Marina Y Konopleva Selected Research

eIF-2 Kinase (eIF 2 Kinase)

9/2015

PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.

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Marina Y Konopleva Research Topics

Disease

41	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2024 - 04/2010
14	Neoplasms (Cancer) 01/2024 - 09/2015
6	Leukemia 01/2023 - 09/2015
5	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 04/2024 - 06/2012
3	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 03/2017
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2019 - 12/2014
2	Cytopenia 01/2022 - 01/2021
2	Thrombocytopenia (Thrombopenia) 01/2021 - 01/2021
2	Philadelphia Chromosome 01/2020 - 12/2016
2	Residual Neoplasm 12/2016 - 12/2014
1	Turcot syndrome 03/2024
1	Cytokine Release Syndrome 01/2024
1	Protein Deficiency 01/2023
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2023
1	Disease Progression 12/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Infections 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 12/2021
1	Bites and Stings (Sting) 01/2021
1	Neutropenia 01/2021
1	Primary Myelofibrosis (Myelosclerosis) 01/2021
1	Anemia 01/2021
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2020
1	Squamous Cell Carcinoma of Head and Neck 03/2017
1	Ataxia Telangiectasia (Louis Bar Syndrome) 09/2015
1	Hypoxia (Hypoxemia) 02/2011

Drug/Important Bio-Agent (IBA)

24	venetoclaxIBA 04/2024 - 02/2017
9	Decitabine FDA Link 04/2024 - 01/2021
7	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2023 - 04/2010
6	Azacitidine (5 Azacytidine)FDA Link 12/2023 - 12/2017
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2011
3	RG7388IBA 01/2023 - 05/2020
2	MethyltransferasesIBA 01/2023 - 01/2023
2	Lysine (L-Lysine)FDA Link 01/2023 - 12/2018
2	Cladribine FDA LinkGeneric 01/2023 - 11/2022
2	Immune Checkpoint InhibitorsIBA 01/2022 - 10/2021
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 03/2017
2	Histones (Histone)IBA 12/2019 - 10/2019
2	Histone Deacetylase InhibitorsIBA 12/2017 - 06/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2017 - 12/2016
2	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 06/2012 - 04/2010
1	AntigensIBA 01/2024
1	CytokinesIBA 01/2024
1	cobimetinibIBA 01/2024
1	tagraxofuspIBA 12/2023
1	Interleukin-3 (Interleukin 3)IBA 12/2023
1	Diphtheria ToxinIBA 12/2023
1	Interleukin-3 Receptors (Interleukin 3 Receptor)IBA 12/2023
1	Programmed Cell Death 1 ReceptorIBA 01/2023
1	NivolumabIBA 01/2023
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2023
1	DNA (Deoxyribonucleic Acid)IBA 01/2023
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	fms-Like Tyrosine Kinase 3IBA 01/2022
1	B-Cell Activating FactorIBA 12/2021
1	avelumabIBA 10/2021
1	Janus Kinase InhibitorsIBA 01/2021
1	AzolesIBA 01/2021
1	LCL161IBA 01/2021
1	Hemoglobins (Hemoglobin)IBA 01/2021
1	CR 6IBA 01/2020
1	bcr-abl Fusion ProteinsIBA 01/2020
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 12/2019
1	AMP-Activated Protein KinasesIBA 12/2019
1	ChromatinIBA 12/2019
1	Protein Kinases (Protein Kinase)IBA 12/2019
1	Glucose (Dextrose)FDA LinkGeneric 12/2019
1	Adenosine Monophosphate (AMP)IBA 12/2019
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 10/2019
1	SB939 compoundIBA 12/2017
1	Cisplatin (Platino)FDA LinkGeneric 03/2017
1	Lactic Acid (Lactate)FDA LinkGeneric 03/2017
1	Carboplatin (JM8)FDA LinkGeneric 03/2017
1	PlatinumIBA 03/2017
1	Cytochrome P-450 CYP3AIBA 02/2017
1	Antifungal AgentsIBA 02/2017
1	Cytochrome P-450 CYP3A InhibitorsIBA 02/2017
1	posaconazole FDA Link 02/2017
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2016
1	Vincristine (Oncovin)FDA LinkGeneric 12/2016
1	Dasatinib (BMS 354825)FDA Link 12/2016
1	ponatinibIBA 12/2016
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2016
1	InterferonsIBA 09/2015
1	eIF-2 Kinase (eIF 2 Kinase)IBA 09/2015
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 09/2015
1	Double-Stranded RNA (RNA, Double Stranded)IBA 09/2015
1	MK 2206IBA 04/2014
1	Vorinostat FDA Link 06/2012
1	Chemokine ReceptorsIBA 02/2011
1	Sorafenib (BAY 43-9006)FDA Link 04/2010

Therapy/Procedure

20	Therapeutics 03/2024 - 04/2010
12	Drug Therapy (Chemotherapy) 01/2024 - 03/2017
1	Drug Tapering 01/2022
1	Cell Transplantation 01/2022
1	Induction Chemotherapy 01/2022
1	Radiotherapy 01/2020