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Steffen Koschmieder Selected Research

bosutinib

10/2023Step-in dosing of bosutinib in pts with chronic phase chronic myeloid leukemia (CML) after second-generation tyrosine kinase inhibitor (TKI) therapy: results of the Bosutinib Dose Optimization (BODO) Study.
1/2018Bosutinib: A Potent Second-Generation Tyrosine Kinase Inhibitor.
1/2014Bosutinib: a novel second-generation tyrosine kinase inhibitor.
1/2013Profile of bosutinib and its clinical potential in the treatment of chronic myeloid leukemia.

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Steffen Koschmieder Research Topics

Disease

45Neoplasms (Cancer)
03/2024 - 03/2002
22BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2023 - 11/2003
20Primary Myelofibrosis (Myelosclerosis)
02/2024 - 01/2012
19Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2020 - 04/2002
17Leukemia
01/2023 - 04/2002
6Polycythemia Vera
03/2024 - 01/2018
5Splenomegaly
12/2023 - 01/2018
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2012 - 01/2009
4Essential Thrombocythemia
03/2024 - 01/2021
4Fibrosis (Cirrhosis)
12/2023 - 01/2020
4Disease Progression
01/2023 - 10/2018
4Systemic Mastocytosis
11/2022 - 01/2018
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 02/2007
4Thrombosis (Thrombus)
08/2021 - 05/2016
4Philadelphia Chromosome
01/2021 - 04/2006
4COVID-19
01/2021 - 01/2020
4Neoplasm Metastasis (Metastasis)
11/2020 - 01/2009
3Pruritus (Itching)
11/2022 - 01/2017
3Anemia
03/2022 - 01/2018
3Lung Neoplasms (Lung Cancer)
12/2011 - 03/2002
2Eosinophilia
11/2022 - 01/2020
2Thrombocytosis (Thrombocythemia)
04/2022 - 09/2021
2Thrombocytopenia (Thrombopenia)
06/2021 - 01/2020
2Hemorrhage
06/2021 - 02/2020
2Pneumonia (Pneumonitis)
01/2021 - 11/2020
2Infections
11/2020 - 06/2015
2Inflammation (Inflammations)
08/2019 - 05/2013
2Hematologic Diseases (Blood Diseases)
01/2018 - 02/2007
2Diarrhea
01/2018 - 01/2013
2Blast Crisis (Blast Phase)
09/2015 - 01/2013
2Chromosome Aberrations (Chromosome Abnormalities)
05/2013 - 09/2007
2Lymphoma (Lymphomas)
12/2011 - 03/2002
1Cytopenia
02/2024
1Malaria
12/2022
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
11/2022
1Leukocytosis (Pleocytosis)
04/2022
1von Willebrand Diseases (von Willebrand's Disease)
09/2021
1Hypertension (High Blood Pressure)
08/2021
1Renal Insufficiency (Renal Failure)
06/2021
1Liver Diseases (Liver Disease)
06/2021
1Thrombophilia
06/2021

Drug/Important Bio-Agent (IBA)

12ruxolitinibIBA
12/2023 - 01/2012
12Tyrosine Kinase InhibitorsIBA
10/2023 - 05/2013
11Proteins (Proteins, Gene)FDA Link
11/2022 - 01/2005
8Phosphotransferases (Kinase)IBA
11/2020 - 04/2006
7CalreticulinIBA
01/2024 - 01/2016
7Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2020 - 07/2009
6Janus Kinase InhibitorsIBA
12/2023 - 01/2018
5CytokinesIBA
01/2023 - 04/2002
5Biomarkers (Surrogate Marker)IBA
01/2023 - 02/2007
5Messenger RNA (mRNA)IBA
08/2021 - 01/2009
5Transcription Factors (Transcription Factor)IBA
11/2010 - 06/2005
4bosutinibIBA
10/2023 - 01/2013
4Imatinib Mesylate (Gleevec)FDA Link
05/2013 - 04/2006
3InterferonsIBA
03/2024 - 01/2019
3Histones (Histone)IBA
03/2012 - 04/2002
3EphB6 ReceptorIBA
01/2012 - 07/2009
2Janus KinasesIBA
02/2024 - 06/2015
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2023 - 07/2022
2imetelstatIBA
01/2023 - 07/2022
2Thrombopoietin ReceptorsIBA
11/2021 - 01/2016
2AnticoagulantsIBA
10/2021 - 02/2020
2Interferon-alpha (Interferon Alfa)IBA
09/2021 - 01/2019
2Lipocalin-2IBA
08/2021 - 11/2020
2Heparin (Liquaemin)FDA LinkGeneric
01/2021 - 06/2003
2Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2021 - 02/2020
2Creatine Kinase (Creatine Phosphokinase)IBA
01/2020 - 01/2020
2EnzymesIBA
11/2019 - 01/2019
2Lysine (L-Lysine)FDA Link
01/2019 - 11/2010
2ChromatinIBA
01/2018 - 11/2010
2bcr-abl Fusion ProteinsIBA
05/2017 - 11/2003
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
05/2017 - 01/2007
2Rituximab (Mabthera)FDA Link
12/2011 - 04/2010
2DNA (Deoxyribonucleic Acid)IBA
04/2010 - 02/2007
2CCAAT-Enhancer-Binding Protein-alphaIBA
02/2009 - 06/2005
2Immunoglobulins (Immunoglobulin)IBA
02/2007 - 06/2003
1CalciumIBA
03/2024
1Thrombopoietin (c-mpl Ligand)IBA
03/2024
1ErythropoietinFDA Link
03/2024
1Interferon alpha-2 (Roferon-A)FDA Link
03/2024
1Zinc Finger Protein GLI1IBA
12/2023
1Janus Kinase 1IBA
12/2023
1Tryptases (Tryptase)IBA
01/2023
1Antimalarials (Antimalarial Agents)IBA
12/2022
1navtemadlin; 2- ((3R,5R,6S)- 5- (3- chlorophenyl)- 6- (4- chlorophenyl)- 1- ((S)- 1- (isopropylsulfonyl)- 3- methylbutan- 2- yl)- 3- methyl- 2- oxopiperidin- 3- yl)acetic acidIBA
11/2022
1Macrophage Migration-Inhibitory FactorsIBA
11/2022
1AntipruriticsIBA
10/2022
1Nonsense Codon (Nonsense Mutation)IBA
03/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022
1Mutant Proteins (Protein, Mutant)IBA
01/2022
1anagrelide (Agrylin)FDA LinkGeneric
09/2021
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
08/2021
1Uric Acid (Urate)IBA
08/2021
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
06/2021

Therapy/Procedure

31Therapeutics
03/2024 - 02/2002
8Drug Therapy (Chemotherapy)
04/2022 - 03/2002
5Stem Cell Transplantation
12/2023 - 09/2012
1Hematopoietic Stem Cell Mobilization
01/2023
1Precision Medicine
11/2022
1Indwelling Catheters (Indwelling Catheter)
06/2021