Geoffrey Krystal Selected Research

MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)

1/2002

Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.

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Geoffrey Krystal Research Topics

Disease

6	Leukemia 09/2003 - 01/2002
2	Myeloid Leukemia (Leukemia, Myelocytic) 05/2003 - 01/2002
1	Colorectal Neoplasms (Colorectal Cancer) 06/2015
1	Ataxia Telangiectasia (Louis Bar Syndrome) 04/2003
1	Neoplasms (Cancer) 02/2002
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2002

Drug/Important Bio-Agent (IBA)

6	Phosphotransferases (Kinase)IBA 09/2003 - 01/2002
3	Imatinib Mesylate (Gleevec)FDA Link 05/2003 - 01/2002
3	Proteins (Proteins, Gene)FDA Link 04/2003 - 01/2002
2	Histone Deacetylase InhibitorsIBA 09/2003 - 05/2003
2	Cytochromes c (Cytochrome c)IBA 09/2003 - 01/2002
2	CaspasesIBA 09/2003 - 09/2002
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 04/2003 - 09/2002
2	MitogensIBA 04/2003 - 01/2002
2	alvocidib (flavopiridol)IBA 04/2003 - 09/2002
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 04/2003 - 01/2002
1	Terpenes (Terpenoids)IBA 06/2015
1	Mevalonic Acid (Mevalonate)IBA 06/2015
1	Somatomedin Receptors (Somatomedin Receptor)IBA 06/2015
1	TOR Serine-Threonine KinasesIBA 06/2015
1	Protein Kinase CIBA 09/2003
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2003
1	Butyric Acid (Butanoic Acid)IBA 09/2003
1	bisindolylmaleimideIBA 09/2003
1	tanespimycin (17AAG)IBA 09/2003
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2003
1	7-hydroxystaurosporine (UCN 01)IBA 09/2003
1	Protein Kinases (Protein Kinase)IBA 04/2003
1	N- (2- (4- bromocinnamylamino)ethyl)- 5- isoquinolinesulfonamide (h89)IBA 04/2003
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 04/2003
1	4- (4- fluorophenyl)- 2- (4- hydroxyphenyl)- 5- (4- pyridyl)imidazoleIBA 04/2003
1	U 0126 (UO 126)IBA 04/2003
1	N(2)- (2- aminocyclohexyl)- N(6)- (3- chlorophenyl)- 9- ethyl- 9H- purine- 2,6- diamineIBA 04/2003
1	WortmanninIBA 04/2003
1	RoscovitineIBA 04/2003
1	Caffeine (No Doz)FDA LinkGeneric 04/2003
1	Sirolimus (Rapamycin)FDA Link 04/2003
1	p38 Mitogen-Activated Protein KinasesIBA 04/2003
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2003
1	Cell Cycle ProteinsIBA 09/2002
1	Transcription Factors (Transcription Factor)IBA 02/2002
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 02/2002
1	tyrosine receptor (receptor, tyrosine)IBA 02/2002
1	GTP Phosphohydrolases (GTPases)IBA 02/2002
1	2- (2- chloro- 4- iodophenylamino)- N- cyclopropylmethoxy- 3,4- difluorobenzamideIBA 01/2002
1	Mitogen-Activated Protein KinasesIBA 01/2002
1	Caspase 3 (Caspase-3)IBA 01/2002
1	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 01/2002
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2002

Therapy/Procedure

1	Therapeutics 06/2015