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Cheng Liu Selected Research

Peptide Hydrolases (Proteases)

12/2018Multispectral Photoacoustic Imaging of Tumor Protease Activity with a Gold Nanocage-Based Activatable Probe.
4/2014The extrinsic coagulation cascade and tissue factor pathway inhibitor in macrophages: a potential therapeutic opportunity for atherosclerotic thrombosis.
1/2012Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug.
1/2011The legumain protease-activated auristatin prodrugs suppress tumor growth and metastasis without toxicity.
1/2006Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms.
9/2003Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.

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Cheng Liu Research Topics

Disease

216Neoplasms (Cancer)
05/2024 - 04/2002
39Neoplasm Metastasis (Metastasis)
04/2024 - 06/2003
34Liver Cirrhosis (Hepatic Cirrhosis)
01/2023 - 08/2002
29Inflammation (Inflammations)
05/2024 - 09/2003
29Breast Neoplasms (Breast Cancer)
12/2023 - 03/2007
28Thrombosis (Thrombus)
11/2023 - 08/2005
25Renal Cell Carcinoma (Grawitz Tumor)
10/2023 - 06/2006
23Infections
05/2024 - 07/2006
22Carcinogenesis
01/2024 - 07/2004
22Fibrosis (Cirrhosis)
11/2022 - 08/2002
20Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 12/2015
19Prostatic Neoplasms (Prostate Cancer)
01/2024 - 03/2012
17Hypoxia (Hypoxemia)
08/2022 - 01/2011
14Pain (Aches)
01/2023 - 03/2007
13Urinary Bladder Neoplasms (Bladder Cancer)
09/2023 - 12/2002
13Carcinoma (Carcinomatosis)
01/2022 - 10/2002
10Hepatocellular Carcinoma (Hepatoma)
03/2024 - 05/2007
10Osteosarcoma (Osteogenic Sarcoma)
06/2022 - 05/2011
10Necrosis
10/2021 - 10/2002
9Wounds and Injuries (Trauma)
04/2024 - 09/2003
9Chronic Hepatitis B
10/2023 - 08/2002
9Stomach Neoplasms (Stomach Cancer)
02/2023 - 02/2008
8COVID-19
02/2024 - 01/2021
8Leukemia
01/2022 - 03/2013
7Hemorrhage
11/2023 - 04/2014
7Squamous Cell Carcinoma of Head and Neck
03/2023 - 08/2017
6Osteoarthritis
12/2023 - 01/2006
6Cardiovascular Diseases (Cardiovascular Disease)
10/2023 - 01/2021
6Weight Loss (Weight Reduction)
04/2023 - 01/2017
6Atherosclerosis
04/2022 - 11/2003
6Lymphoma (Lymphomas)
01/2021 - 07/2004
6Adenoma (Adenomas)
01/2021 - 06/2017
6Glioblastoma (Glioblastoma Multiforme)
07/2020 - 04/2009
5Stress Urinary Incontinence
04/2024 - 06/2017
5Liver Neoplasms (Liver Cancer)
03/2024 - 01/2014
5Wilms Tumor (Wilm's Tumor)
12/2023 - 03/2013
5Ovarian Neoplasms (Ovarian Cancer)
11/2023 - 11/2016
5Atrial Fibrillation
01/2023 - 01/2019
5Neuroinflammatory Diseases
01/2023 - 01/2022
5Body Weight (Weight, Body)
01/2023 - 04/2011
5Sepsis (Septicemia)
12/2022 - 09/2003
5Melanoma (Melanoma, Malignant)
11/2022 - 04/2014
5Polyps
01/2020 - 01/2015

Drug/Important Bio-Agent (IBA)

62Proteins (Proteins, Gene)FDA Link
04/2024 - 04/2002
33Biomarkers (Surrogate Marker)IBA
03/2024 - 06/2013
32Messenger RNA (mRNA)IBA
11/2023 - 03/2007
21MicroRNAs (MicroRNA)IBA
11/2023 - 01/2015
18AntigensIBA
12/2023 - 10/2002
16RNA (Ribonucleic Acid)IBA
11/2023 - 01/2014
16Therapeutic UsesIBA
11/2023 - 05/2005
14Long Noncoding RNAIBA
03/2024 - 12/2017
14AntibodiesIBA
02/2024 - 07/2013
14Peptides (Polypeptides)IBA
01/2023 - 11/2003
11T-Cell Antigen Receptors (T-Cell Receptor)IBA
12/2023 - 07/2013
11LipidsIBA
12/2023 - 07/2004
11IntegrinsIBA
04/2023 - 06/2003
11Telomerase (Telomerase Reverse Transcriptase)IBA
02/2023 - 09/2004
11Dimethylnitrosamine (Nitrosodimethylamine)IBA
09/2022 - 10/2003
11CytokinesIBA
01/2022 - 02/2009
11Small Interfering RNA (siRNA)IBA
01/2020 - 08/2011
10ProdrugsIBA
02/2024 - 06/2003
9Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
04/2024 - 01/2018
9Doxorubicin (Adriamycin)FDA LinkGeneric
02/2024 - 10/2002
9Chimeric Antigen ReceptorsIBA
12/2023 - 01/2017
9CateninsIBA
02/2023 - 11/2016
9CollagenIBA
05/2022 - 08/2002
9Glucose (Dextrose)FDA LinkGeneric
01/2022 - 11/2013
8Carbon Tetrachloride (Tetrachloromethane)IBA
11/2022 - 12/2010
7Phosphotransferases (Kinase)IBA
12/2023 - 02/2014
7bufalinIBA
04/2023 - 01/2016
7EnzymesIBA
01/2020 - 07/2004
7asparaginylendopeptidase (legumain)IBA
07/2015 - 06/2003
6Estrogen ReceptorsIBA
12/2023 - 01/2018
6EpitopesIBA
11/2023 - 07/2013
6CreatinineIBA
10/2023 - 09/2004
6Transcription Factors (Transcription Factor)IBA
07/2023 - 04/2005
6Circular RNAIBA
07/2023 - 01/2020
6HLA-A Antigens (HLA-A)IBA
01/2022 - 08/2014
6Interleukin-6 (Interleukin 6)IBA
01/2021 - 08/2017
6Histones (Histone)IBA
01/2021 - 03/2007
6Peptide Hydrolases (Proteases)FDA Link
12/2018 - 09/2003
5Anti-Bacterial Agents (Antibiotics)IBA
03/2024 - 08/2011
5DNA (Deoxyribonucleic Acid)IBA
01/2024 - 06/2004
5Hemoglobins (Hemoglobin)IBA
10/2023 - 02/2017
5Antiviral Agents (Antivirals)IBA
09/2023 - 11/2003
5Membrane Proteins (Integral Membrane Proteins)IBA
01/2022 - 11/2012
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 12/2002
5Cisplatin (Platino)FDA LinkGeneric
01/2020 - 05/2011
5Transforming Growth Factors (Transforming Growth Factor)IBA
01/2020 - 01/2017

Therapy/Procedure

77Therapeutics
02/2024 - 10/2002
27Drug Therapy (Chemotherapy)
11/2023 - 05/2011
15Nephrectomy
10/2023 - 07/2013
15Thrombectomy
10/2023 - 01/2020
11Immunotherapy
06/2023 - 01/2009
8Radiotherapy
12/2023 - 03/2017
8Neoadjuvant Therapy
12/2023 - 12/2011
7Aftercare (After-Treatment)
05/2021 - 05/2005
5Transplantation
01/2023 - 10/2012
5Ligation
01/2022 - 04/2012
5Osteotomy
01/2020 - 01/2017