Upa Kukongviriyapan Selected Research

Nitric Oxide (Nitrogen Monoxide)

1/2020	Virgin rice bran oil alleviates hypertension through the upregulation of eNOS and reduction of oxidative stress and inflammation in L-NAME-induced hypertensive rats.
10/2018	Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-β1 and MMPs Protein Expression.
7/2017	Garcinia mangostana pericarp extract protects against oxidative stress and cardiovascular remodeling via suppression of p47phox and iNOS in nitric oxide deficient rats.
12/2016	Tetrahydrocurcumin in combination with deferiprone attenuates hypertension, vascular dysfunction, baroreflex dysfunction, and oxidative stress in iron-overloaded mice.
2/2016	Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in L-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT₁R Expression.
2/2016	Protocatechuic Acid Restores Vascular Responses in Rats With Chronic Diabetes Induced by Streptozotocin.
7/2015	Mamao Pomace Extract Alleviates Hypertension and Oxidative Stress in Nitric Oxide Deficient Rats.
11/2014	Curcumin improves endothelial dysfunction and vascular remodeling in 2K-1C hypertensive rats by raising nitric oxide availability and reducing oxidative stress.
4/2012	Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency.
5/2011	Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension.

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Upa Kukongviriyapan Research Topics

Disease

25	Hypertension (High Blood Pressure) 01/2021 - 08/2009
10	Inflammation (Inflammations) 01/2022 - 04/2009
10	Neoplasms (Cancer) 01/2020 - 04/2009
9	Cholangiocarcinoma 01/2020 - 04/2009
7	Vascular Remodeling 10/2018 - 01/2014
6	Thalassemia 07/2019 - 01/2007
6	Insulin Resistance 03/2018 - 01/2014
5	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 06/2017
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2018 - 01/2014
4	Fibrosis (Cirrhosis) 01/2022 - 11/2015
4	Iron Overload 07/2019 - 01/2008
4	beta-Thalassemia (Cooley's Anemia) 10/2012 - 01/2007
3	Genetic Risk Score 01/2021 - 01/2019
3	Renovascular Hypertension (Goldblatt Syndrome) 03/2018 - 07/2015
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 03/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2018
2	Hypertrophy 01/2021 - 11/2015
2	Coronary Stenosis (Coronary Artery Stenosis) 11/2018 - 01/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2018 - 11/2013
2	Carcinogenesis 06/2014 - 04/2009
2	Body Weight (Weight, Body) 01/2014 - 04/2012
2	Bile Duct Neoplasms (Bile Duct Cancer) 01/2012 - 08/2010
1	Left Ventricular Dysfunction 02/2020
1	Ventricular Dysfunction 02/2020
1	Dyslipidemias (Dyslipidemia) 01/2019
1	Hypertriglyceridemia 01/2019
1	Necrosis 10/2018
1	Atherosclerosis 01/2018

Drug/Important Bio-Agent (IBA)

14	AntioxidantsIBA 01/2020 - 04/2009
13	NG-Nitroarginine Methyl Ester (L-NAME)IBA 03/2020 - 05/2011
11	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 01/2007
8	Antihypertensive Agents (Antihypertensives)IBA 03/2020 - 01/2014
7	Proteins (Proteins, Gene)FDA Link 03/2018 - 01/2007
6	CurcuminIBA 01/2021 - 08/2010
6	arginine methyl esterIBA 02/2020 - 05/2011
6	Glutathione (Reduced Glutathione)IBA 07/2019 - 01/2007
5	Captopril (Capoten)FDA LinkGeneric 04/2019 - 02/2016
5	Protein Hydrolysates FDA Link 03/2018 - 02/2015
5	CarbohydratesIBA 02/2018 - 01/2014
5	tetrahydrocurcuminIBA 12/2016 - 05/2011
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 04/2009
4	CadmiumIBA 01/2021 - 02/2011
4	Drinking WaterIBA 03/2020 - 04/2012
4	LipidsIBA 01/2019 - 01/2014
4	EnzymesIBA 05/2018 - 04/2009
4	asiatic acidIBA 10/2017 - 01/2014
4	Acetylcholine (Acetylcholine Chloride)FDA Link 02/2016 - 09/2010
4	Hemoglobin EIBA 11/2014 - 01/2008
3	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 10/2017
3	ORALIT (ORS)IBA 01/2021 - 01/2019
3	Insulin (Novolin)FDA Link 01/2019 - 01/2015
3	Oxidants (Oxidizing Agents)IBA 05/2018 - 01/2008
3	Glucose (Dextrose)FDA LinkGeneric 03/2018 - 01/2015
3	phenethyl isothiocyanate (PEITC)IBA 01/2018 - 11/2013
3	IronIBA 12/2016 - 01/2007
3	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 02/2016 - 09/2010
3	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 02/2016 - 09/2010
2	AlbuminsIBA 01/2021 - 03/2018
2	MetalsIBA 01/2021 - 09/2010
2	CreatinineIBA 01/2021 - 03/2018
2	FlavonoidsIBA 02/2020 - 01/2018
2	tangeretinIBA 02/2020 - 01/2020
2	HesperidinIBA 10/2018 - 01/2018
2	CollagenIBA 10/2018 - 11/2015
2	Transcription Factors (Transcription Factor)IBA 05/2018 - 08/2016
2	DisintegrinsIBA 01/2018 - 06/2017
2	Metalloproteases (Metalloproteinases)IBA 01/2018 - 06/2017
2	ThrombospondinsIBA 01/2018 - 06/2017
2	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2017 - 06/2015
2	Malondialdehyde (Propanedial)IBA 02/2016 - 11/2014
2	Superoxides (Superoxide)IBA 02/2016 - 11/2013
2	CytokinesIBA 08/2015 - 04/2009
2	QuercetinIBA 06/2014 - 10/2012
2	Vasodilator Agents (Vasodilators)IBA 01/2014 - 10/2012
2	NAD (NADH)IBA 05/2010 - 04/2009
2	quinone (benzoquinone)IBA 05/2010 - 04/2009
1	vactosertibIBA 01/2022
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2021
1	NADP (NADPH)IBA 01/2021
1	Rice Bran OilIBA 01/2020
1	Phenformin (Fenformin)IBA 01/2020
1	Sildenafil Citrate (Viagra)FDA Link 01/2020
1	Lisinopril (Prinivil)FDA LinkGeneric 01/2020
1	Glutamate-Cysteine LigaseIBA 07/2019
1	Nuclear Proteins (Protein, Nuclear)IBA 07/2019
1	Oligonucleotide ProbesIBA 07/2019
1	nobiletinIBA 04/2019
1	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2019
1	HDL CholesterolIBA 01/2019
1	Superoxide DismutaseIBA 01/2019
1	Plasminogen Activator Inhibitor 1IBA 11/2018
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2018
1	Tumor Biomarkers (Tumor Markers)IBA 10/2018
1	Biomarkers (Surrogate Marker)IBA 03/2018
1	TransferasesIBA 01/2018
1	von Willebrand FactorIBA 01/2018

Therapy/Procedure

2	Chemoprevention 01/2020 - 08/2010
2	Drug Therapy (Chemotherapy) 05/2018 - 01/2012
2	Surgical Instruments (Clip) 03/2018 - 07/2015
2	Blood Transfusion (Blood Transfusions) 01/2008 - 01/2007