Siqi Li Selected Research

Vaccines

3/2024	Design, synthesis, and antiviral activity of 1-aryl-4-arylmethylpiperazine derivatives as Zika virus inhibitors with broad antiviral spectrum.
2/2024	MecVax supplemented with CFA MEFA-II induces functional antibodies against 12 adhesins (CFA/I, CS1-CS7, CS12, CS14, CS17, and CS21) and 2 toxins (STa, LT) of enterotoxigenic Escherichia coli (ETEC).
11/2023	Protein-based vaccine candidate MecVax broadly protects against enterotoxigenic Escherichia coli intestinal colonization in a rabbit model.
11/2023	A broadly immunogenic polyvalent Shigella multiepitope fusion antigen protein protects against Shigella sonnei and Shigella flexneri lethal pulmonary challenges in mice.
10/2023	A Polyvalent Adhesin-Toxoid Multiepitope-Fusion-Antigen-Induced Functional Antibodies against Five Enterotoxigenic Escherichia coli Adhesins (CS7, CS12, CS14, CS17, and CS21) but Not Enterotoxins (LT and STa).
1/2023	Polyvalent Protein Adhesin MEFA-II Induces Functional Antibodies against Enterotoxigenic Escherichia coli (ETEC) Adhesins CS7, CS12, CS14, CS17, and CS21 and Heat-Stable Toxin (STa).
1/2022	Multiepitope Fusion Antigen: MEFA, an Epitope- and Structure-Based Vaccinology Platform for Multivalent Vaccine Development.
1/2022	Intramuscularly Administered Enterotoxigenic Escherichia coli (ETEC) Vaccine Candidate MecVax Prevented H10407 Intestinal Colonization in an Adult Rabbit Colonization Model.

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Siqi Li Research Topics

Disease

39	Neoplasms (Cancer) 05/2024 - 07/2010
21	Inflammation (Inflammations) 05/2024 - 12/2019
9	Fibrosis (Cirrhosis) 12/2023 - 08/2017
8	Infections 12/2023 - 01/2017
7	Neoplasm Metastasis (Metastasis) 03/2024 - 09/2018
7	Diarrhea 02/2024 - 01/2022
7	Hypoxia (Hypoxemia) 01/2022 - 10/2016
6	Obesity 03/2024 - 06/2020
6	Chronic Obstructive Pulmonary Disease (COPD) 03/2024 - 11/2021
5	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 01/2020
5	Mitochondrial Diseases (Mitochondrial Disease) 10/2023 - 01/2020
5	Sepsis (Septicemia) 10/2023 - 01/2006
5	Triple Negative Breast Neoplasms 01/2022 - 01/2020
4	Insulin Resistance 03/2024 - 01/2021
4	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2024 - 01/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 07/2021
4	Colorectal Neoplasms (Colorectal Cancer) 12/2022 - 01/2016
4	Atrial Fibrillation 12/2022 - 06/2020
4	Myocarditis (Carditis) 01/2022 - 08/2020
3	Adenocarcinoma of Lung 03/2024 - 02/2022
3	Metabolic Diseases (Metabolic Disease) 03/2024 - 01/2019
3	Periodontitis 12/2023 - 01/2022
3	Breast Neoplasms (Breast Cancer) 01/2023 - 01/2021
3	Carcinogenesis 12/2022 - 01/2020
3	Atherosclerosis 10/2022 - 12/2020
3	Body Weight (Weight, Body) 07/2022 - 02/2018
3	Aortic Aneurysm (Aneurysm, Aortic) 01/2022 - 12/2020
3	Anastomotic Leak 12/2021 - 01/2021
3	Pneumothorax 12/2021 - 01/2021
3	Esophageal atresia with or without tracheoesophageal fistula 12/2021 - 01/2021
2	Choroidal Neovascularization 05/2024 - 03/2024
2	Necrosis 05/2024 - 06/2023
2	Sarcopenia 04/2024 - 01/2024
2	Vascular Remodeling 12/2023 - 05/2022
2	Bone Resorption 12/2023 - 01/2022
2	Peri-Implantitis 12/2023 - 01/2022
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2023 - 05/2022
2	Colitis 11/2023 - 11/2021
2	Neuroblastoma 11/2023 - 01/2023
2	Sepsis-Associated Encephalopathy 10/2023 - 11/2022
2	Neuroinflammatory Diseases 10/2023 - 11/2022
2	Glucose Intolerance 01/2023 - 01/2023
2	Malaria 01/2023 - 01/2022
2	Cognitive Dysfunction 12/2022 - 02/2022

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 03/2024 - 11/2015
9	CytokinesIBA 01/2024 - 12/2020
8	VaccinesIBA 03/2024 - 01/2022
8	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2021
6	LigandsIBA 12/2023 - 01/2021
5	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 01/2017
5	Oxygen (Dioxygen)IBA 02/2024 - 10/2016
5	AntibodiesIBA 10/2023 - 01/2022
4	Immune Checkpoint InhibitorsIBA 01/2024 - 08/2020
4	LipidsIBA 10/2023 - 11/2015
4	Angiotensin IIIBA 01/2022 - 08/2017
3	Protein Isoforms (Isoforms)IBA 03/2024 - 12/2018
3	Enterotoxins (Enterotoxin)IBA 02/2024 - 01/2022
3	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 12/2023 - 06/2013
3	CollagenIBA 12/2023 - 08/2017
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/2023 - 01/2021
3	Therapeutic UsesIBA 11/2023 - 11/2021
3	AntigensIBA 11/2023 - 01/2022
3	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 09/2015
3	LipopolysaccharidesIBA 10/2023 - 01/2006
3	Urethane (Ethyl Carbamate)IBA 01/2022 - 01/2020
3	CarcinogensIBA 01/2022 - 01/2020
3	Long Noncoding RNAIBA 01/2022 - 10/2021
3	CalciumIBA 10/2021 - 01/2018
2	Granzymes (Granzyme)IBA 05/2024 - 03/2024
2	IronIBA 05/2024 - 09/2023
2	Circular RNAIBA 04/2024 - 01/2020
2	C-Reactive ProteinIBA 01/2024 - 01/2022
2	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 12/2023 - 01/2021
2	EnzymesIBA 12/2023 - 01/2022
2	cenicrivirocIBA 12/2023 - 11/2022
2	Caspase 1 (ICE Protease)IBA 12/2023 - 10/2023
2	omega-Chloroacetophenone (Mace)IBA 12/2023 - 01/2023
2	Cadherins (E-Cadherin)IBA 12/2023 - 09/2018
2	Interleukin-6 (Interleukin 6)IBA 12/2023 - 11/2021
2	CarbonIBA 11/2023 - 01/2016
2	baicaleinIBA 11/2023 - 11/2021
2	Combined VaccinesIBA 11/2023 - 01/2022
2	HydrogenIBA 10/2023 - 11/2022
2	hydrogen rich salineIBA 10/2023 - 11/2022
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2023 - 12/2021
2	Hematoxylin (Haematoxylon)IBA 05/2023 - 11/2021
2	Eosine Yellowish-(YS) (Eosin)IBA 05/2023 - 11/2021
2	Triglycerides (Triacylglycerol)IBA 01/2023 - 12/2022
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2023 - 01/2021
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2023 - 01/2019
2	Indicators and Reagents (Reagents)IBA 12/2022 - 06/2020
2	Messenger RNA (mRNA)IBA 12/2022 - 01/2006
2	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2022 - 12/2020

Therapy/Procedure

18	Therapeutics 05/2024 - 09/2015
8	Immunotherapy 03/2024 - 01/2022
6	Drug Therapy (Chemotherapy) 10/2023 - 01/2016
4	Ligation 12/2023 - 01/2022
3	Radiotherapy 03/2024 - 10/2023
3	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2023 - 01/2016
2	Radioimmunotherapy 03/2024 - 01/2023