Michael Kramer Selected Research

Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

7/2023	Intensified cytarabine dose during consolidation in adult AML patients under 65 years is not associated with survival benefit: real-world data from the German SAL-AML registry.
1/2023	Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning.
1/2023	Allogeneic Hematopoietic Cell Transplantation vs Standard Consolidation Chemotherapy in Patients With Intermediate-Risk Acute Myeloid Leukemia: A Randomized Clinical Trial.
1/2023	Midostaurin in addition to intensive chemotherapy in acute myeloid leukemia with t(8;21) and KIT and/or FLT3- ITD mutations: results of the SAL MIDOKIT trial.
11/2022	Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia.
1/2022	Characteristics and outcome of patients with core-binding factor acute myeloid leukemia and FLT3-ITD: results from an international collaborative study.
1/2022	Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.
1/2021	Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia.
1/2021	Decitabine treatment in 311 patients with acute myeloid leukemia: outcome and impact of TP53 mutations - a registry based analysis.
9/2020	Multidrug-related protein 1 (MRP1) polymorphisms rs129081, rs212090, and rs212091 predict survival in normal karyotype acute myeloid leukemia.

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Michael Kramer Research Topics

Disease

24	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2023 - 07/2011
7	Neoplasms (Cancer) 02/2023 - 10/2012
6	Pain (Aches) 12/2015 - 01/2009
4	Leukemia 07/2023 - 04/2015
3	Chronic Kidney Failure (Chronic Renal Failure) 11/2023 - 01/2014
3	Obesity 10/2021 - 12/2010
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021 - 05/2018
2	Lupus Nephritis 11/2023 - 03/2016
2	Myasthenia Gravis 01/2023 - 01/2021
2	Pathologic Complete Response 01/2022 - 02/2012
2	Colonic Neoplasms (Colon Cancer) 01/2022 - 01/2019
2	Inflammation (Inflammations) 01/2022 - 10/2021
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 02/2016
2	Body Weight (Weight, Body) 01/2021 - 08/2013
2	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 01/2019
2	Infections 01/2020 - 12/2015
2	Prostatic Neoplasms (Prostate Cancer) 08/2017 - 01/2017
2	Hemorrhage 12/2015 - 10/2012
2	Pneumonia (Pneumonitis) 12/2015 - 02/2011
2	Thrombocytopenia (Thrombopenia) 05/2015 - 10/2012
2	Whiplash Injuries (Whiplash Injury) 08/2012 - 01/2009
2	Ileus 12/2010 - 12/2009
2	Acquired Immunodeficiency Syndrome (AIDS) 03/2010 - 11/2006
2	Wounds and Injuries (Trauma) 11/2006 - 07/2006
1	Sarcoma (Soft Tissue Sarcoma) 02/2023
1	Lymphocytosis 01/2023
1	Death (Near-Death Experience) 05/2022
1	Cytopenia 01/2022
1	cell-associated neurotoxicity 01/2022
1	Cytokine Release Syndrome 01/2022
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2022
1	Eczema 01/2022
1	Torsades de Pointes (Torsade de Pointes) 12/2021
1	Acute Pain 12/2021
1	Lung Neoplasms (Lung Cancer) 11/2021
1	Hypertension (High Blood Pressure) 10/2021
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 09/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Mesothelioma 01/2020
1	Clostridium Infections 01/2020

Drug/Important Bio-Agent (IBA)

6	Cytarabine (Cytosar-U)FDA LinkGeneric 07/2023 - 07/2011
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2021 - 10/2009
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2017
2	Cholinergic ReceptorsIBA 01/2023 - 01/2021
2	Core Binding Factors (Core-Binding Factor)IBA 01/2022 - 01/2017
2	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2017
2	Retinaldehyde (Retinal)IBA 10/2021 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 09/2020 - 08/2017
2	PlatinumIBA 01/2020 - 06/2009
2	Cisplatin (Platino)FDA LinkGeneric 12/2019 - 06/2009
2	Dexamethasone (Maxidex)FDA LinkGeneric 12/2019 - 08/2013
2	NucleophosminIBA 10/2019 - 03/2016
2	AntigensIBA 08/2017 - 01/2017
2	Sorafenib (BAY 43-9006)FDA Link 12/2015 - 06/2012
2	Antidepressive Agents (Antidepressants)IBA 05/2015 - 03/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2011 - 10/2010
2	Inosine Monophosphate (IMP)IBA 11/2009 - 10/2004
2	Fluorouracil (Carac)FDA LinkGeneric 06/2009 - 12/2008
2	VaccinesIBA 11/2006 - 05/2003
1	AntibodiesIBA 01/2023
1	midostaurinIBA 01/2023
1	Immune Checkpoint InhibitorsIBA 11/2022
1	RNA (Ribonucleic Acid)IBA 11/2022
1	Therapeutic UsesIBA 01/2022
1	CytokinesIBA 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	tocilizumab (atlizumab)FDA Link 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Circulating Tumor DNAIBA 01/2022
1	LigandsIBA 12/2021
1	Ion Channels (Ion Channel)IBA 12/2021
1	Sodium Channels (Sodium Channel)IBA 12/2021
1	((3- methoxythiophen- 2- yl)methyl)((2- (9- (pyridin- 2- yl)- 6- oxaspiro(4.5)decan- 9- yl)ethyl))amineIBA 12/2021
1	Opioid Receptors (Opioid Receptor)IBA 12/2021
1	Quinidine (Chinidin)FDA LinkGeneric 12/2021
1	Contraceptive Agents (Contraceptives)IBA 09/2021
1	plerixafor FDA Link 01/2021
1	AutoantibodiesIBA 01/2021
1	Decitabine FDA Link 01/2021
1	Tyrosine (L-Tyrosine)FDA Link 01/2021
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2021
1	multidrug resistance-associated protein 1IBA 09/2020
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2020
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2020

Therapy/Procedure

14	Therapeutics 02/2023 - 11/2006
8	Drug Therapy (Chemotherapy) 01/2023 - 02/2012
6	Cell Transplantation 01/2023 - 03/2016
4	Stem Cell Transplantation 01/2022 - 10/2012
3	Palliative Care (Palliative Therapy) 02/2023 - 11/2006
3	Hematopoietic Stem Cell Transplantation 01/2020 - 02/2016
3	Physical Therapy Modalities (Physical Therapy Technique) 08/2012 - 01/2009
2	Kidney Transplantation 11/2023 - 01/2014
2	Decompression 01/2017 - 07/2006
2	Gastric Balloon 12/2010 - 12/2009
1	Consolidation Chemotherapy 01/2023
1	Immunotherapy 11/2022
1	Patient Readmission 05/2022
1	Genomic Medicine 11/2021
1	Blood Component Removal (Apheresis) 01/2021
1	Radioimmunotherapy 01/2020