Hilary J Longhurst Selected Research

Angioedema

2/2024	CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema.
1/2022	Treatment of hereditary angioedema-single or multiple pathways to the rescue.
1/2021	Managing Chronic Urticaria and Recurrent Angioedema Differently with Advancing Age.
1/2018	Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.
1/2017	An open-label study to evaluate the long-term safety and efficacy of lanadelumab for prevention of attacks in hereditary angioedema: design of the HELP study extension.
6/2016	The Icatibant Outcome Survey: treatment of laryngeal angioedema attacks.
9/2014	Treatment of hereditary angioedema with icatibant: efficacy in clinical trials versus effectiveness in the real-world setting.
4/2012	Many faces of angioedema: focus on the diagnosis and management of abdominal manifestations of hereditary angioedema.
9/2010	Management of acute attacks of hereditary angioedema: potential role of icatibant.
9/2004	Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hilary J Longhurst Research Topics

Disease

29	Hereditary Angioedemas 02/2024 - 04/2007
10	Angioedema 02/2024 - 09/2004
4	Infections 12/2014 - 01/2004
2	Rare Diseases (Rare Disease) 01/2022 - 02/2019
2	Hereditary Angioedema Types I and II 01/2019 - 11/2018
2	Lymphopenia (Lymphocytopenia) 05/2018 - 01/2017
1	Anaphylaxis (Anaphylactic Shock) 01/2022
1	Urticaria (Hives) 01/2021
1	Dizziness (Lightheadedness) 11/2018
1	Injection Site Reaction 11/2018
1	Multiple Sclerosis 05/2018
1	Body Weight (Weight, Body) 01/2018
1	Overweight 01/2018
1	IgG Deficiency 01/2017
1	Chronic Disease (Chronic Diseases) 06/2016
1	Fever (Fevers) 06/2016
1	Inflammation (Inflammations) 06/2016
1	Pain (Aches) 06/2016
1	Hematologic Neoplasms (Hematological Malignancy) 05/2014
1	Enteritis 01/2014
1	Primary Immunodeficiency Diseases 01/2014
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2014
1	Abdominal Pain (Pain, Abdominal) 04/2012
1	Polymyositis 01/2011
1	Dermatomyositis (Dermatopolymyositis) 01/2011
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2011
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2007
1	Soft Tissue Infections 09/2004
1	Wiskott-Aldrich Syndrome 02/2002

Drug/Important Bio-Agent (IBA)

12	icatibantIBA 01/2022 - 09/2010
7	BradykininIBA 01/2022 - 09/2010
5	Kallikreins (Kallikrein)IBA 02/2024 - 01/2017
5	Plasma KallikreinIBA 11/2023 - 01/2017
5	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2022 - 01/2014
5	lanadelumabIBA 01/2021 - 01/2017
3	Bradykinin B2 ReceptorIBA 01/2022 - 09/2015
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 04/2012
2	Monoclonal AntibodiesIBA 11/2018 - 01/2017
2	Immunoglobulin M (IgM)IBA 01/2017 - 01/2014
2	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2014 - 01/2014
2	Immunoglobulins (Immunoglobulin)IBA 05/2014 - 01/2014
1	CRISPR-Associated Protein 9IBA 02/2024
1	sebetralstatIBA 11/2023
1	Antisense OligonucleotidesIBA 01/2022
1	ecallantide FDA Link 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021
1	Omalizumab (Xolair)FDA Link 01/2021
1	Non-Sedating Histamine H1 Antagonists (Histamine H1 Antagonists, Non Sedating)IBA 01/2021
1	KininsIBA 02/2019
1	Cladribine FDA LinkGeneric 05/2018
1	Alemtuzumab (Campath)FDA Link 05/2018
1	acivicin (AT 125)IBA 01/2018
1	berotralstatIBA 01/2018
1	EicosanoidsIBA 06/2016
1	LipidsIBA 06/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2014
1	AntibodiesIBA 05/2014
1	Anticonvulsants (Antiepileptic Drugs)IBA 05/2014
1	Rituximab (Mabthera)FDA Link 01/2014
1	conestat alfaIBA 01/2014
1	Phospholipases (Phospholipase)IBA 01/2014
1	Immunoglobulin A (IgA)IBA 01/2014
1	Immunoglobulin G (IgG)IBA 01/2014
1	Estrogens (Estrogen)FDA Link 04/2012
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2011
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2011
1	Complement C4 (Complement Component 4)IBA 04/2007
1	Hormones (Hormone)IBA 09/2004
1	Interferon-gamma (Interferon, gamma)IBA 01/2004
1	AutoantibodiesIBA 01/2004

Therapy/Procedure

11	Therapeutics 02/2024 - 09/2004
2	Drug Therapy (Chemotherapy) 01/2014 - 01/2004
1	Self Administration (Administration, Self) 07/2019
1	Injections 05/2018
1	Oral Administration 01/2018
1	Immunomodulation 01/2011
1	Debridement 09/2004
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/2002