Hong S Lu Selected Research

Losartan (Cozaar)

1/2023	LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling.
1/2023	Antisense oligonucleotides targeting hepatic angiotensinogen reduce atherosclerosis and liver steatosis in hypercholesterolemic mice.
10/2022	Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
12/2019	Angiotensinogen in hepatocytes contributes to Western diet-induced liver steatosis.

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Hong S Lu Research Topics

Disease

12	Atherosclerosis 01/2023 - 01/2019
11	Abdominal Aortic Aneurysm 01/2024 - 01/2019
7	Aortic Aneurysm (Aneurysm, Aortic) 01/2023 - 01/2019
6	Hypercholesterolemia 01/2023 - 01/2020
5	Hypertension (High Blood Pressure) 12/2023 - 01/2019
4	Aortic Rupture 10/2023 - 01/2021
3	Inflammation (Inflammations) 01/2024 - 01/2021
3	Aneurysm (Aneurysms) 01/2023 - 01/2020
3	Body Weight (Weight, Body) 12/2022 - 12/2019
3	Aortic Dissection 01/2022 - 01/2020
3	Thoracic Aortic Aneurysm 10/2021 - 10/2019
2	Fatty Liver 01/2023 - 12/2019
2	COVID-19 10/2020 - 06/2020
1	Metabolic Diseases (Metabolic Disease) 04/2024
1	Renovascular Hypertension (Goldblatt Syndrome) 12/2023
1	Vascular Remodeling 01/2023
1	Vascular System Injuries 01/2023
1	Neointima 01/2023
1	Infections 12/2022
1	Hypotension (Low Blood Pressure) 10/2022
1	Hemorrhage 01/2022
1	Hypovolemia 01/2022
1	Ascending Aorta Aneurysm 12/2021
1	Pulmonary Embolism 11/2021
1	Myocardial Infarction 11/2021
1	Hyperlipidemias (Hyperlipidemia) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Turner Syndrome (Turner's Syndrome) 01/2021
1	Hypertriglyceridemia 01/2021
1	Sepsis (Septicemia) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2020
1	Rupture 10/2020
1	Atherosclerotic Plaque (Atheroma) 10/2020
1	Thoracic Aorta Dissection 08/2020
1	Chronic Renal Insufficiency 10/2019
1	Neoplasms (Cancer) 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Carcinogenesis 01/2019

Drug/Important Bio-Agent (IBA)

11	AngiotensinogenIBA 04/2024 - 01/2019
11	Angiotensin IIIBA 12/2023 - 01/2019
8	ReninIBA 12/2023 - 01/2019
8	LDL Receptors (LDL Receptor)IBA 01/2023 - 01/2019
6	AngiotensinsIBA 01/2023 - 01/2019
4	AminopropionitrileIBA 10/2023 - 08/2020
4	Losartan (Cozaar)FDA LinkGeneric 01/2023 - 12/2019
3	Pancreatic Elastase (Elastase)IBA 01/2023 - 01/2021
3	LipidsIBA 12/2022 - 01/2021
2	Antisense OligonucleotidesIBA 01/2023 - 01/2023
2	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2019
2	Proprotein Convertase 9IBA 12/2022 - 01/2021
2	Serine Proteases (Serine Protease)IBA 12/2022 - 10/2020
2	RNA (Ribonucleic Acid)IBA 10/2022 - 12/2021
2	CholesterolIBA 01/2021 - 10/2020
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 01/2020
2	Apolipoproteins E (ApoE)IBA 01/2021 - 01/2019
2	Triglycerides (Triacylglycerol)IBA 01/2021 - 12/2019
2	Angiotensin-Converting Enzyme 2IBA 10/2020 - 06/2020
2	Amino Acids FDA Link 01/2020 - 01/2019
2	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2020 - 01/2019
1	ElastinIBA 01/2024
1	Peptides (Polypeptides)IBA 12/2023
1	Metformin (Glucophage)FDA LinkGeneric 01/2023
1	AcetylgalactosamineIBA 01/2023
1	PutrescineIBA 01/2023
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	Matrix Metalloproteinase 12IBA 01/2023
1	Irbesartan FDA LinkGeneric 10/2022
1	Type 1 Angiotensin ReceptorIBA 10/2022
1	FludrocortisoneIBA 01/2022
1	Annexin A1IBA 01/2022
1	Transforming Growth Factor-beta Type II ReceptorIBA 01/2022
1	Small Cytoplasmic RNAIBA 12/2021
1	Carrier Proteins (Binding Protein)IBA 11/2021
1	ElementsIBA 11/2021
1	Transcription Factors (Transcription Factor)IBA 11/2021
1	Succinic Acid (Succinate)IBA 11/2021
1	Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)IBA 11/2021
1	Adenosine Monophosphate (AMP)IBA 11/2021
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	Angiotensin Receptor AntagonistsIBA 10/2021
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 10/2021
1	Fibrillin-1IBA 10/2021
1	LigandsIBA 10/2021
1	Prorenin ReceptorIBA 01/2021
1	ApolipoproteinsIBA 01/2021
1	Histone DemethylasesIBA 01/2021
1	N-acetylVal-Nle(7,8)- allatotropin (5-13) (ATAA)IBA 10/2020
1	LDL CholesterolIBA 01/2020
1	SaltsIBA 01/2020
1	Angiotensin IIBA 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	oxidized low density lipoproteinIBA 01/2020
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2020
1	Sterol Regulatory Element Binding Protein 1IBA 12/2019
1	Proteoglycans (Proteoglycan)IBA 10/2019
1	Lipoproteins (Lipoprotein)IBA 10/2019
1	dipeptidaseIBA 01/2019

Therapy/Procedure

4	Therapeutics 01/2023 - 01/2019
1	Intraperitoneal Injections 01/2021