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Barbara Lelli Selected Research

Peptides (Polypeptides)

1/2019Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias.
1/2015Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.
6/2013Cancer selectivity of tetrabranched neurotensin peptides is generated by simultaneous binding to sulfated glycosaminoglycans and protein receptors.
4/2013Nanoparticles exposing neurotensin tumor-specific drivers.
4/2011Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides.
4/2010Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.
9/2007Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting.
4/2006Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo.

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Barbara Lelli Research Topics

Disease

8Neoplasms (Cancer)
01/2015 - 09/2007
1Leukemia
01/2019
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2015
1Rheumatoid Arthritis
06/2014
1Melanoma (Melanoma, Malignant)
06/2014
1Carcinogenesis
06/2012
1Prostatic Neoplasms (Prostate Cancer)
06/2012
1Rhabdomyosarcoma
04/2011
1Colonic Neoplasms (Colon Cancer)
04/2011
1Schizophrenia (Dementia Praecox)
08/2010
1Anthrax
04/2006

Drug/Important Bio-Agent (IBA)

8Peptides (Polypeptides)IBA
01/2019 - 04/2006
6NeurotensinIBA
01/2015 - 09/2007
2Liposomes (Liposome)IBA
04/2013 - 04/2011
2LigandsIBA
06/2012 - 08/2010
1Factor XII (Hageman Factor)IBA
01/2019
1PotassiumIBA
01/2019
1IntegrinsIBA
01/2019
1Chemokine ReceptorsIBA
01/2019
1Methotrexate (Mexate)FDA LinkGeneric
01/2015
1tumor-specific tetrabranched peptide NT4IBA
01/2015
1GemcitabineFDA Link
01/2015
1Adalimumab (Humira)FDA Link
06/2014
1peptide AIBA
06/2014
1Monoclonal AntibodiesIBA
06/2014
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
06/2014
1Proteins (Proteins, Gene)FDA Link
06/2013
1LDL Receptors (LDL Receptor)IBA
06/2013
1Heparin (Liquaemin)FDA LinkGeneric
06/2013
1GlycosaminoglycansIBA
06/2013
1cholanic acidIBA
06/2012
1EphA2 ReceptorIBA
06/2012
1EphrinsIBA
06/2012
1Neurotensin Receptors (Neurotensin Receptor)IBA
04/2011
11,2-oleoylphosphatidylcholine (DOPC)IBA
04/2011
1Serine (L-Serine)FDA Link
08/2010
1D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA
08/2010
1Neoplasm Antigens (Tumor Antigens)IBA
04/2010
1Peptide Receptors (Peptide Receptor)IBA
04/2010
1neurotensin (9-13)IBA
09/2007
1NeuropeptidesIBA
09/2007
1AntigensIBA
04/2006

Therapy/Procedure

3Therapeutics
01/2015 - 09/2007
1Precision Medicine
06/2013