Shuai Lu Selected Research

Alzheimer Disease (Alzheimer's Disease)

11/2020	Superparamagnetic iron oxide nanoparticles conjugated with Aβ oligomer-specific scFv antibody and class A scavenger receptor activator show therapeutic potentials for Alzheimer's Disease.
10/2020	A dual-ligand fusion peptide improves the brain-neuron targeting of nanocarriers in Alzheimer's disease mice.
7/2020	Yeast-Based Aβ1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice.
1/2020	Pharmacokinetics and absolute oral bioavailability of stemazole by UPLC-MS/MS and its bio-distribution through tritium labeling.
1/2020	Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with Aβ Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer's Disease.
11/2017	A mimotope of Aβ oligomers may also behave as a β-sheet inhibitor.
10/2017	PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice.
11/2016	A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses.
4/2016	A Novel Multifunctional Compound Camellikaempferoside B Decreases Aβ Production, Interferes with Aβ Aggregation, and Prohibits Aβ-Mediated Neurotoxicity and Neuroinflammation.
9/2014	Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease.

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Shuai Lu Research Topics

Disease

31	Neoplasms (Cancer) 05/2024 - 07/2012
10	Inflammation (Inflammations) 07/2024 - 07/2014
10	Alzheimer Disease (Alzheimer's Disease) 11/2020 - 09/2014
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2024 - 11/2016
6	Type 2 Diabetes Mellitus (MODY) 01/2023 - 02/2014
6	Insulin Resistance 01/2023 - 12/2015
6	Myocarditis (Carditis) 09/2022 - 01/2016
6	Non-alcoholic Fatty Liver Disease 04/2022 - 11/2016
4	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 01/2022
4	Breast Neoplasms (Breast Cancer) 02/2023 - 07/2018
4	Obesity 01/2023 - 11/2016
4	Body Weight (Weight, Body) 01/2023 - 07/2014
4	Infections 09/2022 - 07/2016
4	Roberts Syndrome 05/2014 - 01/2012
3	Glaucoma 12/2023 - 01/2020
3	Hypoxia (Hypoxemia) 11/2023 - 06/2013
3	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 01/2018
3	Male Infertility (Male Sterility) 06/2023 - 11/2021
3	Primary Hyperparathyroidism 01/2023 - 09/2020
3	Wounds and Injuries (Trauma) 06/2022 - 11/2010
3	Neoplasm Metastasis (Metastasis) 01/2021 - 07/2018
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 02/2014
3	Dementia (Dementias) 08/2019 - 04/2016
2	Carcinogenesis 07/2024 - 11/2023
2	COVID-19 01/2024 - 01/2023
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2023 - 01/2023
2	Muscular Atrophy (Muscle Atrophy) 01/2023 - 12/2021
2	Sepsis (Septicemia) 01/2023 - 12/2021
2	Pain (Aches) 11/2022 - 05/2016
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 06/2021 - 01/2021
2	Myocardial Infarction 06/2020 - 11/2017
2	Echinococcosis (Hydatid Cysts) 03/2020 - 01/2020
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 05/2016
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 02/2014
2	Parkinson Disease (Parkinson's Disease) 01/2019 - 11/2016
2	Pathologic Processes 01/2019 - 11/2016
2	Fibrosis (Cirrhosis) 11/2018 - 11/2017
2	Gliosis 01/2018 - 09/2014
2	Amyloid Plaque 10/2017 - 09/2014
2	Memory Disorders (Memory Loss) 10/2017 - 09/2014
2	Glucose Intolerance 09/2017 - 12/2015
2	Overweight 05/2017 - 11/2016
2	Neuroinflammatory Diseases 04/2016 - 09/2014
1	Hydrocephalus (Hydrocephaly) 07/2024
1	Brain Edema (Cerebral Edema) 07/2024
1	Hypogonadism (Hypergonadotropic Hypogonadism) 04/2024
1	Hyperthyroidism 01/2024

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2016
7	Biomarkers (Surrogate Marker)IBA 01/2024 - 11/2016
5	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 12/2015
5	Therapeutic UsesIBA 01/2022 - 01/2020
4	fms-Like Tyrosine Kinase 3IBA 02/2024 - 07/2018
4	Retinaldehyde (Retinal)IBA 01/2024 - 01/2020
4	LipidsIBA 02/2023 - 12/2015
4	Peptides (Polypeptides)IBA 10/2020 - 09/2014
4	VaccinesIBA 08/2020 - 05/2017
4	EpitopesIBA 07/2020 - 11/2016
4	Amyloid (Amyloid Fibrils)IBA 01/2019 - 09/2014
3	RNA (Ribonucleic Acid)IBA 01/2023 - 11/2017
3	LigandsIBA 10/2020 - 01/2018
3	AntigensIBA 08/2020 - 09/2015
3	CytokinesIBA 01/2020 - 09/2014
3	Phosphotransferases (Kinase)IBA 11/2019 - 10/2015
3	Insulin (Novolin)FDA Link 03/2019 - 11/2016
3	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 01/2017
2	NAD (NADH)IBA 10/2023 - 01/2023
2	Nicotinamide PhosphoribosyltransferaseIBA 10/2023 - 01/2023
2	Sirtuin 1IBA 03/2023 - 07/2022
2	AlbuminsIBA 07/2022 - 01/2022
2	Amino Acids FDA Link 04/2022 - 11/2017
2	theanineIBA 04/2022 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2022 - 11/2017
2	Long Noncoding RNAIBA 01/2022 - 01/2018
2	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 01/2020
2	Parathyroid Hormone (Parathormone)IBA 01/2021 - 09/2020
2	Scavenger Receptors (Scavenger Receptor)IBA 11/2020 - 01/2020
2	Amyloid beta-PeptidesIBA 07/2020 - 11/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2020
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 09/2014
2	CollagenIBA 11/2018 - 08/2012
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 11/2018 - 02/2014
2	Small Interfering RNA (siRNA)IBA 10/2018 - 11/2010
2	Triglycerides (Triacylglycerol)IBA 11/2016 - 11/2016
2	Ribosomal DNA (rDNA)IBA 05/2014 - 01/2012
2	CohesinsIBA 02/2014 - 01/2014
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 05/2024
1	Testosterone (Sustanon)FDA Link 04/2024
1	Proteolysis Targeting ChimeraIBA 02/2024
1	Methimazole (Thiamazole)FDA LinkGeneric 01/2024
1	Propranolol (Inderal)FDA LinkGeneric 01/2024
1	IronIBA 11/2023
1	methyl-4-nitrobenzenesulfonateIBA 11/2023
1	Liposomes (Liposome)IBA 11/2023

Therapy/Procedure

13	Therapeutics 05/2024 - 07/2012
3	Oral Administration 08/2023 - 01/2018
3	Immunotherapy 07/2020 - 05/2017
2	Transplantation 07/2024 - 06/2022
2	Drug Therapy (Chemotherapy) 01/2023 - 07/2018
2	Parathyroidectomy 10/2020 - 09/2020