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Jacqueline M Linehan Selected Research

(ctm)PrP

1/2013Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.

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Jacqueline M Linehan Research Topics

Disease

22Prion Diseases (Transmissible Spongiform Encephalopathies)
01/2020 - 05/2004
13Infections
03/2014 - 08/2004
11Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
06/2015 - 12/2002
9Bovine Spongiform Encephalopathy (Mad Cow Disease)
06/2015 - 12/2002
5Scrapie
11/2013 - 05/2004
4Kuru
06/2015 - 03/2008
4Acquired CJD
03/2008 - 12/2002
3Neurodegenerative Diseases (Neurodegenerative Disease)
03/2016 - 01/2013
3Disease Progression
03/2014 - 09/2006
3Sporadic Creutzfeldt-Jakob Disease
09/2008 - 09/2006
2Chronic Wasting Disease
01/2022 - 10/2010
2Alzheimer Disease (Alzheimer's Disease)
04/2012 - 01/2012
1Amyloid Plaque
11/2013
1Diarrhea
11/2013
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
11/2013
1Tauopathies
11/2013
1Proteostasis Deficiencies
01/2013
1Trisomy (Trisomies)
04/2012
1Genetic Predisposition to Disease (Genetic Predisposition)
09/2008

Drug/Important Bio-Agent (IBA)

26PrionsIBA
01/2022 - 12/2002
23Prion ProteinsIBA
01/2020 - 12/2002
3Methionine (L-Methionine)FDA Link
10/2010 - 12/2002
2Peptide Hydrolases (Proteases)FDA Link
01/2013 - 06/2006
2Codon (Codons)IBA
09/2006 - 12/2002
1UbiquitinIBA
03/2016
1Proteasome Endopeptidase Complex (Proteasome)IBA
03/2016
1Proteins (Proteins, Gene)FDA Link
03/2016
1(ctm)PrPIBA
01/2013
1tau Proteins (tau Protein)IBA
04/2012
1Monoclonal AntibodiesIBA
01/2012
1Valine (L-Valine)FDA Link
10/2010
1Quinacrine (Mepacrine)IBA
12/2006
1Protein Isoforms (Isoforms)IBA
06/2006
1Proline (L-Proline)FDA Link
06/2006
1Leucine (L-Leucine)FDA Link
06/2006

Therapy/Procedure

1Therapeutics
01/2012
1Blood Transfusion (Blood Transfusions)
12/2006
1Investigational Therapies (Experimental Therapy)
12/2006
1Tonsillectomy
10/2004