Georgeanna Klingensmith Selected Research

Autoantibodies

9/2022	ZnT8 autoantibody prevalence is low in youth with type 2 diabetes and associated with higher insulin sensitivity, lower insulin secretion, and lower disposition index.
1/2018	Can Biomarkers Help Target Maturity-Onset Diabetes of the Young Genetic Testing in Antibody-Negative Diabetes?
9/2015	Comparison of Metabolic Outcomes in Children Diagnosed with Type 1 Diabetes Through Research Screening (Diabetes Autoimmunity Study in the Young [DAISY]) Versus in the Community.
4/2015	Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.
6/2011	Analysis of pathogenesis of juvenile new-onset diabetes.
12/2010	Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY).
2/2009	Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes.
1/2007	Prevalence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity.
10/2006	Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY).

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Georgeanna Klingensmith Research Topics

Disease

23	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2022 - 05/2002
10	Type 2 Diabetes Mellitus (MODY) 09/2022 - 07/2005
5	Insulinoma 04/2015 - 10/2006
3	Insulin Resistance 09/2022 - 03/2009
3	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2016 - 05/2002
2	Ketosis 01/2019 - 05/2002
2	Mason-Type Diabetes 01/2018 - 01/2016
2	Dyslipidemias (Dyslipidemia) 01/2017 - 03/2009
2	Non-alcoholic Fatty Liver Disease 01/2017 - 07/2005
2	Diabetes Mellitus 05/2015 - 11/2011
2	Hypoglycemia (Reactive Hypoglycemia) 04/2015 - 05/2002
2	Obesity 03/2009 - 01/2007
2	Body Weight (Weight, Body) 03/2004 - 12/2003
1	Diabetes Complications 09/2022
1	Hyperglycemia 01/2019
1	Hypertension (High Blood Pressure) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2015
1	Deafness (Deaf Mutism) 11/2011
1	Diabetes Insipidus 11/2011
1	Macular Degeneration (Age-Related Maculopathy) 11/2011
1	Optic Atrophy 11/2011
1	Enterovirus Infections 12/2010
1	Genetic Predisposition to Disease (Genetic Predisposition) 02/2009
1	Mental Disorders (Mental Disorder) 05/2002

Drug/Important Bio-Agent (IBA)

13	Insulin (Novolin)FDA Link 01/2016 - 05/2002
9	AutoantibodiesIBA 09/2022 - 10/2006
4	Hemoglobins (Hemoglobin)IBA 01/2016 - 12/2003
4	AntigensIBA 04/2015 - 12/2010
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2003
3	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 04/2015 - 10/2006
2	insulin degludecIBA 01/2019 - 05/2015
2	Insulin Aspart (NovoLog)FDA Link 01/2019 - 05/2015
2	Insulin Detemir (Levemir)FDA Link 01/2019 - 05/2015
2	Metformin (Glucophage)FDA LinkGeneric 05/2015 - 06/2006
2	HLA Antigens (Human Leukocyte Antigens)IBA 04/2015 - 10/2006
2	Insulin Glargine (Lantus)FDA Link 09/2005 - 12/2003
1	Liraglutide FDA Link 01/2020
1	KetonesIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	C-PeptideIBA 01/2018
1	C-Reactive ProteinIBA 01/2018
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2017
1	Vitamin D FDA LinkGeneric 12/2016
1	Immunoglobulin E (IgE)IBA 04/2015
1	HLA-DR Antigens (HLA-DR)IBA 12/2012
1	wolframin proteinIBA 11/2011
1	ZincIBA 06/2011
1	AntibodiesIBA 06/2011
1	RNA (Ribonucleic Acid)IBA 12/2010
1	Viral RNAIBA 12/2010
1	AlbuminsIBA 03/2009
1	CreatinineIBA 03/2009
1	Transcription Factors (Transcription Factor)IBA 02/2009
1	Bicarbonates (Hydrogen Carbonate)IBA 05/2008
1	Glutamic Acid (Glutamate)FDA Link 01/2007
1	Rosiglitazone (Avandia)FDA Link 06/2006
1	LipidsIBA 07/2005
1	Transaminases (Aminotransferases)IBA 07/2005
1	Alanine Transaminase (SGPT)IBA 07/2005
1	Hypoglycemic Agents (Hypoglycemics)IBA 12/2003
1	Isophane Insulin (NPH Insulin)FDA Link 12/2003
1	Hemoglobin AIBA 05/2002

Therapy/Procedure

8	Glycemic Control 09/2022 - 12/2003
4	Therapeutics 05/2015 - 07/2005
2	Ambulatory Care (Outpatient Care) 10/2006 - 12/2003
1	Oral Administration 04/2015