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Josephine Mun Yee Ko Selected Research

Esophageal Squamous Cell Carcinoma

11/2023Circulating Tumor DNA Dynamics as Prognostic Markers in Locally Advanced and Metastatic Esophageal Squamous Cell Carcinoma.
9/2021RAD50 Loss of Function Variants in the Zinc Hook Domain Associated with Higher Risk of Familial Esophageal Squamous Cell Carcinoma.
10/2019Endoplasmic reticulum-localized ECM1b suppresses tumor growth and regulates MYC and MTORC1 through modulating MTORC2 activation in esophageal squamous cell carcinoma.
12/2018Chemotherapeutic Treatments Increase PD-L1 Expression in Esophageal Squamous Cell Carcinoma through EGFR/ERK Activation.
3/2012The LIM domain protein, CRIP2, promotes apoptosis in esophageal squamous cell carcinoma.

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Josephine Mun Yee Ko Research Topics

Disease

9Neoplasms (Cancer)
09/2020 - 08/2009
5Esophageal Squamous Cell Carcinoma
11/2023 - 03/2012
4Nasopharyngeal Carcinoma
05/2015 - 07/2010
3Neoplasm Metastasis (Metastasis)
09/2020 - 11/2016
2Carcinogenesis
10/2016 - 03/2012
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2015 - 07/2010
1Disease Progression
11/2023
1Residual Neoplasm
11/2023
1Circulating Neoplastic Cells
05/2020
1Ovarian Neoplasms (Ovarian Cancer)
02/2018
1Hepatocellular Carcinoma (Hepatoma)
02/2018
1Pathologic Constriction (Stenosis)
01/2015
1Epstein-Barr Virus Infections
11/2014
1Carcinoma (Carcinomatosis)
09/2013
1Esophageal Neoplasms (Esophageal Cancer)
07/2010

Drug/Important Bio-Agent (IBA)

4Biomarkers (Surrogate Marker)IBA
11/2023 - 02/2018
4Proteins (Proteins, Gene)FDA Link
02/2018 - 03/2012
2matrigelIBA
01/2012 - 07/2010
1Circulating Tumor DNAIBA
11/2023
1ZincIBA
09/2021
1CyclinsIBA
09/2020
1Fanconi Anemia Complementation Group D2 ProteinIBA
09/2020
1Cell-Free Nucleic AcidsIBA
05/2020
1DNA (Deoxyribonucleic Acid)IBA
05/2020
1Mechanistic Target of Rapamycin Complex 2IBA
10/2019
1Mechanistic Target of Rapamycin Complex 1IBA
10/2019
1Nucleosomes (Nucleosome)IBA
01/2017
1Histones (Histone)IBA
01/2017
1IntegrinsIBA
11/2016
1Interleukin-6 (Interleukin 6)IBA
05/2015
1Interleukin-8 (Interleukin 8)IBA
05/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2015
1Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA
05/2015
1Phenobarbital (Luminal)FDA Link
01/2015
1Small Interfering RNA (siRNA)IBA
01/2015
1HLA Antigens (Human Leukocyte Antigens)IBA
11/2014
1CateninsIBA
09/2013
1Cadherins (E-Cadherin)IBA
09/2013
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2012
1Cysteine (L-Cysteine)FDA Link
03/2012
1Dual Specificity Phosphatase 6IBA
01/2012
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2012
1Dual-Specificity PhosphatasesIBA
01/2012
1Phosphotransferases (Kinase)IBA
01/2012
1Metalloproteases (Metalloproteinases)IBA
07/2010
1Peptide Hydrolases (Proteases)FDA Link
07/2010
1Cyclin-Dependent Kinase Inhibitor p27IBA
08/2009

Therapy/Procedure

2Drug Therapy (Chemotherapy)
05/2020 - 12/2018