Vitor A Lira Selected Research

Diabetes Mellitus

1/2018	Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.
1/2015	Enhanced skeletal muscle expression of extracellular superoxide dismutase mitigates streptozotocin-induced diabetic cardiomyopathy by reducing oxidative stress and aberrant cell signaling.

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Vitor A Lira Research Topics

Disease

5	Type 2 Diabetes Mellitus (MODY) 12/2022 - 08/2010
5	Obesity 11/2021 - 11/2017
3	Atrophy 11/2023 - 10/2015
3	Insulin Resistance 01/2021 - 08/2010
2	Neoplasms (Cancer) 12/2023 - 01/2023
2	Cachexia 01/2023 - 05/2014
2	Peripheral Arterial Disease 01/2022 - 12/2021
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2021 - 01/2015
2	Atherosclerotic Plaque (Atheroma) 01/2021 - 02/2014
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2018
2	Glucose Intolerance 01/2021 - 12/2018
2	Atherosclerosis 01/2021 - 02/2014
2	Inflammation (Inflammations) 01/2018 - 01/2015
2	Diabetes Mellitus 01/2018 - 01/2015
1	Lung Neoplasms (Lung Cancer) 12/2023
1	Wounds and Injuries (Trauma) 11/2023
1	Lewis Lung Carcinoma 01/2023
1	Ischemia 01/2022
1	Cardiomyopathies (Cardiomyopathy) 01/2022
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Drug Resistant Epilepsy 12/2018
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2018
1	Multiple Organ Failure (MODS) 12/2017
1	Endotoxemia 12/2017
1	Hypertension (High Blood Pressure) 01/2016
1	Muscle Weakness 10/2015
1	Fibrosis (Cirrhosis) 01/2015
1	Diabetic Cardiomyopathies 01/2015
1	Cardiomegaly (Heart Hypertrophy) 01/2015
1	Muscular Atrophy (Muscle Atrophy) 05/2014
1	Heart Failure 05/2014
1	Microvascular Rarefaction 05/2014

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 11/2023 - 05/2014
4	Messenger RNA (mRNA)IBA 01/2022 - 05/2014
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2022 - 02/2008
3	LipidsIBA 01/2021 - 01/2018
3	Insulin (Novolin)FDA Link 01/2021 - 08/2010
3	Superoxide DismutaseIBA 12/2017 - 05/2014
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 11/2023 - 05/2014
2	AntioxidantsIBA 01/2023 - 05/2014
2	NitritesIBA 12/2022 - 10/2022
2	NitratesIBA 12/2022 - 10/2022
2	CholesterolIBA 01/2021 - 02/2014
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2021
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2018
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2017 - 08/2010
1	Carbon MonoxideIBA 12/2023
1	Metalloproteases (Metalloproteinases)IBA 01/2022
1	DisintegrinsIBA 01/2022
1	Protein SIBA 11/2021
1	leupeptinIBA 01/2021
1	Cre recombinaseIBA 01/2021
1	Beclin-1IBA 01/2021
1	X-Box Binding Protein 1IBA 01/2021
1	Red Fluorescent ProteinIBA 01/2021
1	Ammonium Chloride (Sal Ammoniac)FDA Link 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	ChromatinIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA 01/2021
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021
1	Interleukin-1 (Interleukin 1)IBA 01/2021
1	Lipoproteins (Lipoprotein)IBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	Insulin ReceptorIBA 01/2021
1	SaltsIBA 01/2021
1	SolutionsIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	TunicamycinIBA 01/2021
1	SerpinsIBA 01/2021
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2021
1	ThapsigarginIBA 01/2021
1	Prokaryotic Initiation Factor-2IBA 01/2021
1	Green Fluorescent ProteinsIBA 01/2021
1	Activating Transcription Factor 6IBA 01/2021
1	Therapeutic UsesIBA 12/2018
1	PalmitatesIBA 01/2018
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2018
1	Dynamins (Dynamin)IBA 01/2018
1	CytokinesIBA 01/2018
1	LipopolysaccharidesIBA 12/2017
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 12/2017
1	fibroblast growth factor 21IBA 11/2017
1	Oxytocin (Pitocin)FDA LinkGeneric 01/2016
1	Hormones (Hormone)IBA 01/2016
1	Estrogen ReceptorsIBA 01/2016
1	tomatidineIBA 10/2015
1	Activating Transcription Factor 4IBA 10/2015
1	Ursolic AcidIBA 10/2015
1	Streptozocin (Streptozotocin)FDA Link 01/2015
1	GlucocorticoidsIBA 05/2014
1	EnzymesIBA 05/2014
1	MM Form Creatine KinaseIBA 05/2014
1	CalsequestrinIBA 05/2014
1	Nitric Oxide DonorsIBA 05/2014
1	S-NitrosoglutathioneIBA 05/2014
1	oxidized low density lipoproteinIBA 02/2014

Therapy/Procedure

5	Therapeutics 12/2023 - 02/2008
1	Surgical Amputation (Amputations) 12/2021