Keith S Kaye Selected Research

Tazobactam Drug Combination Piperacillin (Zosyn)

4/2023	Clinical Outcomes With Extended Versus Intermittent Infusion of Anti-Pseudomonal Beta-Lactams in Patients With Gram-Negative Bacteremia.
1/2023	Cefepime/Enmetazobactam vs Piperacillin/Tazobactam and Complicated Urinary Tract Infection or Acute Pyelonephritis-Reply.
10/2022	Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis: A Randomized Clinical Trial.
12/2021	A Randomized, Double-blind, Multicenter Trial Comparing Efficacy and Safety of Imipenem/Cilastatin/Relebactam Versus Piperacillin/Tazobactam in Adults With Hospital-acquired or Ventilator-associated Bacterial Pneumonia (RESTORE-IMI 2 Study).
11/2019	Fosfomycin for Injection (ZTI-01) Versus Piperacillin-tazobactam for the Treatment of Complicated Urinary Tract Infection Including Acute Pyelonephritis: ZEUS, A Phase 2/3 Randomized Trial.
1/2018	Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial.
1/2018	Overview of meropenem-vaborbactam and newer antimicrobial agents for the treatment of carbapenem-resistant Enterobacteriaceae.
1/2017	Risk of Acute Kidney Injury in Patients on Concomitant Vancomycin and Piperacillin-Tazobactam Compared to Those on Vancomycin and Cefepime.
1/2016	Epidemiology of Acute Kidney Injury among Patients Receiving Concomitant Vancomycin and Piperacillin-Tazobactam: Opportunities for Antimicrobial Stewardship.
8/2015	Carbapenems Versus Piperacillin-Tazobactam for Bloodstream Infections of Nonurinary Source Caused by Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae.

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Keith S Kaye Research Topics

Disease

113	Infections 05/2024 - 11/2002
28	Sepsis (Septicemia) 01/2024 - 11/2002
25	Bacteremia 01/2024 - 07/2003
21	Urinary Tract Infections (Urinary Tract Infection) 04/2024 - 07/2007
14	Pneumonia (Pneumonitis) 05/2024 - 11/2002
11	Surgical Wound Infection 01/2016 - 08/2006
10	Critical Illness (Critically Ill) 11/2023 - 04/2015
10	Communicable Diseases (Infectious Diseases) 10/2023 - 02/2004
8	Pyelonephritis 12/2023 - 01/2018
8	Acute Kidney Injury (Acute Renal Failure) 07/2023 - 09/2015
8	Respiratory Sounds (Crackle) 01/2020 - 04/2015
7	Bacterial Pneumonia 03/2024 - 05/2014
6	Ventilator-Associated Pneumonia 12/2023 - 07/2007
6	Cross Infection (Nosocomial Infection) 01/2021 - 09/2007
5	Clostridium Infections 10/2023 - 04/2015
5	Obesity 01/2018 - 09/2007
4	Chronic Kidney Failure (Chronic Renal Failure) 01/2023 - 02/2005
4	Bacteriuria 01/2021 - 04/2015
4	Bacterial Infections (Bacterial Infection) 03/2020 - 03/2005
4	Wounds and Injuries (Trauma) 01/2017 - 09/2013
3	Endocarditis 01/2024 - 10/2016
3	Diabetic Foot 10/2023 - 11/2018
3	Leukocytosis (Pleocytosis) 06/2022 - 11/2019
3	Healthcare-Associated Pneumonia 06/2021 - 01/2015
3	Urinary Incontinence 12/2020 - 04/2011
3	Gram-Negative Bacterial Infections 11/2020 - 01/2018
3	Intraabdominal Infections 01/2020 - 01/2017
2	Hypersensitivity (Allergy) 01/2024 - 01/2023
2	Diarrhea 10/2023 - 10/2017
2	Ulcer 10/2023 - 11/2018
2	Respiratory Tract Infections (Respiratory Tract Infection) 12/2022 - 06/2021
2	Cough 12/2022 - 01/2018
2	Osteomyelitis 07/2021 - 03/2019
2	COVID-19 01/2021 - 10/2020
2	Dementia (Dementias) 12/2020 - 11/2019
2	Renal Insufficiency (Renal Failure) 03/2020 - 01/2019
2	Confusion (Bewilderment) 01/2019 - 02/2015
2	Coinfection 01/2019 - 12/2018
2	Human Influenza (Influenza) 01/2018 - 06/2014
2	Peripheral Vascular Diseases (Peripheral Vascular Disease) 06/2015 - 01/2013
2	Staphylococcal Infections 01/2015 - 07/2010
2	Weight Loss (Weight Reduction) 06/2010 - 09/2007

Drug/Important Bio-Agent (IBA)

44	Anti-Bacterial Agents (Antibiotics)IBA 04/2024 - 02/2005
26	Carbapenems (Carbapenem Antibiotics)IBA 03/2023 - 01/2011
21	Colistin (Coly-Mycin)FDA Link 01/2024 - 02/2011
18	Vancomycin FDA LinkGeneric 10/2023 - 03/2012
11	Polymyxins (Polymyxin)IBA 01/2024 - 02/2013
11	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 04/2023 - 08/2007
8	meropenem and vaborbactamIBA 03/2023 - 01/2018
8	carbapenemaseIBA 01/2023 - 01/2016
8	Daptomycin FDA Link 03/2022 - 12/2012
7	Imipenem FDA Link 03/2023 - 08/2007
7	Ceftaroline FDA Link 03/2022 - 05/2014
6	Meropenem (Merrem)FDA LinkGeneric 07/2023 - 04/2012
6	Cefepime (Maxipime)FDA LinkGeneric 04/2023 - 07/2012
6	ceftazidime drug combination avibactamIBA 03/2023 - 01/2018
6	relebactamIBA 03/2023 - 01/2018
6	Cephalosporins (Cephalosporin Antibiotics)IBA 03/2023 - 01/2013
5	Polymyxin B (Aerosporin)FDA LinkGeneric 12/2021 - 02/2015
4	beta-Lactamases (beta-Lactamase)IBA 05/2024 - 04/2006
4	LactamsIBA 03/2024 - 07/2014
4	Imipenem Drug Combination Cilastatin (Primaxin)FDA Link 01/2023 - 01/2020
4	Fosfomycin FDA Link 01/2021 - 02/2013
4	AminoglycosidesIBA 11/2020 - 02/2013
4	Linezolid (Zyvox)FDA Link 07/2014 - 12/2012
3	sulbactam-durlobactamIBA 03/2024 - 01/2023
3	colistinmethanesulfonic acid (colistimethate sodium)FDA LinkGeneric 12/2020 - 11/2020
3	Minocycline (Cyclops)FDA LinkGeneric 06/2017 - 12/2014
3	Tigecycline (Tygacil)FDA Link 04/2015 - 12/2012
2	beta-LactamsIBA 04/2024 - 04/2023
2	FluoroquinolonesIBA 12/2023 - 01/2013
2	plazomicinIBA 03/2023 - 04/2019
2	CefiderocolIBA 03/2023 - 01/2021
2	enmetazobactamIBA 01/2023 - 10/2022
2	CreatinineIBA 01/2023 - 09/2006
2	Drug CombinationsIBA 01/2021 - 01/2020
2	AlbuminsIBA 01/2021 - 11/2016
2	tazobactam drug combination ceftolozaneIBA 11/2020 - 01/2017
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2019 - 12/2012
2	Methicillin (Metin)FDA Link 09/2013 - 02/2005
2	Ciprofloxacin (Cipro)FDA LinkGeneric 03/2009 - 08/2007

Therapy/Procedure

51	Therapeutics 03/2024 - 11/2002
11	Length of Stay 12/2023 - 02/2005
9	Critical Care (Surgical Intensive Care) 10/2023 - 08/2007
7	Catheters 12/2020 - 06/2005
6	Mechanical Ventilators (Ventilator) 03/2024 - 12/2018
3	Home Nursing (Nursing, Home) 01/2023 - 11/2002
3	Duration of Therapy 01/2023 - 12/2005
3	Patient Readmission 11/2019 - 04/2015
3	Long-Term Care 12/2017 - 02/2005
3	Renal Dialysis (Hemodialysis) 06/2005 - 02/2005
2	Tracheostomy 12/2020 - 08/2007
2	Hand Hygiene 11/2019 - 04/2010
2	Antibiotic Prophylaxis 01/2017 - 11/2012
2	Operative Surgical Procedures 01/2016 - 07/2010
2	Urinary Catheters 10/2015 - 08/2013
2	Enteral Nutrition (Feeding, Tube) 10/2015 - 08/2007
2	Bariatric Surgery 11/2012 - 06/2010
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2010 - 07/2003
2	Central Venous Catheters 03/2009 - 12/2005