/2018 - 08/2003
5Secondary Prevention
05/2024 - 12/2002
3Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2022 - 09/2005
3Transcatheter Aortic Valve Replacement
01/2021 - 01/2019
3Drug Therapy (Chemotherapy)
10/2019 - 08/2003
2Stents
12/2023 - 01/2022
2Conservative Treatment
01/2023 - 01/2019
2Hormone Replacement Therapy (Therapy, Hormone Replacement)
07/2015 - 06/2005