Michael D Keller Selected Research

Infections

4/2024	Third-party virus specific T cells for the treatment of double stranded DNA viral reactivation and PTLD after solid organ transplant.
1/2023	Third-Party and Patient-Specific Donor-Derived Virus-Specific T Cells Demonstrate Similar Efficacy and Safety for Management of Viral Infections after Hematopoietic Stem Cell Transplantation in Children and Young Adults.
12/2022	Natural history of infants with non-SCID T cell lymphopenia identified on newborn screen.
10/2022	Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant.
9/2022	Robust immune responses to SARS-CoV-2 in a pediatric patient with B-Cell ALL receiving tisagenlecleucel.
1/2021	Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted.
1/2021	Case Report: Unmanipulated Matched Sibling Donor Hematopoietic Cell Transplantation In TBX1 Congenital Athymia: A Lifesaving Therapeutic Approach When Facing a Systemic Viral Infection.
1/2020	T-Cell Therapeutics Targeting Human Parainfluenza Virus 3 Are Broadly Epitope Specific and Are Cross Reactive With Human Parainfluenza Virus 1.
1/2020	EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects.
1/2019	Case Report: Ocular toxoplasmosis in a WHIM syndrome immunodeficiency patient.

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Michael D Keller Research Topics

Disease

16	Virus Diseases (Viral Diseases) 04/2024 - 01/2014
14	Infections 04/2024 - 12/2016
10	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 03/2024 - 04/2007
8	Primary Immunodeficiency Diseases 01/2023 - 01/2018
7	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2024 - 01/2016
6	COVID-19 11/2023 - 12/2020
4	Hematologic Neoplasms (Hematological Malignancy) 01/2023 - 01/2020
4	Neoplasms (Cancer) 01/2021 - 04/2004
2	Thrombotic Microangiopathies 04/2024 - 01/2023
2	Wiskott-Aldrich Syndrome 08/2023 - 01/2020
2	Lymphopenia (Lymphocytopenia) 12/2022 - 01/2021
2	Inflammation (Inflammations) 12/2020 - 01/2019
2	Paramyxoviridae Infections (Parainfluenza) 01/2020 - 12/2016
2	Chronic Granulomatous Disease 10/2018 - 05/2018
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2004 - 04/2004
1	Viremia 03/2024
1	Pneumonia (Pneumonitis) 11/2023
1	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 11/2023
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2023
1	Cytopenia 01/2023
1	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2023
1	Opportunistic Infections (Opportunistic Infection) 12/2022
1	Mycoses (Diseases, Fungus) 12/2022
1	Common Variable Immunodeficiency 11/2022
1	Cytokine Release Syndrome 09/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Febrile Ulceronecrotic Mucha-Habermann disease 11/2021
1	Thymoma (Thymic Carcinoma) 11/2021
1	Testicular Neoplasms (Testicular Cancer) 01/2021
1	Adenoviridae Infections (Adenovirus Infections) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2021
1	Disease Progression 01/2021
1	Lymphoma (Lymphomas) 01/2020
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2020
1	Protozoan Infections 01/2019
1	Tuberculosis (Tuberculoses) 01/2019
1	Retinitis 01/2019
1	Blindness (Hysterical Blindness) 01/2019
1	WHIM syndrome 01/2019
1	Toxoplasmosis 01/2019
1	Ectodermal Dysplasia (Aplasia Cutis Congenita) 10/2018
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 10/2018
1	Autosomal Recessive 3 Severe Congenital Neutropenia 10/2018
1	Atypical Hemolytic Uremic Syndrome 02/2013

Drug/Important Bio-Agent (IBA)

6	Antiviral Agents (Antivirals)IBA 01/2023 - 01/2016
4	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 01/2020
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2012
3	Transcription Factors (Transcription Factor)IBA 12/2022 - 04/2004
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2022 - 04/2007
3	VaccinesIBA 12/2022 - 11/2021
3	AntigensIBA 01/2021 - 12/2016
3	Peptides (Polypeptides)IBA 01/2021 - 01/2020
2	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2024 - 10/2022
2	AutoantibodiesIBA 11/2023 - 01/2019
2	CytokinesIBA 11/2021 - 01/2021
2	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2004 - 04/2004
2	NF-kappa B (NF-kB)IBA 10/2004 - 04/2004
1	eculizumab FDA Link 04/2024
1	Interferon Type IIBA 11/2023
1	Myelin-Oligodendrocyte GlycoproteinIBA 08/2023
1	Adenosine DeaminaseIBA 01/2023
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2023
1	I-kappa B KinaseIBA 01/2023
1	elapegademaseIBA 01/2023
1	Rituximab (Mabthera)FDA Link 11/2022
1	Messenger RNA (mRNA)IBA 11/2022
1	blinatumomabIBA 09/2022
1	Chimeric Antigen ReceptorsIBA 09/2022
1	tisagenlecleucelIBA 09/2022
1	CD40 Ligand (CD40L)IBA 01/2022
1	ruxolitinibIBA 11/2021
1	tocilizumab (atlizumab)FDA Link 11/2021
1	mRNA VaccinesIBA 11/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 12/2020
1	EpitopesIBA 01/2020
1	alpha-beta T-Cell Antigen Receptors (T-Cell Receptor alpha-Chain)IBA 10/2019
1	Pyrimethamine (Daraprim)FDA Link 01/2019
1	Retinaldehyde (Retinal)IBA 01/2019
1	Sulfadiazine (Sulphadiazine)FDA Link 01/2019
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2019
1	SteroidsIBA 01/2019
1	Immunoglobulin M (IgM)IBA 10/2018
1	NF-KappaB Inhibitor alphaIBA 10/2018
1	Interferon Regulatory FactorsIBA 01/2017
1	Folic Acid (Vitamin M)FDA LinkGeneric 02/2013

Therapy/Procedure

19	Therapeutics 04/2024 - 02/2013
11	Hematopoietic Stem Cell Transplantation 01/2023 - 01/2014
7	Transplantation 01/2023 - 01/2016
5	Immunotherapy 01/2021 - 01/2014
4	Drug Therapy (Chemotherapy) 01/2023 - 04/2004
4	Cell Transplantation 01/2023 - 10/2018
3	Stem Cell Transplantation 01/2021 - 01/2019
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 03/2024 - 12/2020
1	Enzyme Replacement Therapy 01/2023
1	Length of Stay 01/2023
1	Homologous Transplantation 10/2022
1	Art Therapy 01/2020
1	Bridge Therapy 01/2018