Alexei F Kisselev Selected Research

Chymotrypsin

5/2011	Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib.
3/2006	Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate.

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Alexei F Kisselev Research Topics

Disease

11	Multiple Myeloma 01/2022 - 05/2011
11	Neoplasms (Cancer) 01/2021 - 03/2006
3	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2021 - 01/2012
2	Cockayne Syndrome (Syndrome, Cockayne) 06/2006 - 05/2003
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021
1	Genetic Translocation (Chromosomal Translocation) 01/2021
1	Triple Negative Breast Neoplasms 02/2017
1	Hematologic Neoplasms (Hematological Malignancy) 03/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 08/2015
1	Autoimmune Diseases (Autoimmune Disease) 12/2014
1	Lung Neoplasms (Lung Cancer) 04/2014
1	Human Influenza (Influenza) 08/2012
1	Reperfusion Injury 01/2012
1	Leukemia 07/2011
1	Inborn Genetic Diseases (Disease, Hereditary) 05/2003
1	Xeroderma Pigmentosum (Kaposi's Disease) 05/2003

Drug/Important Bio-Agent (IBA)

11	Proteasome InhibitorsIBA 01/2022 - 03/2006
10	Bortezomib (Velcade)FDA Link 01/2022 - 05/2011
7	carfilzomibIBA 01/2022 - 05/2011
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2003
5	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2017 - 06/2006
2	ixazomibIBA 12/2021 - 10/2018
2	TrypsinIBA 04/2014 - 02/2013
2	UbiquitinIBA 12/2013 - 06/2006
2	Chymotrypsin FDA Link 05/2011 - 03/2006
1	marizomibIBA 12/2021
1	azido- Phe- Leu- Leu- 4- aminomethyl- Phe- methyl vinyl sulfoneIBA 08/2015
1	ibrutinibIBA 08/2015
1	Agammaglobulinaemia Tyrosine KinaseIBA 08/2015
1	I-kappa B Proteins (I kappa B)IBA 08/2015
1	Peptide Hydrolases (Proteases)FDA Link 04/2014
1	ATP dependent 26S protease (26S proteasome)IBA 12/2013
1	EpitopesIBA 08/2012
1	Peptides (Polypeptides)IBA 06/2007
1	DDBIBA 05/2003

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2020
1	Radiotherapy 01/2020
1	Therapeutics 03/2006