Jae-Young Koh Selected Research

Amyloid (Amyloid Fibrils)

1/2019	Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system.
1/2019	Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation.
1/2017	Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
3/2014	Tissue plasminogen activator arrests Alzheimer's disease pathogenesis.
12/2010	Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain.
8/2007	Upregulation of tPA/plasminogen proteolytic system in the periphery of amyloid deposits in the Tg2576 mouse model of Alzheimer's disease.

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Jae-Young Koh Research Topics

Disease

21	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 09/2003
14	Brain Injuries (Brain Injury) 03/2020 - 11/2003
7	Seizures (Absence Seizure) 04/2019 - 08/2003
7	Ischemia 08/2016 - 05/2004
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2019 - 12/2005
5	Brain Ischemia (Cerebral Ischemia) 11/2022 - 10/2004
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 05/2004
5	Wounds and Injuries (Trauma) 01/2020 - 08/2009
5	Ischemic Stroke 09/2015 - 10/2004
5	Amyloid Plaque 03/2014 - 05/2002
4	Stroke (Strokes) 01/2020 - 05/2009
4	Epilepsy (Aura) 01/2020 - 08/2009
4	Neoplasms (Cancer) 11/2016 - 07/2008
4	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 12/2010 - 03/2004
3	Diabetic Retinopathy (Retinopathy, Diabetic) 10/2020 - 12/2007
3	Parkinson Disease (Parkinson's Disease) 12/2019 - 08/2009
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2017 - 01/2014
3	Autistic Disorder (Autism) 01/2016 - 09/2014
3	Necrosis 09/2015 - 10/2003
3	Breast Neoplasms (Breast Cancer) 01/2015 - 12/2010
3	Infarction (Infarctions) 05/2009 - 10/2004
2	Glioma (Gliomas) 01/2022 - 01/2020
2	Neuroblastoma 01/2022 - 12/2015
2	Multiple Sclerosis 05/2020 - 10/2016
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 05/2020 - 10/2016
2	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2020 - 11/2013
2	Hypoxia (Hypoxemia) 01/2020 - 05/2003
2	Retinoblastoma (Glioblastoma, Retinal) 11/2016 - 07/2008
2	Megalencephaly 01/2016 - 09/2014
2	Nervous System Diseases (Neurological Disorders) 09/2015 - 11/2011
2	Hyperglycemia 09/2014 - 12/2007
2	Cerebral Hemorrhage 12/2013 - 10/2004
1	Brain Diseases (Brain Disorder) 11/2022
1	Frontotemporal Dementia (Semantic Dementia) 01/2022
1	Brain Infarction 01/2019
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019
1	Retinal Detachment (Retinal Detachments) 01/2018
1	Body Weight (Weight, Body) 11/2016
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 12/2015

Drug/Important Bio-Agent (IBA)

39	ZincIBA 11/2022 - 05/2002
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2003
6	Amyloid (Amyloid Fibrils)IBA 01/2019 - 08/2007
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2020 - 12/2005
5	zinc-binding protein (zinc binding protein)IBA 05/2020 - 05/2002
5	Amyloid beta-PeptidesIBA 01/2020 - 02/2004
4	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 12/2007
4	Pyruvic Acid (Pyruvate)IBA 12/2015 - 05/2004
4	Tissue Plasminogen Activator (Alteplase)FDA Link 03/2014 - 10/2004
4	Neuroprotective AgentsIBA 11/2013 - 10/2004
4	Kainic Acid (Kainate)IBA 04/2012 - 08/2003
3	Biomarkers (Surrogate Marker)IBA 03/2020 - 05/2009
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 11/2007
3	Riluzole FDA LinkGeneric 01/2017 - 12/2005
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2016 - 10/2003
2	Chelating AgentsIBA 11/2022 - 05/2020
2	Protein AggregatesIBA 01/2022 - 12/2019
2	Phosphodiesterase 3 InhibitorsIBA 01/2020 - 12/2015
2	Cilostazol (Pletal)FDA LinkGeneric 01/2020 - 12/2015
2	Small Interfering RNA (siRNA)IBA 01/2020 - 01/2019
2	MetallothioneinIBA 01/2020 - 10/2011
2	Oxygen (Dioxygen)IBA 01/2020 - 12/2007
2	Beclin-1IBA 01/2019 - 06/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 05/2004
2	AMP-Activated Protein KinasesIBA 01/2019 - 01/2015
2	Protein Kinase CIBA 01/2017 - 12/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2017 - 09/2014
2	Estrogen ReceptorsIBA 01/2015 - 12/2013
2	Retinaldehyde (Retinal)IBA 06/2012 - 05/2004
2	PlasminogenIBA 04/2012 - 08/2007
2	IronIBA 11/2004 - 10/2003
1	tau Proteins (tau Protein)IBA 01/2022
1	Proton Pumps (Proton Pump)IBA 01/2021
1	Adenosine Triphosphatases (ATPase)IBA 01/2021
1	InterleukinsIBA 03/2020
1	lipoxin A4IBA 03/2020
1	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 01/2020
1	CalciumIBA 01/2020
1	InflammasomesIBA 01/2020
1	4- cyclohexylmethoxy- 5- nitrosopyrimidine- 2,6- diamineIBA 04/2019
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2019
1	Green Fluorescent ProteinsIBA 01/2019
1	Phenobarbital (Luminal)FDA Link 01/2019
1	LuciferasesIBA 01/2019
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2018
1	afliberceptIBA 11/2016
1	Myelin-Oligodendrocyte GlycoproteinIBA 10/2016
1	florbetapirIBA 01/2016
1	Matrix Metalloproteinase InhibitorsIBA 01/2016
1	Minocycline (Cyclops)FDA LinkGeneric 01/2016
1	Heterogeneous Nuclear Ribonucleoprotein A1IBA 12/2015
1	IonsIBA 09/2015
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 09/2015
1	Carisoprodol (Soma)FDA LinkGeneric 09/2015
1	Indomethacin (Indometacin)FDA LinkGeneric 09/2015
1	Cyclooxygenase InhibitorsIBA 09/2015
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2015

Therapy/Procedure

4	Therapeutics 01/2021 - 12/2007
1	Injections 01/2019
1	Heterologous Transplantation (Xenotransplantation) 11/2016
1	Drug Therapy (Chemotherapy) 11/2016