Ryoko Kuromatsu Selected Research

Therapeutic Uses

1/2022	Evaluating the therapeutic effect of lenvatinib against advanced hepatocellular carcinoma by measuring blood flow changes using contrast-enhanced ultrasound.
8/2020	Primary Treatment with Molecular-Targeted Agents for Hepatocellular Carcinoma: A Propensity Score-matching Analysis.
12/2015	Sorafenib for the treatment of advanced hepatocellular carcinoma with extrahepatic metastasis: a prospective multicenter cohort study.
6/2012	Serum vascular endothelial growth factor as a predictor of response and survival in patients with advanced hepatocellular carcinoma undergoing hepatic arterial infusion chemotherapy.

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Ryoko Kuromatsu Research Topics

Disease

53	Hepatocellular Carcinoma (Hepatoma) 09/2023 - 08/2002
22	Neoplasms (Cancer) 01/2023 - 08/2002
6	Fibrosis (Cirrhosis) 01/2021 - 09/2010
5	Infections 01/2019 - 04/2007
4	Neoplasm Metastasis (Metastasis) 01/2022 - 09/2014
4	Thrombocytopenia (Thrombopenia) 11/2021 - 01/2009
3	Liver Neoplasms (Liver Cancer) 02/2023 - 01/2019
3	Fatigue 09/2022 - 04/2020
3	Liver Diseases (Liver Disease) 04/2022 - 01/2009
3	Chronic Hepatitis C 02/2018 - 09/2010
3	Liver Cirrhosis (Hepatic Cirrhosis) 11/2014 - 01/2011
2	Necrosis 01/2019 - 02/2003
2	Thrombosis (Thrombus) 02/2016 - 08/2002
2	Insulin Resistance 01/2015 - 09/2010
1	Fatty Liver 02/2023
1	Hypoxia (Hypoxemia) 01/2023
1	Hyperemia 04/2022
1	Varicose Veins (Varicose Vein) 01/2022
1	Alopecia (Baldness) 11/2021
1	Disease Progression 01/2021
1	Chronic Hepatitis B 01/2021
1	Hypertension (High Blood Pressure) 07/2020
1	Atrophy 03/2017
1	Non-alcoholic Fatty Liver Disease 06/2016
1	Overweight 01/2015
1	Diabetes Mellitus 01/2015
1	Hemorrhage 06/2014
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 06/2014
1	Rupture 01/2014
1	Diarrhea 01/2013
1	Type 2 Diabetes Mellitus (MODY) 09/2010
1	Hepatitis C 09/2010
1	Glucose Intolerance 09/2007

Drug/Important Bio-Agent (IBA)

11	Sorafenib (BAY 43-9006)FDA Link 11/2021 - 01/2013
10	lenvatinibIBA 09/2023 - 01/2020
6	AlbuminsIBA 02/2023 - 09/2014
6	BilirubinIBA 02/2023 - 09/2014
5	Bevacizumab (Avastin)FDA Link 02/2023 - 06/2021
5	atezolizumabIBA 02/2023 - 06/2021
4	Antiviral Agents (Antivirals)IBA 05/2022 - 01/2009
4	Therapeutic UsesIBA 01/2022 - 06/2012
3	Cisplatin (Platino)FDA LinkGeneric 10/2021 - 02/2016
3	NivolumabIBA 01/2021 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 07/2020 - 01/2011
3	AdiponectinIBA 01/2015 - 09/2010
2	Prothrombin (Factor II)IBA 01/2022 - 09/2014
2	Fetal Proteins (Fetoprotein)IBA 07/2020 - 06/2016
2	asunaprevirIBA 02/2018 - 01/2016
2	daclatasvirIBA 02/2018 - 01/2016
2	Ethiodized Oil (Ethiodol)FDA Link 12/2017 - 02/2016
2	SuspensionsIBA 12/2017 - 02/2016
2	Fluorouracil (Carac)FDA LinkGeneric 12/2017 - 02/2016
2	acarboxyprothrombin (PIVKA)IBA 06/2016 - 06/2003
2	AdipokinesIBA 01/2015 - 09/2010
2	Insulin (Novolin)FDA Link 01/2015 - 09/2010
2	Serum AlbuminIBA 11/2014 - 08/2014
1	RamucirumabIBA 02/2023
1	Insulin-Like PeptidesIBA 01/2023
1	Insulin-Like Growth Factor Binding Protein 1IBA 01/2023
1	Tyrosine Kinase InhibitorsIBA 01/2023
1	EnzymesIBA 11/2021
1	Tenofovir (Viread)FDA Link 01/2021
1	tenofovir alafenamideIBA 01/2021
1	adefovir dipivoxil (Hepsera)FDA Link 01/2021
1	Adenosine Monophosphate (AMP)IBA 01/2021
1	miriplatinIBA 01/2019
1	Epirubicin (Ellence)FDA LinkGeneric 01/2019
1	Branched-Chain Amino AcidsIBA 03/2017
1	gadolinium ethoxybenzyl DTPA FDA Link 08/2016
1	Pioglitazone (Actos)FDA Link 01/2015
1	DNA (Deoxyribonucleic Acid)IBA 11/2014
1	eltrombopag FDA Link 06/2014
1	Thrombopoietin (c-mpl Ligand)IBA 06/2014
1	Peptides (Polypeptides)IBA 09/2013
1	AntigensIBA 09/2013
1	EpitopesIBA 09/2013
1	Cancer VaccinesIBA 09/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2012
1	Alanine Transaminase (SGPT)IBA 05/2012
1	Vitamin K 2 (Vitamin K2)IBA 08/2011
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2011
1	LeptinIBA 09/2010
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 09/2010
1	InterferonsIBA 09/2010
1	pigment epithelium-derived factorIBA 01/2010
1	Thrombopoietin ReceptorsIBA 01/2009
1	Glucose (Dextrose)FDA LinkGeneric 09/2007

Therapy/Procedure

20	Therapeutics 09/2023 - 01/2009
9	Drug Therapy (Chemotherapy) 04/2022 - 08/2002
4	Radiofrequency Ablation 08/2019 - 02/2003
3	Radiotherapy 04/2022 - 01/2019
2	Hepatectomy 07/2020 - 08/2016
2	Platelet Transfusion (Blood Platelet Transfusions) 06/2014 - 01/2009
2	Liver Transplantation 01/2014 - 01/2013
2	Splenectomy 01/2013 - 01/2009
1	Duration of Therapy 07/2023
1	Fontan Procedure (Fontan Operation) 04/2022
1	Combination Drug Therapy (Combination Chemotherapy) 11/2021
1	Drug Tapering 04/2020
1	Intra-Arterial Infusions 12/2017