Alberto Lleó Selected Research

Tauopathies

8/2017	Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.
1/2017	YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer's disease and other tauopathies.
12/2010	Tau phosphorylation and aggregation as a therapeutic target in tauopathies.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Alberto Lleó Research Topics

Disease

139	Alzheimer Disease (Alzheimer's Disease) 05/2024 - 02/2002
48	Dementia (Dementias) 05/2024 - 01/2008
34	Cognitive Dysfunction 01/2024 - 01/2008
24	Frontotemporal Dementia (Semantic Dementia) 03/2024 - 07/2005
21	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 12/2010
14	Down Syndrome (Down's Syndrome) 05/2024 - 01/2017
11	Parkinson Disease (Parkinson's Disease) 01/2020 - 01/2011
10	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2022 - 09/2014
8	Inflammation (Inflammations) 10/2023 - 01/2014
7	Disease Progression 11/2023 - 03/2012
7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 02/2016
7	Neuroinflammatory Diseases 01/2023 - 08/2015
5	Amyloidosis 12/2023 - 01/2016
5	Atrophy 11/2023 - 08/2014
5	Amyloid Plaque 01/2021 - 01/2008
4	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 11/2021 - 01/2016
4	Synucleinopathies 12/2017 - 01/2011
3	Primary Progressive Aphasia 01/2023 - 07/2017
3	Genetic Risk Score 01/2023 - 11/2020
3	Nervous System Diseases (Neurological Disorders) 01/2021 - 01/2017
3	Parkinsonian Disorders (Parkinsonism) 03/2018 - 01/2015
3	Tauopathies 08/2017 - 12/2010
3	Headache (Headaches) 01/2017 - 01/2014
2	Cerebral Cortical Thinning 04/2023 - 09/2015
2	Mental Disorders (Mental Disorder) 12/2022 - 04/2019
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 05/2020 - 07/2017
2	Multiple Sclerosis 10/2019 - 01/2017
2	Prodromal Symptoms 01/2019 - 01/2016
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2019 - 01/2008
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2014 - 02/2013
1	Chronic Renal Insufficiency 12/2023
1	Gliosis 04/2023
1	Major Depressive Disorder (Major Depressive Disorders) 12/2022
1	Vascular Remodeling 11/2022
1	Infections 01/2022
1	Guillain-Barre Syndrome 11/2020
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2020
1	Obesity 01/2020

Drug/Important Bio-Agent (IBA)

113	Biomarkers (Surrogate Marker)IBA 05/2024 - 05/2013
66	Amyloid (Amyloid Fibrils)IBA 05/2024 - 02/2002
45	Proteins (Proteins, Gene)FDA Link 05/2024 - 02/2002
16	Apolipoproteins E (ApoE)IBA 10/2023 - 01/2010
10	Amyloid beta-PeptidesIBA 07/2023 - 01/2008
9	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 08/2015 - 01/2008
7	Peptides (Polypeptides)IBA 01/2023 - 01/2011
7	ApolipoproteinsIBA 11/2022 - 01/2010
6	PresenilinsIBA 01/2014 - 02/2002
5	SynucleinsIBA 12/2017 - 01/2011
4	ProgranulinsIBA 03/2024 - 08/2012
4	Glial Fibrillary Acidic ProteinIBA 05/2023 - 12/2021
4	MicroRNAs (MicroRNA)IBA 01/2020 - 01/2017
4	Presenilin-1IBA 09/2016 - 05/2002
4	EnzymesIBA 01/2016 - 01/2012
4	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 03/2013 - 01/2010
3	Apolipoprotein E4IBA 05/2024 - 09/2015
3	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 01/2018
3	tau Proteins (tau Protein)IBA 05/2020 - 01/2018
3	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2019 - 08/2017
2	Vesicle-Associated Membrane Protein 2 (VAMP2)IBA 10/2023 - 01/2021
2	ProteomeIBA 01/2023 - 11/2022
2	ethyl 4-azidophenyl-1,4-dithiobutyrimidateIBA 11/2022 - 01/2020
2	Phosphotransferases (Kinase)IBA 01/2022 - 01/2017
2	Nerve Growth Factors (Neurotrophins)IBA 11/2021 - 01/2021
2	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 11/2021 - 01/2021
2	Threonine (L-Threonine)FDA Link 01/2021 - 01/2020
2	Complement System Proteins (Complement)IBA 01/2020 - 01/2019
2	ChemokinesIBA 01/2020 - 01/2018
2	Mitochondrial DNA (mtDNA)IBA 10/2019 - 01/2017
2	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2018 - 01/2016
2	sortilinIBA 01/2018 - 01/2016
2	ImmunosorbentsIBA 01/2016 - 09/2015
2	alpha-SynucleinIBA 09/2015 - 01/2009
2	Codon (Codons)IBA 01/2014 - 01/2011
2	CalciumIBA 01/2013 - 09/2012
2	Presenilin-2IBA 03/2004 - 08/2003
1	Cholinergic Agents (Cholinergics)IBA 11/2023
1	thimet oligopeptidase (endo-oligopeptidase)IBA 07/2023
1	Glutamate Receptors (Glutamate Receptor)IBA 12/2022
1	AMPA Receptors (AMPA Receptor)IBA 12/2022
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2022
1	verubecestatIBA 01/2022
1	antineoplaston A10 (A 10)IBA 01/2022
1	Chitinase-3-Like Protein 1IBA 10/2021
1	NeurograninIBA 10/2021
1	neuronal pentraxinIBA 01/2021
1	sharpinIBA 01/2021
1	Nerve Growth Factor (NGF)IBA 01/2021
1	N-acetylaspartate (N-acetyl aspartate)IBA 01/2021
1	Inositol (Myoinositol)IBA 01/2021
1	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2020
1	Reelin ProteinIBA 01/2020
1	Blood Proteins (Serum Proteins)IBA 11/2019

Therapy/Procedure

8	Therapeutics 11/2022 - 12/2010
1	Transcranial Direct Current Stimulation 01/2023
1	Speech Therapy (Therapy, Speech) 01/2023
1	Ligation 11/2022
1	Precision Medicine 01/2021