Richard F Little Selected Research

ibrutinib

1/2024	Follow-up from the A041202 study shows continued efficacy of ibrutinib regimens for older adults with CLL.
1/2022	Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial.
10/2021	Adverse event burden in older patients with CLL receiving bendamustine plus rituximab or ibrutinib regimens: Alliance A041202.
1/2019	Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia.
12/2018	Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.
12/2017	Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.

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Richard F Little Research Topics

Disease

29	Neoplasms (Cancer) 12/2023 - 01/2003
14	Lymphoma (Lymphomas) 01/2022 - 04/2002
13	Kaposi Sarcoma (Kaposi's Sarcoma) 11/2023 - 01/2003
12	Acquired Immunodeficiency Syndrome (AIDS) 11/2023 - 01/2003
7	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 04/2010
6	HIV Infections (HIV Infection) 11/2017 - 08/2010
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 09/2015
5	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020 - 04/2002
5	Castleman Disease (Castleman's Disease) 12/2013 - 03/2007
4	Hypertension (High Blood Pressure) 01/2024 - 05/2012
4	AIDS-Related Lymphoma (Lymphoma, AIDS Related) 01/2021 - 08/2005
4	Primary Effusion Lymphoma 01/2019 - 03/2007
3	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 04/2024 - 12/2018
3	Disease Progression 01/2022 - 12/2018
3	Multiple Myeloma 01/2021 - 08/2017
3	Leukemia 01/2020 - 11/2014
3	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2020 - 11/2013
3	Neutropenia 04/2014 - 06/2006
2	Atrial Fibrillation 01/2024 - 10/2021
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2023 - 01/2023
2	Infections 10/2021 - 08/2010
2	Thrombocytopenia (Thrombopenia) 01/2019 - 01/2017
2	Multi-centric Castleman's Disease 01/2019 - 12/2014
2	Hypoalbuminemia 01/2019 - 08/2010
2	Hodgkin Disease (Hodgkin's Disease) 01/2017 - 02/2015
2	Hand-Foot Syndrome 01/2017 - 04/2014
2	Hyponatremia 12/2013 - 08/2010
2	Opportunistic Infections (Opportunistic Infection) 04/2010 - 07/2006
2	AIDS-related Kaposi sarcoma 12/2007 - 06/2006
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2023
1	Frailty 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 11/2019
1	Chronic Disease (Chronic Diseases) 11/2018
1	Aspergillosis 12/2017
1	Residual Neoplasm 08/2017
1	Hyperhidrosis 08/2017
1	Nausea 08/2017
1	Anemia 08/2017
1	Communicable Diseases (Infectious Diseases) 01/2017

Drug/Important Bio-Agent (IBA)

10	Rituximab (Mabthera)FDA Link 04/2024 - 04/2010
7	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 04/2002
6	ibrutinibIBA 01/2024 - 12/2017
6	Etoposide (VP 16)FDA LinkGeneric 01/2020 - 04/2002
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 04/2002
6	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 04/2002
6	Prednisone (Sone)FDA LinkGeneric 01/2020 - 04/2002
4	CytokinesIBA 01/2019 - 06/2012
3	Bendamustine Hydrochloride FDA Link 04/2024 - 08/2017
3	trans-crotonin (CTN)IBA 01/2021 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 10/2020 - 06/2011
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 08/2010
3	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2018 - 11/2014
3	Biomarkers (Surrogate Marker)IBA 01/2017 - 08/2010
3	liposomal doxorubicin (Doxil)FDA Link 12/2014 - 01/2007
3	Interleukin-12 (IL 12)IBA 12/2007 - 06/2006
2	NivolumabIBA 11/2023 - 01/2023
2	Azacitidine (5 Azacytidine)FDA Link 01/2023 - 01/2022
2	AnthracyclinesIBA 01/2022 - 11/2014
2	RNA (Ribonucleic Acid)IBA 01/2021 - 06/2011
2	DNA (Deoxyribonucleic Acid)IBA 10/2020 - 06/2011
2	Interleukin-10 (Interleukin 10)IBA 01/2019 - 12/2013
2	InterleukinsIBA 01/2019 - 08/2010
2	alvocidib (flavopiridol)IBA 01/2018 - 09/2015
2	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2018 - 09/2015
2	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2018 - 09/2015
2	MicroRNAs (MicroRNA)IBA 06/2012 - 03/2007
2	AntibodiesIBA 08/2010 - 06/2010
2	AntigensIBA 08/2010 - 06/2010
1	entinostat (MS 275)IBA 12/2023
1	Histone Deacetylase InhibitorsIBA 12/2023
1	pembrolizumabIBA 12/2023
1	N 30IBA 01/2021
1	Melphalan (Alkeran)FDA LinkGeneric 01/2021
1	B7-H1 AntigenIBA 12/2020
1	Immune Checkpoint InhibitorsIBA 12/2020
1	Methotrexate (Mexate)FDA LinkGeneric 11/2020
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2020
1	MutS ProteinsIBA 10/2020
1	Co-Repressor ProteinsIBA 10/2020
1	MutL Protein Homolog 1IBA 10/2020
1	TensinsIBA 10/2020
1	fludarabineIBA 01/2019
1	Lenalidomide (CC 5013)FDA Link 01/2018
1	Agammaglobulinaemia Tyrosine KinaseIBA 12/2017
1	veliparibIBA 08/2017
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 08/2017
1	Alkylating AgentsIBA 08/2017
1	Growth Factor ReceptorsIBA 01/2017
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2017
1	Anti-Retroviral Agents (Antiretroviral Agents)IBA 01/2017
1	Lipase (Acid Lipase)FDA Link 01/2017

Therapy/Procedure

37	Therapeutics 12/2023 - 04/2002
10	Highly Active Antiretroviral Therapy (HAART) 02/2015 - 01/2003
7	Drug Therapy (Chemotherapy) 01/2020 - 04/2002
2	Precision Medicine 06/2023 - 01/2018
2	Investigational Therapies (Experimental Therapy) 01/2021 - 09/2007
2	Transplantation 10/2019 - 01/2013
1	Immunotherapy 11/2023
1	Hematopoietic Stem Cell Transplantation 01/2021
1	Stem Cell Transplantation 11/2018