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Soo Ok Lee Selected Research

Prostatic Neoplasms (Prostate Cancer)

11/2020Corrigendum to 'New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells'.
11/2020Correction: Differential androgen deprivation therapies with anti-androgens Casodex/bicalutamide or MDV3100/enzalutamide versus anti-androgen receptor ASC-J9® lead to promotion versus suppression of prostate cancer metastasis.
1/2020Glucocorticoid receptor upregulation increases radioresistance and triggers androgen independence of prostate cancer.
6/2019IL-6 signaling contributes to radioresistance of prostate cancer through key DNA repair-associated molecules ATM, ATR, and BRCA 1/2.
1/2019Radiation-induced glucocorticoid receptor promotes CD44+ prostate cancer stem cell growth through activation of SGK1-Wnt/β-catenin signaling.
1/2019Glucocorticoid receptor upregulation increases radioresistance and triggers androgen independence of prostate cancer.
1/2018Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels.
1/2018Adipocytes affect castration-resistant prostate cancer cells to develop the resistance to cytotoxic action of NK cells with alterations of PD-L1/NKG2D ligand levels in tumor cells.
12/2016Targeting fatty acid synthase with ASC-J9 suppresses proliferation and invasion of prostate cancer cells.
9/2015Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2α/androgen receptor signals.
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Soo Ok Lee Research Topics

Disease

38Prostatic Neoplasms (Prostate Cancer)
11/2020 - 07/2002
29Neoplasms (Cancer)
01/2019 - 07/2002
12Lung Neoplasms (Lung Cancer)
01/2022 - 04/2005
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 01/2014
7Neoplasm Metastasis (Metastasis)
11/2020 - 03/2006
3Asthma (Bronchial Asthma)
02/2009 - 01/2006
2Hypoxia (Hypoxemia)
06/2016 - 09/2015
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2016 - 01/2013
2Atherosclerosis
01/2016 - 06/2014
2Abdominal Aortic Aneurysm
01/2016 - 10/2015
2Carcinogenesis
06/2014 - 11/2012
2Liver Neoplasms (Liver Cancer)
01/2014 - 04/2013
2Liver Cirrhosis (Hepatic Cirrhosis)
01/2014 - 04/2013
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
11/2008 - 01/2007
1Infections
02/2016
1Heart Failure
01/2016
1Cardiomegaly (Heart Hypertrophy)
01/2016
1Cardiovascular Diseases (Cardiovascular Disease)
01/2016
1Stroke (Strokes)
01/2016
1Hypertrophy
01/2016
1Hypertension (High Blood Pressure)
01/2016
1Hemophilia A (Haemophilia)
01/2016
1Obesity
01/2016
1Kidney Calculi (Kidney Stone)
08/2014
1Nephrolithiasis
08/2014
1Inflammation (Inflammations)
06/2014
1Necrosis
02/2014
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2014
1X-Linked Bulbo-Spinal Atrophy
01/2014
1Insulin Resistance
01/2013
1Androgen-Insensitivity Syndrome (Testicular Feminization)
01/2013
1Lymphoma (Lymphomas)
05/2007
1Renal Cell Carcinoma (Grawitz Tumor)
05/2007
1Ovarian Neoplasms (Ovarian Cancer)
05/2007
1Melanoma (Melanoma, Malignant)
05/2007

Drug/Important Bio-Agent (IBA)

27Androgen Receptors (Androgen Receptor)IBA
11/2020 - 07/2002
25AndrogensIBA
11/2020 - 07/2002
13Interleukin-6 (Interleukin 6)IBA
01/2022 - 01/2003
9Prostate-Specific Antigen (Semenogelase)IBA
07/2013 - 07/2002
8Cisplatin (Platino)FDA LinkGeneric
01/2021 - 09/2015
7LigandsIBA
07/2018 - 04/2005
4Interleukin-4 (Interleukin 4)IBA
02/2009 - 09/2003
4SeleniumIBA
07/2006 - 01/2004
3Death Domain ReceptorsIBA
10/2020 - 01/2018
3Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
01/2020 - 01/2019
3Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
02/2015 - 06/2013
3Small Interfering RNA (siRNA)IBA
06/2014 - 09/2004
3NF-kappa B (NF-kB)IBA
01/2008 - 07/2005
3Hormones (Hormone)IBA
08/2005 - 09/2003
2LipidsIBA
01/2021 - 01/2016
2bicalutamide (Casodex)FDA LinkGeneric
11/2020 - 07/2013
2enzalutamideIBA
11/2020 - 07/2013
2Mifepristone (RU 486)FDA Link
01/2019 - 01/2019
2Conditioned Culture MediaIBA
07/2018 - 01/2018
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2017 - 10/2017
2CytokinesIBA
09/2015 - 09/2004
2CarcinogensIBA
06/2014 - 04/2005
2Estrogens (Estrogen)FDA Link
01/2014 - 04/2005
2Immunoglobulin E (IgE)IBA
02/2009 - 10/2006
1CateninsIBA
01/2019
1Myristic Acid (Tetradecanoic Acid)IBA
07/2018
1phorbolIBA
07/2018
1Janus Kinase InhibitorsIBA
01/2018
1Fatty Acids (Saturated Fatty Acids)IBA
12/2016
1EnzymesIBA
12/2016
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
12/2016
1CeruleninIBA
08/2016
1LeptinIBA
01/2016
1Blood Coagulation Factors (Coagulation Factor)IBA
01/2016
1Insulin (Novolin)FDA Link
01/2016
1Biomarkers (Surrogate Marker)IBA
02/2015
1LuciferasesIBA
02/2015
1OxalatesIBA
08/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2014
1LectinsIBA
06/2014
1Oxidized LDL ReceptorsIBA
06/2014
1LDL Receptors (LDL Receptor)IBA
06/2014
1IntegrinsIBA
06/2014
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2014
1Therapeutic UsesIBA
01/2014
1Phosphotransferases (Kinase)IBA
01/2014
1cryptotanshinoneIBA
07/2013
1InterleukinsIBA
06/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
06/2013
1Thioacetamide (Thioacetamid)IBA
04/2013
1TocotrienolsIBA
02/2013
1Glucose (Dextrose)FDA LinkGeneric
01/2013
1DecitabineFDA Link
11/2012
1Phenobarbital (Luminal)FDA Link
05/2012
1Interferon Regulatory FactorsIBA
11/2008
1Charcoal (Charbon)IBA
09/2007
1Growth InhibitorsIBA
05/2007

Therapy/Procedure

15Therapeutics
11/2020 - 07/2002
11Castration
01/2019 - 02/2009
4Radiotherapy
06/2019 - 11/2015
2Transplantation
01/2014 - 04/2013
1Immunotherapy
03/2018
1Drug Therapy (Chemotherapy)
09/2015
1Cell Transplantation
09/2014
1Liver Transplantation
04/2013