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Jörn Lötsch Selected Research

Miosis

5/2010A KCNJ6 (Kir3.2, GIRK2) gene polymorphism modulates opioid effects on analgesia and addiction but not on pupil size.
10/2003Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine.

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Jörn Lötsch Research Topics

Disease

70Pain (Aches)
01/2023 - 10/2002
12Hyperalgesia
04/2020 - 03/2003
9Neuralgia (Stump Neuralgia)
03/2022 - 12/2009
8Respiratory Insufficiency (Respiratory Failure)
12/2012 - 10/2003
7Neoplasms (Cancer)
01/2024 - 05/2009
6Inflammation (Inflammations)
11/2014 - 11/2006
6Chronic Pain
01/2013 - 11/2009
5Nausea
10/2013 - 01/2003
4Breast Neoplasms (Breast Cancer)
03/2022 - 05/2009
4Multiple Sclerosis
10/2018 - 12/2007
4Hepatitis C
07/2012 - 01/2010
4Infections
01/2012 - 05/2002
4Chronic Hepatitis C
08/2011 - 01/2010
3Alzheimer Disease (Alzheimer's Disease)
11/2014 - 11/2003
3Dopa-responsive Dystonia
09/2008 - 06/2007
2Fatigue
01/2024 - 12/2009
2Postoperative Pain
11/2019 - 01/2015
2Mental Disorders (Mental Disorder)
01/2019 - 06/2011
2Rheumatic Diseases (Rheumatism)
07/2014 - 11/2012
2Osteoarthritis
07/2014 - 12/2007
2Melanoma (Melanoma, Malignant)
01/2014 - 12/2012
2Cancer Pain
12/2012 - 01/2010
2Miosis
05/2010 - 10/2003
2Asthma (Bronchial Asthma)
05/2009 - 12/2007
2Body Weight (Weight, Body)
09/2005 - 12/2004
2Renal Insufficiency (Renal Failure)
05/2005 - 10/2002
1Fibromyalgia (Fibrositis)
01/2024
1COVID-19
01/2024
1Obesity
05/2022
1Diabetes Mellitus
10/2021
1Anosmia
10/2021
1Parkinson Disease (Parkinson's Disease)
10/2020

Drug/Important Bio-Agent (IBA)

26Analgesics (Analgesic Drugs)IBA
12/2020 - 01/2003
18Opioid Analgesics (Opioids)IBA
11/2019 - 03/2003
13Morphine (MS Contin)FDA LinkGeneric
12/2012 - 10/2002
11Capsaicin (Zostrix)FDA Link
04/2020 - 11/2008
10GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA
02/2013 - 11/2006
6LipidsIBA
10/2020 - 09/2007
6Opioid Receptors (Opioid Receptor)IBA
11/2019 - 05/2003
6mu Opioid Receptors (mu Opioid Receptor)IBA
12/2009 - 01/2003
5Antiviral Agents (Antivirals)IBA
01/2024 - 01/2010
5Ion Channels (Ion Channel)IBA
06/2020 - 01/2015
5MentholFDA Link
01/2019 - 12/2009
4Biomarkers (Surrogate Marker)IBA
01/2019 - 11/2003
4sapropterin (tetrahydrobiopterin)FDA Link
12/2012 - 11/2006
4Ribavirin (Virazole)FDA LinkGeneric
12/2011 - 03/2011
3Proteins (Proteins, Gene)FDA Link
03/2022 - 08/2009
3anandamide (arachidonylethanolamide)IBA
10/2020 - 11/2007
3Dronabinol (THC)FDA LinkGeneric
12/2019 - 11/2014
3Transient Receptor Potential ChannelsIBA
01/2015 - 02/2008
3EndocannabinoidsIBA
11/2014 - 11/2007
3Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2009 - 11/2006
2AsparagineIBA
05/2022 - 03/2009
2Amino AcidsFDA Link
05/2022 - 03/2009
2ChemokinesIBA
03/2022 - 02/2013
2Pregabalin (Lyrica)FDA Link
04/2020 - 12/2009
2cinnamaldehyde (cinnamic aldehyde)FDA Link
01/2019 - 12/2018
2LeukotrienesIBA
01/2017 - 05/2009
2MicroRNAs (MicroRNA)IBA
11/2015 - 07/2011
2RNA (Ribonucleic Acid)IBA
11/2015 - 09/2007
2Fatty Acids (Saturated Fatty Acids)IBA
01/2015 - 11/2007
2TransferasesIBA
01/2015 - 08/2003
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
11/2014 - 12/2007
2Genetic Markers (Genetic Marker)IBA
10/2013 - 12/2011
2Fentanyl (Sublimaze)FDA LinkGeneric
01/2013 - 01/2009
2A-factor (Streptomyces)IBA
10/2012 - 08/2003
2InterferonsIBA
08/2011 - 05/2011
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
06/2011 - 12/2007
2Methadone (Dolophine)FDA LinkGeneric
05/2010 - 06/2009
2Guanosine Triphosphate (GTP)IBA
11/2009 - 02/2008
2Type 1 Melanocortin ReceptorIBA
08/2009 - 02/2008
2Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
08/2009 - 02/2008
2EnzymesIBA
09/2008 - 11/2006
2Alfentanil (Alfenta)FDA LinkGeneric
09/2006 - 02/2005
2morphine-6-glucuronideIBA
05/2005 - 01/2003
2GlucuronidesIBA
08/2003 - 01/2003
1Tyrosine (L-Tyrosine)FDA Link
01/2024
1Glutamine (L-Glutamine)FDA Link
01/2024
1Glucose (Dextrose)FDA LinkGeneric
01/2024
1pyrimidineIBA
01/2024
1purineIBA
01/2024
1AcidsIBA
01/2024
1Glutathione (Reduced Glutathione)IBA
05/2022
1propionylcarnitineIBA
05/2022
1Methionine (L-Methionine)FDA Link
05/2022
1DeoxycytidineIBA
05/2022
1Glucuronic Acid (Glucuronate)IBA
05/2022
1Cysteine (L-Cysteine)FDA Link
05/2022
1Adenosine Monophosphate (AMP)IBA
05/2022
1NAD (NADH)IBA
05/2022
1Sirtuin 2IBA
03/2022
1Indicators and Reagents (Reagents)IBA
10/2021
1Glucosylceramides (Glucocerebrosides)IBA
10/2020
1lysophosphatidic acidIBA
10/2020
1Glucosylceramidase (Glucocerebrosidase)IBA
10/2020

Therapy/Procedure

30Therapeutics
11/2022 - 02/2005
11Analgesia
11/2014 - 05/2003
2Pain Management
01/2021 - 08/2009
1Precision Medicine
01/2023
1Intradermal Injections
04/2020