Giuseppe Lungarella Selected Research

Interleukin-13

1/2015	Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysema.
12/2009	Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia.

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Giuseppe Lungarella Research Topics

Disease

15	Emphysema 01/2020 - 06/2002
13	Inflammation (Inflammations) 08/2022 - 05/2009
10	Fibrosis (Cirrhosis) 04/2021 - 04/2003
10	Chronic Obstructive Pulmonary Disease (COPD) 01/2020 - 06/2002
7	Pneumonia (Pneumonitis) 08/2022 - 10/2005
6	Lung Injury 01/2020 - 07/2008
4	Lung Diseases (Lung Disease) 05/2017 - 05/2009
3	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020 - 01/2017
2	Disease Progression 01/2020 - 10/2018
2	Pulmonary Emphysema 02/2013 - 08/2008
2	Metaplasia 12/2009 - 10/2005
1	Sarcopenia 04/2021
1	Chronic Renal Insufficiency 04/2021
1	Bronchiolitis 01/2020
1	Cytokine Release Syndrome 01/2020
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2020
1	Infections 01/2020
1	COVID-19 01/2020
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2017
1	Systemic Scleroderma (Systemic Sclerosis) 01/2016
1	Pulmonary Hypertension 08/2010
1	Silicosis 05/2009
1	Idiopathic Pulmonary Fibrosis 05/2009
1	Acute-Phase Reaction 03/2009
1	Hypoxia (Hypoxemia) 01/2008
1	Carcinogenesis 09/2006
1	Glycosuria 11/2005

Drug/Important Bio-Agent (IBA)

15	SmokeIBA 01/2020 - 07/2005
5	Purinergic Receptors (Receptors, Purine)IBA 05/2017 - 05/2010
5	Bleomycin (Blenoxane)FDA LinkGeneric 05/2017 - 12/2004
4	CytokinesIBA 01/2020 - 07/2005
4	Adenosine Triphosphate (ATP)IBA 01/2016 - 05/2010
3	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 07/2005
3	CollagenIBA 01/2016 - 05/2009
3	Transforming Growth Factor beta (TGF-beta)IBA 01/2015 - 07/2005
3	Phosphodiesterase 4 InhibitorsIBA 08/2010 - 10/2005
3	RoflumilastIBA 08/2010 - 10/2005
2	EnzymesIBA 01/2020 - 01/2015
2	Peptides (Polypeptides)IBA 10/2018 - 09/2012
2	Interleukin-13IBA 01/2015 - 12/2009
2	Pancreatic Elastase (Elastase)IBA 05/2010 - 07/2005
2	DesmosineIBA 10/2005 - 06/2002
1	Sirtuin 1IBA 08/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2022
1	AlarminsIBA 08/2022
1	Advanced Glycation End ProductsIBA 04/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2021
1	Phosphates (Orthophosphate)IBA 01/2020
1	ChemokinesIBA 01/2020
1	AnionsIBA 01/2020
1	Angiotensin-Converting Enzyme 2IBA 01/2020
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020
1	Interleukin-7 (Interleukin 7)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	sphingosine kinaseIBA 01/2020
1	Superoxides (Superoxide)IBA 01/2020
1	SphingosineIBA 01/2020
1	Interleukin-2 (IL2)IBA 01/2020
1	Cell Surface ReceptorsIBA 01/2020
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 10/2018
1	PAR-2 ReceptorIBA 11/2017
1	NucleotidesIBA 05/2017
1	Purinergic P2Y2 ReceptorsIBA 05/2017
1	purinoceptor P2Y6IBA 01/2017
1	AsbestosIBA 01/2016
1	Adenosine Triphosphatases (ATPase)IBA 01/2016
1	CD39 antigenIBA 01/2016
1	Dronabinol (THC)FDA LinkGeneric 01/2016
1	lenabasum (ajulemic acid)IBA 01/2016
1	ChitinasesIBA 01/2015
1	ArginaseIBA 01/2015
1	Oxidants (Oxidizing Agents)IBA 01/2015
1	8-hydroxyguanosineIBA 01/2015
1	Caspase 3 (Caspase-3)IBA 01/2015
1	DNA (Deoxyribonucleic Acid)IBA 01/2015
1	Formoterol Fumarate (Oxis)FDA Link 02/2013
1	AerosolsIBA 02/2013
1	Purinergic P2 Receptors (ADP Receptor)IBA 03/2011
1	Purinergic P2X7 ReceptorsIBA 03/2011
1	SteroidsIBA 08/2010
1	GoldIBA 08/2010
1	GasesIBA 08/2010
1	Proteinase-Activated ReceptorsIBA 12/2009
1	Silicon Dioxide (Silica)FDA LinkGeneric 05/2009
1	NF-KappaB Inhibitor alphaIBA 05/2009
1	NF-kappa B (NF-kB)IBA 05/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2009
1	Transcription Factors (Transcription Factor)IBA 05/2009
1	CeramidesIBA 07/2008
1	Superoxide DismutaseIBA 07/2008
1	CaspasesIBA 07/2008
1	SphingolipidsIBA 07/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2008
1	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 09/2006
1	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2005
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 10/2005
1	Transforming Growth Factor alpha (TGF-alpha)IBA 07/2005
1	Protease Inhibitors (Protease Inhibitor)IBA 07/2005

Therapy/Procedure

4	Therapeutics 01/2020 - 08/2010
1	Lung Transplantation 05/2009