Chiara Lanzillotta Selected Research

Down Syndrome (Down's Syndrome)

1/2019	Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome.
1/2018	Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome.
1/2016	Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome.

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Chiara Lanzillotta Research Topics

Disease

10	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 01/2016
6	Insulin Resistance 04/2023 - 10/2018
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2016
5	Cognitive Dysfunction 11/2021 - 01/2017
3	Mitochondrial Diseases (Mitochondrial Disease) 11/2021 - 12/2018
3	Down Syndrome (Down's Syndrome) 01/2019 - 01/2016
2	Neoplasms (Cancer) 11/2020 - 01/2020
1	Intellectual Disability (Idiocy) 01/2023
1	Rett Syndrome (Rett's Disorder) 01/2023
1	Proteostasis Deficiencies 01/2022
1	Atrophy 01/2021
1	Tauopathies 01/2021
1	Trisomy (Trisomies) 01/2021
1	Neoplasm Metastasis (Metastasis) 11/2020
1	Starvation 11/2020
1	Adenocarcinoma of Lung 11/2020
1	Skin Neoplasms (Skin Cancer) 01/2020
1	Genomic Instability 01/2020
1	Carcinogenesis 01/2020
1	Obesity 01/2019
1	Fatty Liver 01/2019
1	Dementia (Dementias) 12/2018
1	Disease Progression 10/2018

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 04/2023 - 01/2016
6	Insulin (Novolin)FDA Link 04/2023 - 01/2018
5	Glucose (Dextrose)FDA LinkGeneric 04/2023 - 10/2018
3	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2016
3	HexosaminesIBA 04/2021 - 10/2018
3	biliverdin reductaseIBA 01/2020 - 01/2019
2	AntioxidantsIBA 03/2024 - 11/2021
2	Protein AggregatesIBA 01/2022 - 11/2021
2	Phosphotransferases (Kinase)IBA 01/2021 - 11/2020
2	ProteomeIBA 01/2021 - 01/2020
2	Insulin ReceptorIBA 01/2020 - 01/2019
2	Sirolimus (Rapamycin)FDA Link 01/2019 - 01/2018
1	EnzymesIBA 03/2024
1	Metformin (Glucophage)FDA LinkGeneric 01/2023
1	ManganeseIBA 01/2021
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2020
1	Serine (L-Serine)FDA Link 11/2020
1	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA 11/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020
1	Amino Acids FDA Link 11/2020
1	Adenylate KinaseIBA 11/2020
1	Adenosine Triphosphate (ATP)IBA 11/2020
1	Adenosine Monophosphate (AMP)IBA 11/2020
1	Biomarkers (Surrogate Marker)IBA 12/2018
1	tau Proteins (tau Protein)IBA 12/2018
1	Free RadicalsIBA 01/2016
1	TOR Serine-Threonine KinasesIBA 01/2016

Therapy/Procedure

2	Therapeutics 01/2023 - 01/2017