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Mingyao Liu Selected Research

G-Protein-Coupled Receptors (Receptors, G Protein Coupled)

1/2024Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A2 receptors.
12/2022Cryo-EM structure of the human adenosine A2B receptor-Gs signaling complex.
1/2021The G2A Receptor Deficiency Aggravates Atherosclerosis in Rats by Regulating Macrophages and Lipid Metabolism.
1/2021G Protein-Coupled Receptors in Osteoarthritis.
10/2018Design, synthesis, and biological evaluations of phenylpropiolic acid derivatives as novel GPR40 agonists.
1/2018Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses.
10/2017Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.
1/2017Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.
10/2013GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.
12/2012KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis.
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Mingyao Liu Research Topics

Disease

143Neoplasms (Cancer)
03/2024 - 10/2002
43Neoplasm Metastasis (Metastasis)
10/2023 - 10/2002
41Inflammation (Inflammations)
03/2024 - 01/2002
38Lung Injury
02/2024 - 12/2002
30Acute Lung Injury
02/2024 - 11/2004
27Prostatic Neoplasms (Prostate Cancer)
01/2022 - 12/2002
25Carcinogenesis
01/2024 - 10/2004
25Breast Neoplasms (Breast Cancer)
05/2020 - 01/2006
22Ischemia
03/2024 - 01/2002
22Reperfusion Injury
02/2024 - 01/2002
19Primary Graft Dysfunction
03/2024 - 04/2011
16Infections
02/2024 - 12/2004
14Lung Neoplasms (Lung Cancer)
11/2023 - 01/2011
10Virus Diseases (Viral Diseases)
11/2021 - 11/2014
9Pancreatic Neoplasms (Pancreatic Cancer)
01/2023 - 11/2008
9Carcinoma (Carcinomatosis)
01/2022 - 11/2010
8Fibrosis (Cirrhosis)
11/2023 - 09/2011
8Lung Diseases (Lung Disease)
06/2023 - 07/2009
8Edema (Dropsy)
01/2021 - 02/2003
7Colonic Neoplasms (Colon Cancer)
11/2023 - 06/2005
7Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 05/2011
7Brain Death (Brain Dead)
01/2022 - 10/2009
7Vesicular Stomatitis
10/2019 - 11/2014
7Pulmonary Edema
01/2018 - 08/2010
6Stomach Neoplasms (Stomach Cancer)
07/2024 - 12/2010
6COVID-19
12/2022 - 01/2020
6Bacterial Infections (Bacterial Infection)
01/2018 - 05/2007
6Wounds and Injuries (Trauma)
11/2017 - 01/2009
6Ventilator-Induced Lung Injury
12/2015 - 09/2002
6Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
08/2015 - 04/2003
5Autoimmune Diseases (Autoimmune Disease)
02/2024 - 01/2011
5Necrosis
12/2022 - 10/2003
5Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
08/2021 - 01/2011
5Bone Resorption
05/2017 - 11/2011
5Corneal Neovascularization
01/2014 - 01/2011
5Bronchiolitis
06/2012 - 11/2005
4Tyrosinemias (Tyrosinemia)
03/2024 - 11/2016
4Congenital Hypothyroidism (Cretinism)
03/2024 - 11/2021
4Hemorrhage
02/2024 - 01/2007
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
02/2024 - 03/2013
4B-Cell Lymphoma (Lymphoma, B Cell)
01/2024 - 06/2015
4Pathologic Processes
11/2023 - 06/2013
4Inborn Genetic Diseases (Disease, Hereditary)
03/2023 - 01/2018
4Adenocarcinoma
01/2023 - 12/2014
4Death (Near-Death Experience)
01/2021 - 03/2011
4Melanoma (Melanoma, Malignant)
12/2020 - 11/2008

Drug/Important Bio-Agent (IBA)

52Proteins (Proteins, Gene)FDA Link
03/2024 - 12/2002
20CytokinesIBA
01/2020 - 01/2002
19Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2016 - 11/2004
17Biomarkers (Surrogate Marker)IBA
01/2024 - 06/2006
15G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2024 - 10/2002
11LigandsIBA
01/2022 - 11/2008
11Hormones (Hormone)IBA
01/2022 - 03/2006
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2023 - 08/2009
9Prostaglandins DIBA
01/2021 - 03/2015
9Small Interfering RNA (siRNA)IBA
01/2019 - 04/2007
8Messenger RNA (mRNA)IBA
03/2024 - 04/2007
8Transcription Factors (Transcription Factor)IBA
01/2024 - 07/2002
8Phosphotransferases (Kinase)IBA
01/2022 - 05/2008
8Peptides (Polypeptides)IBA
01/2022 - 02/2009
8NF-kappa B (NF-kB)IBA
09/2015 - 06/2007
7Chimeric Antigen ReceptorsIBA
01/2024 - 01/2019
7Antiviral Agents (Antivirals)IBA
08/2023 - 11/2014
7Interleukin-10 (Interleukin 10)IBA
12/2022 - 05/2003
7Interleukin-6 (Interleukin 6)IBA
01/2021 - 12/2005
7LipopolysaccharidesIBA
05/2016 - 11/2006
6Therapeutic UsesIBA
02/2024 - 11/2012
6Histone Deacetylase InhibitorsIBA
01/2022 - 08/2014
6CateninsIBA
01/2022 - 03/2013
6InterferonsIBA
01/2019 - 11/2007
6EnzymesIBA
05/2018 - 01/2015
5RNA (Ribonucleic Acid)IBA
01/2024 - 03/2012
5Androgen Receptors (Androgen Receptor)IBA
08/2023 - 07/2008
5LipidsIBA
02/2023 - 06/2016
5ChemokinesIBA
01/2022 - 07/2011
5celastrolIBA
02/2020 - 03/2010
5Matrix Metalloproteinases (MMPs)IBA
01/2020 - 09/2011
5Kisspeptin-1 ReceptorsIBA
01/2018 - 10/2002
5Oxygen (Dioxygen)IBA
05/2017 - 01/2006
5fibroblast growth factor 21IBA
06/2016 - 01/2013
4Dinoprostone (PGE2)FDA Link
07/2024 - 01/2022
4STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
03/2024 - 02/2012
4Immune Checkpoint InhibitorsIBA
01/2024 - 01/2021
4Interleukin-17 (Interleukin 17)IBA
11/2023 - 03/2014
4KisspeptinsIBA
01/2022 - 01/2006
4Adenosine Diphosphate (ADP)IBA
01/2022 - 01/2018
4CollagenIBA
11/2021 - 01/2016
4serum P-component (CIt)IBA
10/2021 - 01/2016
4Glucose (Dextrose)FDA LinkGeneric
03/2021 - 12/2013
4Dextrans (Dextran)FDA Link
01/2021 - 12/2004
4Antineoplastic Agents (Antineoplastics)IBA
01/2021 - 05/2012

Therapy/Procedure

62Therapeutics
07/2024 - 01/2004
47Lung Transplantation
03/2024 - 12/2002
19Transplantation
03/2024 - 12/2008
17Immunotherapy
07/2024 - 01/2018
10Drug Therapy (Chemotherapy)
10/2023 - 03/2008
10Artificial Respiration (Mechanical Ventilation)
09/2021 - 12/2002
7Castration
01/2021 - 12/2016
6Oral Administration
02/2024 - 01/2018
5Organ Transplantation
02/2024 - 03/2004