Marcel Leist Selected Research

Therapeutics

7/2005	Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.
7/2002	Burning up TNF toxicity for cancer therapy.

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Marcel Leist Research Topics

Disease

21	Parkinson Disease (Parkinson's Disease) 01/2023 - 02/2004
7	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2022 - 04/2003
6	Neoplasms (Cancer) 12/2022 - 07/2002
6	Inflammation (Inflammations) 01/2020 - 08/2004
5	Alzheimer Disease (Alzheimer's Disease) 10/2018 - 05/2006
4	Infections 01/2021 - 05/2002
3	Schizophrenia (Dementia Praecox) 09/2023 - 01/2006
3	Stroke (Strokes) 04/2008 - 05/2006
3	Ischemia 03/2007 - 11/2004
2	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 10/2022
2	Hypersensitivity (Allergy) 01/2022 - 01/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2020
2	Glioblastoma (Glioblastoma Multiforme) 03/2019 - 12/2002
2	Disease Progression 07/2014 - 04/2003
2	Infarction (Infarctions) 03/2007 - 11/2004
2	Hypoxia (Hypoxemia) 05/2006 - 11/2004
2	Necrosis 03/2005 - 01/2004
2	Huntington Disease (Huntington's Disease) 05/2004 - 04/2003
1	Acute Liver Failure (Fulminant Hepatic Failure) 11/2023
1	Psychotic Disorders (Schizoaffective Disorder) 09/2023
1	Cardiotoxicity 08/2023
1	Laminopathies 12/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 12/2022
1	Chromosome Aberrations (Chromosome Abnormalities) 11/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2022
1	Hyperalgesia 01/2022
1	Neuroblastoma 01/2021
1	Infectious Arthritis (Septic Arthritis) 01/2021
1	Leukemia 06/2020
1	COVID-19 01/2020
1	Poisoning 01/2020
1	Hepatitis 01/2020
1	Metabolic Diseases (Metabolic Disease) 01/2020
1	Rupture 03/2019
1	Brain Neoplasms (Brain Tumor) 01/2018

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2002
6	Erythropoietin FDA Link 04/2008 - 05/2003
5	SynucleinsIBA 01/2021 - 12/2011
5	alpha-SynucleinIBA 01/2019 - 12/2011
4	CytokinesIBA 01/2020 - 05/2003
3	PesticidesIBA 01/2021 - 03/2017
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2004
3	Peptides (Polypeptides)IBA 03/2019 - 04/2007
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2017 - 08/2015
3	Interleukin-6 (Interleukin 6)IBA 04/2007 - 08/2004
3	asialoerythropoietinIBA 11/2004 - 05/2003
2	Antipsychotic Agents (Antipsychotics)IBA 09/2023 - 01/2006
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2023 - 05/2006
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 11/2010
2	Intrinsically Disordered ProteinsIBA 01/2021 - 12/2017
2	IronIBA 01/2020 - 07/2014
2	XenobioticsIBA 01/2020 - 12/2014
2	Dopamine (Intropin)FDA LinkGeneric 10/2018 - 12/2007
2	Amyloid (Amyloid Fibrils)IBA 10/2018 - 08/2014
2	EnzymesIBA 10/2018 - 12/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 03/2007
2	2,6-dinitrotoluene (DNT)IBA 07/2014 - 01/2014
2	Amyloid beta-PeptidesIBA 04/2009 - 04/2007
2	N-Methylaspartate (NMDA)IBA 03/2007 - 05/2006
2	Phosphotransferases (Kinase)IBA 03/2005 - 08/2004
2	3,9-bis((ethylthio)methyl)-K-252aIBA 03/2005 - 08/2004
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 04/2003 - 12/2002
1	Acetaminophen (Paracetamol)FDA LinkGeneric 11/2023
1	proline transporterIBA 09/2023
1	Proline (L-Proline)FDA Link 09/2023
1	Ketamine FDA LinkGeneric 09/2023
1	TeratogensIBA 08/2023
1	Lamin Type B (Lamin B)IBA 12/2022
1	ChromatinIBA 12/2022
1	Phenol (Carbolic Acid)FDA Link 11/2022
1	Satellite RNA (Satellite RNAs)IBA 11/2022
1	HeterochromatinIBA 11/2022
1	Histones (Histone)IBA 11/2022
1	S-Adenosylmethionine (Ademetionine)IBA 11/2022
1	PhenolsIBA 11/2022
1	Glutathione (Reduced Glutathione)IBA 10/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2022
1	Nitrofurantoin (Macrodantin)FDA LinkGeneric 10/2022
1	Bortezomib (Velcade)FDA Link 03/2022
1	Voltage-Gated Sodium ChannelsIBA 01/2022
1	TRPV1 receptorIBA 01/2022
1	Levodopa (L Dopa)FDA LinkGeneric 06/2021
1	Inosine Diphosphate (IDP)IBA 01/2021
1	Ceftizoxime (Cefizox)FDA Link 01/2021
1	Technetium (Technetium 99m)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2021
1	Amino Acids FDA Link 01/2021
1	NaphthoquinonesIBA 06/2020
1	lapacholIBA 06/2020
1	VaccinesIBA 01/2020
1	Chelating AgentsIBA 01/2020
1	Spider Venoms (Venom, Spider)IBA 03/2019
1	DNA (Deoxyribonucleic Acid)IBA 03/2019
1	Antimicrobial PeptidesIBA 03/2019
1	Peptide Hydrolases (Proteases)FDA Link 10/2018
1	CanagliflozinIBA 01/2018
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2018

Therapy/Procedure

2	Therapeutics 07/2005 - 07/2002
1	Radiotherapy 01/2018