James B Leverenz Selected Research

DNA-Binding Proteins (DNA Binding Protein)

1/2023	Dementia with Lewy bodies: Impact of co-pathologies and implications for clinical trial design.
8/2015	R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study.

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James B Leverenz Research Topics

Disease

73	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 01/2003
35	Parkinson Disease (Parkinson's Disease) 01/2021 - 08/2006
32	Dementia (Dementias) 02/2024 - 08/2006
26	Cognitive Dysfunction 01/2023 - 01/2009
9	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2024 - 08/2006
9	Amyloid Plaque 01/2020 - 04/2011
7	Disease Progression 01/2020 - 08/2006
4	Lewy Body Disease (Lewy Body Dementia) 01/2023 - 01/2018
4	Parkinsonian Disorders (Parkinsonism) 01/2021 - 09/2007
3	Inflammation (Inflammations) 01/2023 - 03/2015
3	Synucleinopathies 01/2017 - 01/2012
3	Frontotemporal Dementia (Semantic Dementia) 12/2014 - 08/2003
3	Multiple System Atrophy 02/2012 - 03/2011
3	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 03/2011 - 09/2007
2	Insulin Resistance 01/2023 - 06/2006
2	COVID-19 03/2021 - 01/2021
2	Neurologic Manifestations (Neurological Manifestations) 03/2021 - 01/2021
2	Down Syndrome (Down's Syndrome) 01/2021 - 01/2020
2	REM Sleep Behavior Disorder 01/2018 - 07/2017
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 02/2012 - 09/2007
2	Seizures (Absence Seizure) 04/2010 - 11/2004
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2008 - 09/2007
1	Mixed Dementias 02/2024
1	Hemorrhage 02/2024
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 02/2024
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2023
1	Hypertension (High Blood Pressure) 01/2023
1	Type 2 Diabetes Mellitus (MODY) 10/2022
1	Hallucinations (Hallucination) 03/2022
1	Neurobehavioral Manifestations 01/2021
1	Anosmia 01/2018
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2017
1	Movement Disorders (Movement Disorder) 10/2016
1	Death (Near-Death Experience) 06/2016
1	Ganglion Cysts (Ganglion) 01/2016

Drug/Important Bio-Agent (IBA)

42	Biomarkers (Surrogate Marker)IBA 03/2024 - 08/2006
22	Proteins (Proteins, Gene)FDA Link 03/2021 - 08/2006
17	Amyloid (Amyloid Fibrils)IBA 02/2024 - 01/2012
11	Apolipoproteins E (ApoE)IBA 01/2021 - 10/2007
11	SynucleinsIBA 12/2019 - 03/2011
8	ApolipoproteinsIBA 04/2018 - 01/2003
6	alpha-SynucleinIBA 04/2014 - 09/2007
4	Amyloid beta-PeptidesIBA 08/2015 - 12/2006
3	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2012
3	RNA (Ribonucleic Acid)IBA 10/2021 - 01/2021
3	LipidsIBA 01/2021 - 01/2019
3	Retinaldehyde (Retinal)IBA 01/2020 - 01/2016
3	Presenilin-1IBA 04/2019 - 04/2010
3	Phosphotransferases (Kinase)IBA 01/2018 - 07/2013
3	MicroRNAs (MicroRNA)IBA 01/2018 - 08/2013
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2023 - 08/2015
2	Insulin (Novolin)FDA Link 10/2022 - 06/2011
2	Adenosine Diphosphate (ADP)IBA 03/2022 - 01/2021
2	Antiviral Agents (Antivirals)IBA 03/2021 - 01/2021
2	FurinIBA 03/2021 - 01/2021
2	Presenilin-2IBA 04/2019 - 04/2010
2	Carrier Proteins (Binding Protein)IBA 01/2019 - 09/2015
2	tau Proteins (tau Protein)IBA 01/2019 - 05/2011
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2018 - 03/2008
2	Levodopa (L Dopa)FDA LinkGeneric 11/2017 - 10/2016
2	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 06/2016 - 08/2015
2	HaptoglobinsIBA 01/2016 - 09/2015
2	Apolipoprotein E4IBA 08/2015 - 10/2012
2	DNA (Deoxyribonucleic Acid)IBA 06/2015 - 09/2007
2	F2-Isoprostanes (F2 Isoprostanes)IBA 09/2014 - 06/2014
2	Free RadicalsIBA 09/2014 - 06/2014
2	Peptides (Polypeptides)IBA 08/2013 - 10/2012
2	Glutamic Acid (Glutamate)FDA Link 11/2011 - 04/2009
2	Detergents (Detergent)IBA 07/2010 - 04/2009
2	UbiquitinIBA 05/2008 - 09/2007
2	GlucocorticoidsIBA 06/2006 - 02/2005
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2023
1	Telmisartan (Micardis)FDA Link 01/2023
1	HDL-triglycerideIBA 01/2023
1	CholesterolIBA 01/2023
1	Pioglitazone (Actos)FDA Link 10/2022
1	Glipizide (Glucotrol)FDA LinkGeneric 10/2022
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2022
1	SecretagoguesIBA 10/2022
1	SodiumIBA 01/2022
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2022
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022
1	Chemokine CX3CL1IBA 01/2022
1	rasagiline (Azilect)FDA Link 01/2021
1	Zonisamide (Zonegran)FDA LinkGeneric 01/2021
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	FibrinIBA 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2019
1	Poly Adenosine Diphosphate RiboseIBA 11/2018
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2018
1	Leucine (L-Leucine)FDA Link 01/2018
1	HomocysteineIBA 11/2017
1	3-Iodobenzylguanidine (Iobenguane)IBA 07/2017
1	Neuroprotective AgentsIBA 01/2017
1	SilverIBA 06/2016

Therapy/Procedure

7	Therapeutics 02/2024 - 01/2017
1	Activities of Daily Living (ADL) 01/2021
1	Precision Medicine 12/2019