Olivier Lichtarge Selected Research

G-Protein-Coupled Receptors (Receptors, G Protein Coupled)

12/2021	Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors.
1/2018	Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling.

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Olivier Lichtarge Research Topics

Disease

17	Neoplasms (Cancer) 05/2024 - 02/2015
4	Squamous Cell Carcinoma of Head and Neck 01/2023 - 02/2015
3	Head and Neck Neoplasms (Head and Neck Cancer) 11/2022 - 02/2015
3	COVID-19 11/2021 - 01/2021
2	Carcinogenesis 02/2024 - 02/2014
2	Type 2 Diabetes Mellitus (MODY) 10/2023 - 01/2018
2	Neoplasm Metastasis (Metastasis) 01/2021 - 10/2016
2	Breast Neoplasms (Breast Cancer) 01/2019 - 01/2018
2	Schizophrenia (Dementia Praecox) 01/2019 - 06/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 01/2017
2	Malaria 01/2018 - 08/2014
2	Brain Diseases (Brain Disorder) 02/2013 - 08/2009
1	Autism Spectrum Disorder 01/2021
1	Intellectual Disability (Idiocy) 01/2021
1	Infections 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Bipolar Disorder (Manic Depressive Psychosis) 12/2019
1	Psychotic Disorders (Schizoaffective Disorder) 12/2019
1	Uveal melanoma 10/2019
1	Mucopolysaccharidosis III (Sanfilippo Syndrome) 01/2019
1	Hyperhomocysteinemia 01/2019
1	Homocystinuria 01/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2018
1	Triple Negative Breast Neoplasms 01/2018
1	Sclerosis 01/2018
1	Levin type Osteogenesis imperfecta 01/2018
1	Asthma (Bronchial Asthma) 01/2017
1	Job Syndrome (Hyper-IgE Syndrome) 12/2016
1	Carcinoma (Carcinomatosis) 10/2016
1	Ovarian Neoplasms (Ovarian Cancer) 10/2015
1	Osteogenesis Imperfecta (Lobstein Disease) 01/2014
1	Desmosterolosis 07/2011

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2014
4	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 02/2015
4	DNA (Deoxyribonucleic Acid)IBA 08/2021 - 03/2019
4	Phosphotransferases (Kinase)IBA 01/2021 - 02/2015
3	RNA (Ribonucleic Acid)IBA 05/2024 - 01/2019
3	VaccinesIBA 11/2021 - 01/2021
3	LigandsIBA 12/2019 - 09/2006
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2021 - 01/2018
2	Amino Acids FDA Link 12/2021 - 02/2013
2	MicroRNAs (MicroRNA)IBA 10/2019 - 01/2019
2	NucleotidesIBA 01/2019 - 01/2016
2	EnzymesIBA 01/2019 - 07/2011
2	Hemin (Panhematin)FDA Link 01/2018 - 08/2014
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 05/2024
1	Transcription Factors (Transcription Factor)IBA 02/2024
1	Glucagon-Like Peptide-1 ReceptorIBA 10/2023
1	Docetaxel (Taxotere)FDA Link 11/2022
1	GTP-Binding Proteins (G-Protein)IBA 12/2021
1	ArrestinsIBA 12/2021
1	MethyltransferasesIBA 08/2021
1	PPAR gammaIBA 08/2021
1	Adenosine Diphosphate Ribose (ADP-Ribose)IBA 01/2021
1	poly ADP-ribose glycohydrolaseIBA 01/2021
1	DNA-Activated Protein KinaseIBA 01/2021
1	Glycoside Hydrolases (Endoglycosidases)IBA 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2021
1	ApolipoproteinsIBA 01/2021
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 10/2019
1	Deubiquitinating EnzymesIBA 10/2019
1	ParaffinIBA 03/2019
1	Formaldehyde (Formol)FDA Link 03/2019
1	Checkpoint Kinase 2IBA 01/2019
1	HomocysteineIBA 01/2019
1	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 01/2019
1	CystathionineIBA 01/2019
1	alpha-N-acetyl-D-glucosaminidase (alpha-N-acetylglucosaminidase)IBA 01/2019
1	Ligases (Synthetase)IBA 11/2018
1	Transfer RNA (tRNA)IBA 11/2018
1	Antimalarials (Antimalarial Agents)IBA 01/2018
1	Melatonin Receptors (Melatonin Receptor)IBA 01/2018
1	AnoctaminsIBA 01/2018
1	TransferasesIBA 01/2018
1	Tyrosine (L-Tyrosine)FDA Link 01/2018
1	artemisinin (artemisinine)IBA 01/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018
1	A Kinase Anchor ProteinsIBA 01/2018
1	IronIBA 01/2018
1	Glutathione (Reduced Glutathione)IBA 01/2018
1	MT2 Melatonin ReceptorIBA 01/2018
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2017
1	Codon (Codons)IBA 01/2017
1	Cyclin D1IBA 10/2016
1	Cyclin-Dependent Kinase Inhibitor p16IBA 10/2016
1	CytokinesIBA 10/2015
1	nutlin 3IBA 10/2015
1	Dopamine (Intropin)FDA LinkGeneric 06/2015
1	PlatinumIBA 04/2015
1	adavosertibIBA 02/2015
1	ArtesunateIBA 08/2014
1	ras ProteinsIBA 02/2014
1	2-oxoglutarate 3-dioxygenase prolineIBA 01/2014
1	DesmosterolIBA 07/2011
1	CholesterolIBA 07/2011

Therapy/Procedure

7	Therapeutics 11/2022 - 02/2015
1	Chemoradiotherapy 11/2022