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Hirohisa Kurachi Selected Research

taxane

1/2016Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel.
1/2011Phase II clinical study of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of recurrent ovarian cancer (Tohoku Gynecologic Cancer Unit 101 Group Study).

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Hirohisa Kurachi Research Topics

Disease

31Neoplasms (Cancer)
09/2017 - 01/2004
20Ovarian Neoplasms (Ovarian Cancer)
09/2017 - 04/2004
7Ascites
01/2015 - 05/2004
5Carcinoma (Carcinomatosis)
05/2015 - 10/2004
5Adenocarcinoma
07/2013 - 10/2003
3Hypoxia (Hypoxemia)
05/2015 - 06/2008
3Mucinous Adenocarcinoma (Mucinous Carcinoma)
03/2014 - 10/2003
3Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
01/2014 - 01/2010
3Breast Neoplasms (Breast Cancer)
11/2005 - 10/2003
2Chorioamnionitis
03/2016 - 11/2013
2Inflammation (Inflammations)
03/2016 - 11/2013
2Uterine Cervical Neoplasms (Cancer of the Cervix)
07/2014 - 07/2013
2Endometrioid Carcinoma
03/2014 - 10/2003
2Dyslipidemias (Dyslipidemia)
01/2014 - 01/2010
2Insulin Resistance
09/2013 - 11/2011
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2013 - 06/2008
2Neonatal Hyperbilirubinemia
04/2005 - 08/2003
2Hyperbilirubinemia
04/2005 - 08/2003
2Choriocarcinoma
12/2003 - 01/2002
1Infections
03/2016
1Hemorrhage
01/2015
1Disease Progression
12/2014
1Carcinosarcoma
12/2014
1Sarcoma (Soft Tissue Sarcoma)
12/2014
1Wilms Tumor (Wilm's Tumor)
10/2014
1Neoplasm Metastasis (Metastasis)
05/2014
1Ovarian Epithelial Carcinoma
03/2014
1Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2014
1Diabetes Mellitus
01/2014
1Glucose Intolerance
01/2014
1Anovulation
09/2013

Drug/Important Bio-Agent (IBA)

9Cisplatin (Platino)FDA LinkGeneric
09/2017 - 04/2004
7PlatinumIBA
09/2017 - 03/2005
6Estrogens (Estrogen)FDA Link
11/2013 - 10/2003
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2015 - 05/2007
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
04/2006 - 04/2004
3Estradiol (Delestrogen)FDA LinkGeneric
09/2017 - 07/2013
3Interleukin-6 (Interleukin 6)IBA
03/2016 - 11/2013
3Paclitaxel (Taxol)FDA LinkGeneric
01/2016 - 11/2004
3Clomiphene (Clomifene)FDA LinkGeneric
01/2014 - 01/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2013 - 11/2011
3fasudil (AT 877)IBA
01/2012 - 05/2007
3Telomerase (Telomerase Reverse Transcriptase)IBA
12/2004 - 10/2003
2Phosphotransferases (Kinase)IBA
03/2016 - 01/2012
2CytokinesIBA
03/2016 - 11/2013
2taxaneIBA
01/2016 - 01/2011
2MicroRNAs (MicroRNA)IBA
05/2015 - 05/2013
2Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2015 - 11/2013
2Messenger RNA (mRNA)IBA
05/2014 - 06/2008
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
09/2013 - 01/2010
2Proteins (Proteins, Gene)FDA Link
01/2012 - 01/2012
2BezafibrateIBA
11/2011 - 01/2010
2Irinotecan (Camptosar)FDA LinkGeneric
01/2011 - 07/2007
2NF-kappa B (NF-kB)IBA
11/2005 - 11/2004
2MucinsIBA
06/2005 - 10/2003
2BilirubinIBA
04/2005 - 08/2003
2Uridine Diphosphate (UDP)IBA
04/2005 - 08/2003
2Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
04/2005 - 08/2003
2EnzymesIBA
04/2005 - 08/2003
2Raloxifene Hydrochloride (Evista)FDA Link
12/2004 - 10/2003
2BAY 11-7085IBA
11/2004 - 05/2004
1Estrogen ReceptorsIBA
09/2017
1Small Interfering RNA (siRNA)IBA
09/2017
1Apoptosis Regulatory ProteinsIBA
09/2017
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
01/2017
1Histones (Histone)IBA
12/2015
1Lysine (L-Lysine)FDA Link
12/2015
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
05/2015
1N- (3,5- bis(trifluoromethyl)phenyl)- 5- chloro- 2- hydroxybenzamideIBA
04/2015
1tocilizumab (atlizumab)FDA Link
01/2015
1ResveratrolIBA
01/2015
1Carboplatin (JM8)FDA LinkGeneric
12/2014
1Transcription Factors (Transcription Factor)IBA
10/2014
1Bevacizumab (Avastin)FDA Link
10/2014
1ZincIBA
10/2014
1JNK Mitogen-Activated Protein KinasesIBA
09/2014
1Neutralizing AntibodiesIBA
07/2014
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
07/2014
1Taxoids (Taxanes)IBA
03/2014
1Fatty Acids (Saturated Fatty Acids)IBA
02/2014
1Insulin (Novolin)FDA Link
01/2014
1Blood Glucose (Blood Sugar)IBA
01/2014
1Glucose (Dextrose)FDA LinkGeneric
01/2014
1Testosterone (Sustanon)FDA Link
01/2014
1LuteinIBA
11/2013
1Aromatase (CYP19)IBA
11/2013
12,4-thiazolidinedione (thiazolidinedione)IBA
09/2013
1Pioglitazone (Actos)FDA Link
09/2013
1Follicle Stimulating Hormone (Follitropin)FDA Link
09/2013

Therapy/Procedure

9Therapeutics
04/2015 - 02/2009
5Drug Therapy (Chemotherapy)
01/2016 - 02/2009
5Hysterectomy
11/2015 - 06/2005
3Radiotherapy
07/2014 - 06/2008
2Combination Drug Therapy (Combination Chemotherapy)
01/2011 - 07/2007
2Laparotomy
01/2008 - 01/2007
1Cesarean Section (Caesarean Section)
01/2015
1Molecular Targeted Therapy
01/2015
1Platelet Transfusion (Blood Platelet Transfusions)
01/2015
1Salpingo-oophorectomy
12/2014
1Splenectomy
07/2014