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Yoshihiro Komada Selected Research

Pulmonary Hypertension

4/2020A non-selective endothelin receptor antagonist bosentan modulates kinetics of bone marrow-derived cells in ameliorating pulmonary hypertension in mice.
1/2015Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats.
7/2008Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats.
10/2007A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.

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Yoshihiro Komada Research Topics

Disease

18Neoplasms (Cancer)
12/2021 - 04/2004
9Neuroblastoma
01/2018 - 07/2003
7Leukemia
12/2020 - 04/2004
7Infections
02/2013 - 04/2003
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2019 - 04/2004
4Hypoxia (Hypoxemia)
04/2020 - 06/2014
4Pulmonary Hypertension
04/2020 - 10/2007
4Graft vs Host Disease (Graft-Versus-Host Disease)
07/2013 - 07/2005
2Carcinogenesis
01/2018 - 08/2005
2Ewing Sarcoma (Sarcoma, Ewing)
01/2017 - 02/2005
2Atypical Hemolytic Uremic Syndrome
04/2016 - 11/2014
2Right Ventricular Hypertrophy
03/2015 - 10/2007
2Vascular Diseases (Vascular Disease)
03/2015 - 10/2007
2Thrombotic Thrombocytopenic Purpura
07/2013 - 02/2013
2Wiskott-Aldrich Syndrome
07/2013 - 02/2013
2Pathologic Constriction (Stenosis)
06/2009 - 01/2005
2Inflammation (Inflammations)
06/2009 - 01/2005
2Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
06/2009 - 01/2005
2Aneurysm (Aneurysms)
06/2009 - 01/2005
2Measles
10/2006 - 04/2003
2Atrioventricular Block
07/2006 - 04/2005
2Carcinoma (Carcinomatosis)
05/2005 - 11/2004
1Death (Near-Death Experience)
12/2021
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2020
1Cytopenia
11/2018
1Autoimmune Diseases (Autoimmune Disease)
11/2018
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
11/2018
1Hemolytic Anemia
11/2018
1Osteosarcoma (Osteogenic Sarcoma)
01/2017
1Gastroenteritis
04/2016
1Pharyngitis (Sore Throat)
04/2016
1Lymphoma (Lymphomas)
01/2016
1Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2016
1Invasive Candidiasis
06/2015
1Aspergillosis
06/2015
1Invasive Fungal Infections
06/2015

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
12/2020 - 07/2003
4DNA (Deoxyribonucleic Acid)IBA
06/2014 - 06/2005
4Biomarkers (Surrogate Marker)IBA
01/2013 - 07/2005
4CytokinesIBA
04/2012 - 04/2003
3Interleukin-6 (Interleukin 6)IBA
04/2020 - 01/2005
3Interleukin-10 (Interleukin 10)IBA
01/2013 - 04/2003
3Messenger RNA (mRNA)IBA
09/2012 - 07/2008
3Interleukin-4 (Interleukin 4)IBA
04/2012 - 04/2003
3EnzymesIBA
01/2012 - 11/2004
3Caspase 8 (Caspase-8)IBA
11/2009 - 07/2003
2Endothelin Receptor AntagonistsIBA
04/2020 - 03/2015
2Rituximab (Mabthera)FDA Link
11/2018 - 07/2013
2SteroidsIBA
11/2018 - 02/2013
2(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
01/2018 - 01/2018
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
03/2015 - 01/2015
2Semaxinib (SU5416)IBA
03/2015 - 01/2015
2MK 2206IBA
01/2015 - 01/2015
2Caspase 3 (Caspase-3)IBA
09/2013 - 07/2003
2Indicators and Reagents (Reagents)IBA
01/2013 - 07/2005
2CaspasesIBA
07/2010 - 08/2007
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2008 - 04/2003
2LigandsIBA
10/2008 - 12/2003
2VaccinesIBA
10/2006 - 04/2003
2Interleukin-12 (IL 12)IBA
02/2006 - 04/2003
2Cytidine DeaminaseIBA
05/2005 - 11/2004
2Cytarabine (Cytosar-U)FDA LinkGeneric
05/2005 - 11/2004
2Deoxycytidine KinaseIBA
05/2005 - 11/2004
2DeoxycytidineIBA
05/2005 - 11/2004
1IntegrinsIBA
12/2020
1Cadherins (E-Cadherin)IBA
12/2020
1SodiumIBA
04/2020
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
04/2020
1Endothelin Receptors (Endothelin Receptor)IBA
04/2020
1SaltsIBA
04/2020
1enhanced green fluorescent proteinIBA
04/2020
1Bosentan (Tracleer)FDA Link
04/2020
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
04/2020
1Antiviral Agents (Antivirals)IBA
01/2020
1MicroRNAs (MicroRNA)IBA
08/2019
1Immunosuppressive Agents (Immunosuppressants)IBA
11/2018
1TOR Serine-Threonine KinasesIBA
01/2018
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018
1Mechanistic Target of Rapamycin Complex 1IBA
01/2018
1pirarubicinIBA
04/2017
1AnthracyclinesIBA
04/2017
1Daunorubicin (Cerubidine)FDA LinkGeneric
04/2017
1Complement C3 (C3 Complement)IBA
04/2016
1NucleotidesIBA
04/2016
1eculizumabFDA Link
04/2016
1Complement Inactivating AgentsIBA
04/2016
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2016
1Caspofungin (Cancidas)FDA Link
06/2015
1macitentanIBA
03/2015

Therapy/Procedure

10Therapeutics
01/2020 - 04/2004
8Drug Therapy (Chemotherapy)
01/2018 - 04/2004
5Hematopoietic Stem Cell Transplantation
07/2013 - 07/2005
2Radiotherapy
01/2017 - 09/2007
2Stem Cell Transplantation
12/2008 - 06/2005
2Photochemotherapy (Photodynamic Therapy)
09/2007 - 02/2005
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
06/2002 - 04/2002
1Terminal Care (Care, Terminal)
12/2021
1Palliative Care (Palliative Therapy)
12/2021
1Combination Drug Therapy (Combination Chemotherapy)
01/2017
1Renal Dialysis (Hemodialysis)
04/2016