Henry A Lester Selected Research

Cholinergic Agents (Cholinergics)

1/2018	Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.
3/2015	Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.
10/2012	Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations.
8/2012	Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction.
1/2010	Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Henry A Lester Research Topics

Disease

13	Tobacco Use Disorder (Nicotine Dependence) 10/2019 - 11/2004
8	Parkinson Disease (Parkinson's Disease) 01/2019 - 10/2003
8	Autosomal Dominant Nocturnal Frontal Lobe Epilepsy 01/2016 - 07/2003
6	Seizures (Absence Seizure) 03/2009 - 04/2003
3	Neuroblastoma 03/2016 - 12/2009
3	Alzheimer Disease (Alzheimer's Disease) 02/2013 - 12/2005
3	Hypothermia 01/2013 - 09/2003
3	Tremor (Tremors) 01/2010 - 10/2003
2	Schizophrenia (Dementia Praecox) 09/2014 - 03/2009
2	Pain (Aches) 04/2011 - 03/2009
1	Major Depressive Disorder (Major Depressive Disorders) 01/2023
1	COVID-19 01/2021
1	Severe Acute Respiratory Syndrome 01/2021
1	Mental Disorders (Mental Disorder) 12/2020
1	Chronic Pain 11/2020
1	Synucleinopathies 01/2018
1	Wounds and Injuries (Trauma) 05/2015
1	Hyperalgesia 05/2015
1	Movement Disorders (Movement Disorder) 03/2015
1	Alcoholism (Alcohol Abuse) 02/2014
1	Lung Neoplasms (Lung Cancer) 02/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2013
1	Ganglion Cysts (Ganglion) 09/2012
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2011
1	Nervous System Diseases (Neurological Disorders) 04/2011
1	Acquired Immunodeficiency Syndrome (AIDS) 06/2010
1	Catalepsy 01/2010
1	Epilepsy (Aura) 03/2009
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 03/2009
1	Autistic Disorder (Autism) 03/2009
1	Ataxia (Dyssynergia) 03/2005
1	Motor Disorders 03/2005
1	Body Weight (Weight, Body) 03/2005
1	Tardive Dyskinesia 02/2005
1	Dyskinesias (Dyskinesia) 02/2005
1	Hypokinesia (Bradykinesia) 10/2003
1	Deafness (Deaf Mutism) 03/2003

Drug/Important Bio-Agent (IBA)

24	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 11/2020 - 04/2003
15	Nicotine FDA Link 01/2019 - 04/2003
5	Cholinergic Agents (Cholinergics)IBA 01/2018 - 01/2010
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2005
4	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 10/2003
4	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016 - 07/2003
3	LigandsIBA 11/2020 - 10/2012
2	Cholinergic ReceptorsIBA 01/2016 - 03/2009
2	gamma-Aminobutyric Acid (GABA)IBA 12/2009 - 03/2005
2	GABA Plasma Membrane Transport ProteinsIBA 12/2009 - 03/2005
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2023
1	Serotonin (5 Hydroxytryptamine)IBA 12/2020
1	Analgesics (Analgesic Drugs)IBA 11/2020
1	Opioid Analgesics (Opioids)IBA 11/2020
1	cytisineIBA 10/2019
1	Nicotinic AgonistsIBA 01/2018
1	Menthol FDA Link 03/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 02/2013
1	Memantine (Namenda)FDA Link 02/2013
1	N-Methylaspartate (NMDA)IBA 02/2013
1	Leucine (L-Leucine)FDA Link 01/2013
1	Valine (L-Valine)FDA Link 01/2013
1	SodiumIBA 09/2012
1	Pheromones (Semiochemicals)IBA 09/2012
1	Neuroprotective AgentsIBA 06/2012
1	PHluorinIBA 09/2011
1	Amino Acids FDA Link 07/2010
1	QuinpiroleIBA 01/2010
1	CationsIBA 03/2009
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 03/2009
1	Therapeutic UsesIBA 03/2009
1	ElementsIBA 09/2007
1	MecamylamineIBA 09/2007
1	Carbamazepine (Tegretol)FDA LinkGeneric 09/2007
1	Sodium Channel BlockersIBA 09/2007
1	antineoplaston A10 (A 10)IBA 12/2005
1	Peptides (Polypeptides)IBA 12/2005
1	Peptide Hydrolases (Proteases)FDA Link 12/2005
1	Amyloid beta-PeptidesIBA 12/2005
1	Amyloid (Amyloid Fibrils)IBA 12/2005
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2005
1	Flunitrazepam (Rohypnol)IBA 03/2005
1	GTP Phosphohydrolases (GTPases)IBA 02/2005
1	Antipsychotic Agents (Antipsychotics)IBA 02/2005
1	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 02/2005
1	Dopamine Receptors (Dopamine Receptor)IBA 02/2005
1	Levodopa (L Dopa)FDA LinkGeneric 02/2005
1	regulator of g-protein signaling 9IBA 02/2005
1	Glutamic Acid (Glutamate)FDA Link 07/2003
1	Tacrine (Cognex)FDA Link 04/2003
1	Galantamine (Galanthamine)FDA LinkGeneric 04/2003
1	Potassium Channels (Potassium Channel)IBA 03/2003

Therapy/Procedure

2	Therapeutics 01/2018 - 06/2010
1	Analgesia 05/2015
1	Injections 11/2007
1	Transplantation 10/2003